BREAST CANCER FEMALE

This study is testing a non-surgical treatment for women aged 65 and older with early-stage breast cancer. Instead of surgery, participants receive five precise, high-dose radiation treatments to the tumor. Researchers will track side effects and quality of life to see if this ap…

This study is testing whether taking hormone therapy pills for 3 months before breast cancer surgery helps women aged 65+ with early-stage, hormone-sensitive breast cancer make better decisions about radiation treatment. Participants are randomly assigned to either take the pills…

This study is testing if specific eating patterns can help people during breast cancer chemotherapy. Researchers want to see if eating only during an 8-hour window each day (time-restricted eating), either alone or combined with a Mediterranean-style diet, can reduce treatment si…

This study is testing whether exercise, or exercise combined with diet counseling, can improve heart health and body composition in breast cancer survivors. It will involve 45 women who have completed treatment and are now at risk for metabolic problems. Participants will be rand…

This study is testing a new approach to see if many women with early breast cancer can safely skip radiotherapy after surgery. Researchers will use a special MRI scan and detailed tissue analysis to identify patients with a very low risk of the cancer returning. If successful, th…

This study is testing a specialized radiation machine called GammaPod that delivers a concentrated 'boost' dose to the area where a breast tumor was removed. Researchers want to see if this targeted approach can shorten treatment time by 3-4 sessions while maintaining effectivene…

This study is testing whether high-intensity focused ultrasound (HIFU) can destroy small breast tumors before surgery. It will involve 15 patients with early-stage breast cancer. The goal is to see if this non-invasive technique can effectively remove tumor cells, potentially lea…

This study is testing a new blood test designed to detect breast cancer early. Researchers will enroll 300 women—some with breast cancer and some without—to see if specific markers in the blood can accurately identify the disease. The goal is to develop a simple, non-invasive too…

This study is testing if adding a special type of mammogram that uses contrast dye every two years helps find returning breast cancer more effectively in women with a personal history of the disease. It will involve 1,500 women who get their regular annual mammogram plus this ext…

This study aims to improve breast cancer diagnosis in Nigeria by training local radiologists. Using tablet-based mobile health devices, researchers will teach doctors how to perform ultrasound-guided breast biopsies, a more precise method than current options. The goal is to crea…

This large international study is testing if giving patients a lidocaine (a common numbing medicine) infusion during and for 24 hours after breast cancer surgery can prevent them from developing moderate or severe chronic pain one year later. It will enroll 4,300 women and compar…

This study aims to understand how access to supportive care affects quality of life for women recovering from breast cancer surgery. Researchers will follow 310 women through their treatment journey, comparing those who receive additional supportive care with those who don't. The…

This study is testing two different group exercise programs to see which one better helps breast cancer survivors build muscle mass. The research involves 30 women who have completed breast cancer treatment (except for ongoing hormone therapy). Participants will attend supervised…

This study is testing whether a 12-week program of exercise therapy, with or without cognitive behavioral therapy (CBT), can help reduce fatigue in women who have been treated for breast cancer. The researchers want to see if these programs are practical and acceptable to patient…

This study is testing whether taking a creatine supplement while doing exercise helps breast cancer survivors regain strength, endurance, and muscle mass more quickly after finishing chemotherapy. Researchers will compare 60 breast cancer survivors doing exercise with or without …

This study is testing a thinking-skills training program to help breast cancer survivors who are struggling with memory, focus, and concentration problems after treatment. Researchers will work with 50 participants to see if this training is practical to deliver and if it helps i…

This small pilot study is testing whether a non-invasive brain stimulation technique can reduce nerve pain caused by chemotherapy. Researchers will enroll 19 female breast or gynecologic cancer survivors who developed persistent nerve pain after treatment. Participants will recei…

This study is testing whether daily guided self-hypnosis sessions delivered through a digital app can reduce hot flashes in breast cancer patients taking hormone therapy. Researchers will enroll 76 women experiencing frequent hot flashes to see if this non-drug approach improves …

This study is testing a 12-week exercise program designed to help Black women who have finished their main breast cancer treatment. Researchers want to see if the program is practical and enjoyable for participants, and if it helps improve their outlook and quality of life. The s…

This study aims to understand how exercise might help lower breast cancer risk in women with dense breast tissue. Researchers will compare 46 inactive women who either participate in a 16-week exercise program or wait without exercise. They'll measure changes in blood and breast …

This study aims to learn if a blood test that looks for tiny pieces of tumor DNA can predict how well chemotherapy works for breast cancer patients. It will observe 125 women with stage II or III breast cancer who are receiving chemotherapy before surgery. Researchers will track …

This study aims to understand if the natural bacteria (microbiome) in a person's gut and breast tissue can predict who gets an infection after breast reconstruction surgery. Researchers will compare patients who receive antibiotics after surgery to those who do not, tracking them…

This study aims to grow human breast cancer tumors in mice to create better research models. Researchers will take small pieces of tumor from patients during surgery and implant them into mice. By studying how these tumors grow and change in the mice, scientists hope to learn mor…

This study aims to understand how the temporary lack of oxygen that occurs during breast cancer surgery affects tumor tissue. Researchers will collect small tumor samples from 500 patients at different points during their operation. These samples will be analyzed to see how the t…

This study aims to improve how artificial intelligence (AI) reads mammograms by collecting a large, diverse set of images from 20,000 participants. The goal is to train AI models that work well for all women, reducing false alarms and missed cancers. Participants will also receiv…