BREAST CANCER FEMALE

This early-phase study tested a personalized vaccine made from a patient's own immune cells, designed to target HER2-positive breast cancer. 31 adults with stage II or III breast cancer received the vaccine alongside standard chemotherapy before surgery. The goal was to see if th…

This study tested a treatment called radiofrequency ablation (RFA) for small breast tumors (under 2 cm). RFA uses heat to destroy cancer cells. The study included 30 women with early-stage breast cancer. The main goal was to see if RFA could completely eliminate the tumor, which …

This study tested an AI system called Carebot AI MMG to see if it can read mammograms as accurately as human radiologists. Researchers used 222 past mammograms from four screening centers and compared the AI's findings to those of three experienced breast radiologists. The goal w…

This study tested whether the antioxidant alpha lipoic acid could prevent heart damage caused by the chemotherapy drug doxorubicin in 80 women with breast cancer. Participants received either alpha lipoic acid or a placebo alongside their first round of chemotherapy. The goal was…

This study looked at whether adding nerve mobilization exercises to standard physical therapy can reduce long-term shoulder disability in women after breast cancer surgery. 140 women who had surgery for breast cancer took part. The researchers compared those who received only ear…

This study tested whether a personalized, remote exercise and physical activity coaching program could improve quality of life in women who finished breast cancer treatment. Over 800 women participated, and researchers measured changes in physical and mental well-being after 12 m…

This study tested whether a digital physiotherapy program (TRAK) helps women regain shoulder movement better than standard paper-based home exercises after lymph node removal for breast cancer. Forty women participated in a 4-week home program. Researchers measured shoulder mobil…

This study tested a breast reconstruction method for women who had a mastectomy (breast removal) due to cancer. Instead of placing the implant under the chest muscle, doctors first used fat grafting to prepare the skin and then placed the implant just under the skin. The goal was…

This study tested two simple, drug-free techniques—self-acupressure (pressing specific points on the body) and Zhan Zhuang (a gentle standing meditation)—to help breast cancer survivors manage pain, tiredness, and sleep problems. About 50 women who had finished cancer treatment a…

This study looked at whether adding dexmedetomidine to a standard nerve block (Pecs block) can reduce the need for morphine and improve pain relief after breast cancer surgery. Sixty women aged 18–60 participated. The main goal was to measure total morphine use in the first 48 ho…

This pilot study tested whether a program combining education and group exercise could reduce joint pain caused by aromatase inhibitors (AI) in older breast cancer survivors (aged 60+). Twelve women who were about to start AI medication were randomly assigned to either standard c…

This study tested a new device called the Breast Cancer Locator (BCL) against the standard wire localization method for guiding breast-conserving surgery in women with non-palpable breast cancer or DCIS. The goal was to see if the BCL could achieve similar or better rates of clea…

This study aimed to find the most effective way to deliver pain-numbing medication (nerve blocks) before a double mastectomy with reconstruction. Researchers compared different injection locations to see which one best reduced patients' need for opioid painkillers after surgery. …

This study involved 775 women who had breast-conserving surgery and radiation for breast cancer. Researchers wanted to see how different surgical and radiation techniques affect breast firmness (fibrosis) and cosmetic outcome. The goal was to find ways to improve appearance and q…

This study looked at how African American women who survived breast cancer react to stress. Researchers measured stress hormones, heart rate, and blood pressure during a stressful task. They also checked how stress relates to diet, exercise, and treatment choices. The goal is to …

This study tested whether an educational video series about sexual health is acceptable and useful for women going through breast cancer treatment. 32 women with early-stage breast cancer watched the videos and gave feedback. The goal was to see if the videos were appropriate and…

This study looked at 27 women with breast cancer who had a mastectomy and immediate breast reconstruction using an implant. The implant was placed either above or below the chest muscle, based on the patient's body and preference. Researchers measured pain, arm function, quality …

This study looked at how breast cancer impacts the lives of 470 women in Paris, comparing those born in France with those born in sub-Saharan Africa. Researchers wanted to understand differences in diagnosis, treatment access, and social effects like family and work. The goal is …

This small study tested whether a green dye called indocyanine green (ICG) can help surgeons locate small, non-palpable breast tumors during surgery. Ten women with early-stage breast cancer took part. The dye was injected near the tumor, and a special camera made the tumor glow,…

This study gave 61 postmenopausal women with early-stage, hormone-sensitive breast cancer a short course of letrozole (1–4 weeks) before their planned surgery. The goal was not to treat the cancer but to measure how much the tumor depends on hormones by checking a marker called K…

This study looked at 110 breast cancer patients to see if arm swelling (lymphedema) is linked to a specific type of muscle pain called myofascial pain syndrome. Researchers measured tender spots in the muscles and compared pain levels between affected and unaffected arms. The goa…

This study looked at 77 women with breast lesions that only show up on special contrast-enhanced mammograms. Doctors wanted to find out the smallest number of tissue samples needed to make a reliable diagnosis. The goal is to make biopsies more efficient and reduce discomfort whi…

This study looked at whether health education can improve lifestyle habits in women being treated for breast cancer. Twenty-eight women took part, with one group getting health advice and the other serving as a control. The goal was to see if education could help them be more act…

This study involved 270 women with early-stage, hormone-receptor-positive breast cancer. Researchers wanted to see how a genetic test called OncotypeDX, which gives a recurrence score, influences doctors' treatment recommendations. They also checked if the score was linked to can…

This study looked at why some women disagree with their personalized breast cancer risk score. Researchers gave 781 Black or African American women their Gail Model risk estimate and asked if they agreed. The goal was to understand this rejection and improve how risk information …

This study tested different methods to encourage more people to get genetic testing for hereditary breast and ovarian cancer risk. Researchers used electronic health records to find over 1,300 eligible patients at Penn Medicine gynecology clinics. They tried sending messages dire…