New Bra-Like device could make breast cancer surgery more precise

NCT ID NCT04397185

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tested a new device called the Breast Cancer Locator (BCL), a custom plastic bra that helps surgeons find tumors during breast-conserving surgery. It was compared to the standard wire localization method in 480 women with non-palpable breast cancer. The goal was to see if the BCL could reduce the rate of positive margins (cancer cells at the edge of removed tissue) and the need for repeat surgeries.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Breast Cancer Locator (BCL) device

What this could lead to

If successful, this device could make breast-conserving surgery more precise, reducing the need for repeat surgeries and improving cosmetic outcomes.

What could go wrong

This is a completed trial comparing a device to standard care, so results are already in. The device may not show significant improvement over wire localization, and benefits may vary by patient.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ductal breast carcinoma in situ female breast carcinoma invasive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Arizona Center for Cancer Care

    Scottsdale, Arizona, 85258, United States

  • Baptist MD Anderson Cancer Center

    Jacksonville, Florida, 32207, United States

  • Basildon University Hospital

    Basildon, United Kingdom

  • Catholic Medical Center

    Manchester, New Hampshire, 03102, United States

  • Cheshire Medical Center

    Keene, New Hampshire, 03431, United States

  • Columbia University Irving Medical Center and New York-Presbyterian Hospital

    New York, New York, 10032, United States

  • Dartmouth-Hitchcock Medical Center

    Lebanon, New Hampshire, 03766, United States

  • Hennepin Healthcare

    Minneapolis, Minnesota, 55415, United States

  • Inova Schar Cancer Institute

    Fairfax, Virginia, 22031, United States

  • Kent Hospital

    Warwick, Rhode Island, 02886, United States

  • LKH Feldkirch

    Feldkirch, Austria

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Manchester University NHS

    Manchester, United Kingdom

  • Mass General/North Shore Center for Outpatient Care

    Danvers, Massachusetts, 01923, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Princess Margaret Cancer Centre

    Toronto, Ontario, M5G 2M9, Canada

  • Rutland Regional Medical Center

    Rutland, Vermont, 05701, United States

  • St. Joseph Hospital

    Nashua, New Hampshire, 03060, United States

  • St. Peter's Hospital

    Albany, New York, 12208, United States

  • Steward Medical Group

    Easton, Massachusetts, 02356, United States

  • Summit Health

    Florham Park, New Jersey, 07932, United States

  • Tufts Medical Center

    Boston, Massachusetts, 02111, United States

  • Women and Infants Hospital

    Providence, Rhode Island, 02905, United States