Scientists create 'Living Biobank' from breast tumors to unlock secrets of drug resistance
NCT ID NCT04133077
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study takes tumor samples from women with aggressive breast cancers (triple-negative or luminal B) and grows them in mice to create patient-derived xenografts (PDX). The goal is to see how well these mouse models mimic the original tumors and to learn about tumor evolution and resistance. About 85 participants will provide blood and tissue samples, but no new treatment is being tested.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help researchers better understand how breast cancers evolve and resist treatment, potentially guiding future therapies.
What could go wrong
This is an early, observational study with no direct benefit to participants. The mouse models may not fully represent human tumors, limiting what can be learned.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Centre Jean PERRIN
RECRUITINGClermont-Ferrand, Puy-de-Dôme, 63011, France
Contact Phone: •••-•••-•••• Email: •••••@•••••