New contrast mammography could spot breast cancer recurrence earlier

NCT ID NCT06105749

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study is testing whether adding a special type of mammogram (contrast-enhanced mammography, or CEM) every two years to the standard yearly 3D mammogram can find new breast cancers in women who have already had breast cancer. The goal is to see if CEM detects more cancers while keeping false alarms low. About 1,500 women aged 30-79 who are at least one year past their breast cancer treatment will participate.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

contrast-enhanced mammography (CEM)

What this could lead to

If successful, this could lead to a more accurate screening method for women who have had breast cancer, catching new cancers earlier with fewer false alarms.

What could go wrong

This is a single-arm study without a control group, so results may not prove superiority over standard screening. Also, CEM requires an IV contrast injection, which carries a small risk of allergic reaction.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm female breast carcinoma neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hillman Cancer Center at Shadyside

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Magee Womancare Monroeville

    RECRUITING

    Monroeville, Pennsylvania, 15146, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Magee-Womens Hospital

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UPMC Magee at the Lemieux Sports Complex

    RECRUITING

    Cranberry Township, Pennsylvania, 16066, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UPMC Magee-Womens Imaging - Bethel Park

    RECRUITING

    Bethel Park, Pennsylvania, 15102, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UPMC West Mifflin Outpatient Center

    RECRUITING

    West Mifflin, Pennsylvania, 15236, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact