Vaginitis

This study compared two common antibiotics—azithromycin (single dose) and doxycycline (7-day course)—for treating anal chlamydia in women who also had a vaginal chlamydia infection. The goal was to see which treatment clears the anal infection better, since anal chlamydia often g…

This study tested whether taking a probiotic called Lactobacillus crispatus LCr86 by mouth could improve vaginal health in women with an intermediate vaginal microbiome. 80 women participated, taking either the probiotic or a placebo for 8 weeks. Researchers measured changes in v…

This study tested whether analyzing a patient's DNA and RNA could help doctors pick the right drug for inflammatory diseases that don't fit standard categories. 32 adults with at least two affected organs (including skin) received one of six targeted therapies based on their mole…

This study tested the safety of using pHyph, a vaginal tablet that naturally restores acidity, for 12 days in 32 adult women with bacterial vaginosis (BV). BV is a common infection causing unpleasant discharge and odor, and often returns after antibiotic treatment. The goal was t…

This study tested whether vaginal capsules containing live lactobacilli (good bacteria) are safe and tolerable for treating bacterial vaginosis (BV), a common infection. Fifty-seven women with BV took either the lactobacillus capsules or the standard antibiotic metronidazole. The…

This study tested whether vaginal probiotic capsules can cure bacterial vaginosis (BV) better than a placebo. 402 women with BV took part. The main goal was to see if more women were cured 21-30 days after treatment with the probiotic compared to placebo. The trial was completed …

This study tested a new oral medication, oteseconazole, to see if it can prevent recurrent yeast infections in women who have had at least three infections in the past year. Over 400 participants took either the study drug or a placebo for 12 weeks after an initial treatment, and…

This study tested whether vaginal capsules containing two types of Lactobacillus probiotics can treat bacterial vaginosis, a common vaginal infection. Sixty-six women received either the probiotic capsule or a placebo. The goal was to see if the probiotics could restore normal va…

This study tested a new oral medication, oteseconazole, to see if it can prevent recurrent yeast infections in women who have had at least three infections in the past year. Participants first received standard treatment for their current infection, then took either oteseconazole…

This study tested a device that uses UVA and blue light to treat bacterial vaginosis and yeast infections. 38 women received one or two light treatments. Researchers checked if symptoms improved and if the vaginal microbiome became healthier. The goal is to find an alternative to…

This study tested two common antibiotics, clindamycin and metronidazole, taken orally for a week to treat abnormal vaginal flora in pregnant women at high risk for preterm labor. The goal was to see which drug better clears the infection and reduces risks like early delivery. 166…

This study tested whether an oral probiotic supplement could help restore healthy bacteria in the vagina. It included 32 women aged 35-43 with vaginal imbalance and fertility concerns. Researchers measured how well the probiotic colonized the body and its effects on immune and an…

This study tested whether adding a vaginal clindamycin cream to standard oral metronidazole works better than oral metronidazole alone for treating bacterial vaginosis. One hundred women with confirmed BV took part. The goal was to see if the combination relieved symptoms like di…

This study tested a gel called Lactal Gel to see how well it treats bacterial vaginosis, a common vaginal infection. Fifty women aged 18 and older used the gel for one week. Doctors checked if the infection cleared and asked about symptoms like odor and itching. The goal was to s…

This study tested a vaginal pessary (Gedea) in 26 women with yeast infections. Participants used the device daily for 6 days. Researchers checked if symptoms like itching and burning went away by day 7 to 14. The goal was to see if the device could safely treat the infection with…

This study looked at how well a new, quick finger-prick test (LumiraDx CRP) measures CRP levels compared to a standard lab test. CRP is a marker of infection, inflammation, or tissue injury. 79 adults with symptoms of these conditions took part. The goal was to see if the new tes…

This study tested whether a rapid point-of-care test (Xpert® Xpress MVP) helps doctors diagnose vaginal infections more accurately than usual methods. 351 women with symptoms like discharge or itching were randomly assigned to either usual care or the rapid test. Researchers then…

This early study tested a new radioactive tracer called 18F-FDS in 16 people with suspected bacterial or fungal infections. The tracer is designed to light up infection sites on PET/CT scans, helping doctors see exactly where an infection is. The goal was to check how the tracer …

This study tested whether giving an antibiotic (clindamycin) to pregnant women with bacterial vaginosis (a common vaginal infection) before 13 weeks of pregnancy could lower the chance of very early preterm birth. Over 3,000 pregnant women took part. The goal was to see if early …

This study tested whether pelvic floor muscle training combined with patient education can improve genital and urinary symptoms in postmenopausal women. Fifty women participated in an 8-week program that included progressive exercises and information sessions. Researchers measure…

This study tested a new treatment for postmenopausal women with vaginal atrophy—a condition causing dryness, burning, and pain. Researchers combined CO₂ laser therapy with a collagen cream to see if it worked better than laser alone. Sixty women aged 35 to 75 took part, and the t…

This study tested whether a daily probiotic (Lactobacillus crispatus M247) combined with vaginal laser therapy can improve vaginal health and reduce symptoms like dryness, itching, and pain in menopausal women with atrophic vulvovaginitis. 75 women were split into two groups: one…

This study tested a new vaginal probe that uses special lights to treat vaginal atrophy in 25 postmenopausal women who had not been helped by other treatments. The probe aims to reduce pain and dryness by stimulating natural tissue repair. The main goal was to check safety and se…

This study tests whether injecting platelet-rich plasma (PRP) from a woman's own blood into the vulvovaginal area can relieve symptoms of genital atrophy like dryness, burning, and pain during sex. It includes 30 women who cannot use standard hormone treatments. Half receive PRP …

This study tested a fractional carbon dioxide laser treatment for women with vaginal and urinary symptoms like dryness, burning, pain during sex, and incontinence. One hundred women received three laser sessions about six weeks apart. The main goal was to see if symptoms improved…

This completed study looked at how the social networks of caregivers affect their stress and health when caring for someone with an inherited disease. Researchers surveyed over 680 participants, including family members and formal caregivers, to understand caregiving burden and s…

This study tested a Portuguese version of the DIVA questionnaire to see if it reliably measures how vaginal aging symptoms (like dryness, itching, or pain) affect daily activities, sex life, emotions, and body image. 300 women with at least one symptom of vulvovaginal atrophy too…

This study gathered information from 32 people with cytolytic vaginosis, a poorly understood condition. Researchers aimed to identify risk factors, common symptoms, and how to diagnose it. They also looked at whether baking soda vaginal washes are an effective treatment. The goal…

This study looked at whether a low-dose vaginal estrogen tablet (Vagifem) is safe for women who have had breast cancer and are taking aromatase inhibitors. 31 postmenopausal women with a history of breast cancer used the tablet for vaginal dryness. Researchers measured their bloo…

This study followed 603 pregnant women in South Africa to see if infections or bacteria in the vagina are linked to how early they give birth. Researchers tested for sexually transmitted infections, yeast, and other germs at the start of pregnancy and again at 30-34 weeks. The go…

This study looked at whether ospemifene, a non-hormonal drug for vaginal dryness, also affects brain activity in postmenopausal women with sexual interest-arousal disorder. Twenty-five women took the drug or a placebo and underwent brain scans while watching sexual videos or smel…