Vulvovaginitis
MONDO:0007019An inflammatory pathologic process that affects the vulva and the vagina.
26 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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New gel could tackle stubborn yeast infections
Disease control Recruiting nowThis study tests a new gel called OCF001 for treating acute yeast infections in women. About 36 women with a confirmed yeast infection will use the gel or a placebo for 7 days. Researchers will check if the infection clears up and if the gel is safe and well-tolerated.
Phase: PHASE2 • Sponsor: Sano Chemicals Inc • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Natural prebiotic could beat antibiotics for thrush and BV
Disease control Recruiting nowThis study tests whether lactoferrin, a natural prebiotic from cow's milk, can be a good alternative to antibiotic tablets for women with bacterial vaginosis (BV) or thrush. Researchers will recruit 114 women and give half lactoferrin vaginal pessaries for 3 weeks, while the othe…
Phase: NA • Sponsor: Guy's and St Thomas' NHS Foundation Trust • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Could a contraceptive gel ward off vaginal infections?
Disease control Recruiting nowThis early study tests whether a lactic acid gel (Phexxi) used twice weekly can change the vaginal microbiome to help prevent recurrent bacterial vaginosis and yeast infections. 22 premenopausal women with a history of these infections will use the gel for 4 weeks. Researchers wi…
Phase: EARLY_PHASE1 • Sponsor: Queen's Medical Center • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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Cooling device may soothe yeast infections without drugs
Disease control Recruiting nowThis study is testing a new cooling device placed in the vagina to treat yeast infections. Researchers want to see if it can relieve symptoms and clear the infection within 7 days. The study involves 55 women aged 22-49 with uncomplicated yeast infections. It is an early-stage tr…
Phase: NA • Sponsor: Coologics, Inc • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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New gel aims to stop recurring vaginal infections
Disease control Recruiting nowThis study tests a gel device called Multi-Gyn FemiTotal in 80 women with bacterial vaginosis or vaginal yeast infections. Participants use the gel for 7 days, and if symptoms clear, they are followed for 4 months to see if the infection returns. The goal is to see if the gel can…
Phase: NA • Sponsor: Karo Pharma AB • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Fast new swab test could speed up vaginitis diagnosis
Diagnosis Recruiting nowThis study will test a new diagnostic device called the Nanopath assay, which aims to quickly detect bacteria or yeast causing vaginitis. Up to 1000 women with symptoms like itching or discharge will provide vaginal swab samples, either collected by a clinician or themselves. The…
Sponsor: Nanopath, Inc • Aim: Diagnosis
Last updated Jul 22, 2026 00:00 UTC
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Could a probiotic boost yeast infection treatment?
Symptom relief Recruiting nowThis study tests whether adding a probiotic supplement (Bioithas WOMAN®) to standard antifungal medicine helps relieve symptoms of vaginal yeast infections faster. About 60 women with suspected yeast infections will take either antifungal treatment alone or with the probiotic for…
Phase: NA • Sponsor: Bioithas SL • Aim: Symptom relief
Last updated Jun 27, 2026 12:36 UTC
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New study aims to unlock secrets of common vaginal problems
Knowledge-focused Recruiting nowThis study is creating a data bank to better understand vaginal conditions like vulvodynia, yeast infections, bacterial vaginosis, and preterm labor. Researchers will look at proteins, immune markers, and vaginal bacteria in 550 women, including healthy volunteers and those with …
Sponsor: Texas Tech University Health Sciences Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Can a simple swab predict surgical wound trouble?
Knowledge-focused Recruiting nowThis study checks if having a vaginal infection before vulvar surgery raises the risk of wound infections or breakdown. About 91 adults with non-cancerous vulvar conditions will be tested with a swab on surgery day. Researchers will follow up by phone at 1 week and a clinic visit…
Phase: NA • Sponsor: University of Virginia • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC