Spinal stenosis

This trial studies a device called coflex, a small implant placed in the spine after decompression surgery for lumbar spinal stenosis (a narrowing of the spinal canal that causes back and leg pain). The study includes 40 adults with moderate to severe stenosis and low back pain. …

This study tested a new way to set the breathing machine during back surgery. Instead of using standard settings, doctors adjusted the machine based on how stiff the patient's lungs were. The goal was to see if this approach could reduce lung problems after surgery. The study inv…

This study followed 77 adults who received spinal implants (PASS LP, PASS DEGEN, or PASS TULIP PRIME) to treat degenerative spine conditions like disc degeneration or spinal deformity. The main goal was to see if the bones fused properly after 24 months. Researchers also tracked …

This study tested a new gel-like product that helps stop bleeding during spinal surgery. It was compared to an existing product in 130 patients with spinal stenosis, tumors, or injuries. The goal was to see if the new product works just as well and is safe to use.

This study tested a new plate system used during spine fusion surgery in 75 adults with conditions like degenerative disc disease or scoliosis. The goal was to see if the plate is safe and helps bones fuse together properly. Researchers measured pain relief and fusion success ove…

This study looked at how safe and well a new spinal implant (Modulus ALIF System) works in 123 adults having back surgery. The patients had conditions like worn-out discs or slipped vertebrae. The main goals were to check for complications and see if the bones fused properly afte…

This study tested a Turkish version of the Johns Hopkins In-Room Independence Scale, which measures a patient's ability to move, use the toilet, and think clearly while in their hospital room. Researchers worked with 100 adults who had conditions like stroke, Parkinson's, or ampu…

This pilot study tested whether a one-day Acceptance and Commitment Therapy (ACT) workshop, plus a follow-up phone call, could help prevent chronic pain after back surgery. 45 adults scheduled for spinal surgery took part. The study focused on whether the workshop was acceptable …

This study tested a new gel called Collabarrier® to see if it can prevent scar tissue from forming after back surgery for herniated discs or spinal stenosis. Sixty-nine adults having their first back surgery were randomly given either the new gel or an existing one. Researchers c…

This study looked at whether a lumbar epidural steroid injection can reduce restless legs syndrome symptoms in 45 adults with lumbar central spinal stenosis. Participants received a standard injection as part of routine care, and their restless legs severity, pain, disability, an…

This study tested two physical therapy techniques—nerve flossing and deep neck flexor strengthening—in 62 adults with cervical spinal stenosis. The goal was to see which method better reduces pain, improves neck movement, and helps with daily activities. Participants did their as…

This study tested whether adding dexamethasone or dexmedetomidine to a standard nerve block (erector spinae plane block) could extend pain relief after spine surgery. 90 adults undergoing lumbar spine surgery received one of the two additives or a placebo. The main goal was to se…

This study tested a 6-week program that combines specific exercises with education to see if it improves walking ability in people with lumbar spinal stenosis and nerve-related leg pain. Fifty-one adults aged 50 and older took part. The intervention group received both exercises …

This study compared a newer, less invasive endoscopic surgery to standard open surgery for people with lumbar spinal stenosis, a condition that causes back and leg pain. 36 adults who needed surgery were randomly assigned to one of the two procedures. Researchers measured pain, w…

This study tested whether giving acetaminophen (Tylenol) through an IV works better than pills for pain after lumbar spine surgery. 166 adults having a specific type of back fusion surgery were randomly assigned to receive either IV or oral acetaminophen. The goal was to see if t…

This study looked at different rehabilitation programs for 90 adults who had back surgery for degenerative lumbar disease. The goal was to see which rehab approach best reduces nerve pain, helps patients regain function, and improves quality of life. Participants were randomly as…

This study compared two pain relief methods for people undergoing lower back decompression surgery. One group received a nerve block (erector spinae plane block), while the other received ketamine through an IV. Researchers measured how well patients recovered using a quality-of-…

This study compared two surgical approaches for people with a single level of lumbar spinal stenosis (a narrowed spine canal causing leg pain and trouble walking). 96 adults aged 40-75 were randomly assigned to receive either minimally invasive decompression and fusion or traditi…

This study compared two procedures for relieving pain from lumbar spinal stenosis, a common cause of back and leg pain in older adults. One group received a newer technique called erector spinae plane block, while the other got a standard caudal epidural steroid injection. Resear…

This study tested whether Opalmon tablets can improve symptoms and physical function in 107 adults with acquired lumbar spinal stenosis, a condition where the spinal canal narrows and causes leg pain when walking. Participants took the medication for 8 weeks, and researchers meas…

This study tested whether adding the steroid dexamethasone to a standard nerve block could reduce pain and inflammation after lumbar laminectomy (back surgery). Thirty-six adults undergoing surgery received either the nerve block with dexamethasone or without. The dexamethasone g…

This study looked at two types of surgery for people over 50 with a slipped vertebra (spondylolisthesis) and a narrowed spine canal (stenosis). One group had a smaller surgery to take pressure off the nerves (decompression alone), while the other had that plus a fusion with metal…

This study tested a new device called Ceragem Master V6 that gently stretches the spine in people with herniated discs or spinal stenosis. 60 adults were randomly assigned to use the new device or standard physical therapy. The goal was to see if the device could improve spine st…

This small study tested whether a spinal cord stimulator can reduce back and leg pain in people with lumbar spinal stenosis caused by epidural lipomatosis (fatty tissue buildup). Three adults with chronic pain received the device and were followed for 6 weeks. The main goal was t…

This study looked at how common muscle and posture problems are in physiotherapy students and whether a special physiotherapy program could help. 44 students with back pain and muscle tightness received treatments like trigger point release, stretching, and joint mobilization. Th…

This completed study looked at 90 people with lower back pain from conditions like herniated discs or spinal stenosis. Researchers compared two different target areas for injecting numbing medicine during a lumbar spine block to see which provides better pain relief and blood flo…

This study tested whether a specific nerve block, called an erector spinae plane block, can lower the amount of morphine patients need after lumbar spine surgery. 100 adults having surgery for herniated discs or spinal stenosis were included. The block is given under ultrasound g…

This study looked at whether wearing a back brace after spinal fusion surgery improves pain and quality of life. 43 adults with degenerative spine conditions were randomly assigned to wear a brace or not. Researchers measured disability, pain, and general health at 6 weeks and 3 …

This study looked at whether letting patients control their own sedation during arm surgery under regional anesthesia leads to higher satisfaction compared to having an anesthesiologist control it. 70 adults having upper limb orthopedic surgery were randomly assigned to either pa…

This study compared two ultrasound-guided pain blocks—caudal block and quadratus lumborum plane block—in 111 adults undergoing lumbar spine surgery. The goal was to see which provides better pain relief and reduces the need for opioid painkillers. Researchers measured how long it…

This pilot study tested whether using ultrasound to guide pharmacopuncture (herbal injections) is safe and effective for neck and back pain. Fifty adults with spinal disorders received the treatment, and researchers tracked side effects, pain levels, disability, and quality of li…

This study tested whether an injection of amniotic fluid, a natural anti-inflammatory, works better than a standard steroid injection for chronic back and leg pain caused by spinal stenosis. Sixty-one adults who had not improved with other treatments were randomly assigned to rec…

This study translated the Generic Functional Index, a questionnaire that measures how well people can do daily activities, into Turkish. Researchers tested it with 200 adults who have muscle or joint problems to see if it is accurate and reliable. The goal is to give Turkish-spea…

This study gathered information from 193 adults who had surgery or orthopedic treatment for spine problems. Researchers collected clinical, functional, and social data to create a detailed database. The goal was to better understand patient outcomes and standardize how data is co…

This study looked at 120 adults with neck or lower back spine issues to compare two types of scans: contrast-enhanced MRI and FDG-PET/CT. Researchers checked how clear the images were and whether the scans caused any short-term changes in kidney function or blood counts. The goal…

This completed study looked at how the skeleton is aligned with gravity in adults with postural problems. Researchers used a low-dose X-ray device called EOS to create 3D images of the spine and pelvis. The goal was to better understand the body's geometry in people with balance …

This study looked at 20 people with lumbar spinal stenosis (a narrowing in the spine that can cause leg pain when walking) who were waiting for surgery. Researchers measured their walking patterns and asked about pain, function, and quality of life before and after the operation.…

This pilot study tested whether a larger trial is possible comparing two standard surgeries for lumbar spinal stenosis with a related condition called spondylolisthesis. The two procedures are decompression alone and decompression with fusion. The study enrolled 70 surgical candi…

This study explored how frailty affects people with lumbar spinal stenosis, a common age-related back condition. Researchers measured pain, balance, disability, fear of falling, and quality of life in 91 participants aged 45-80. The goal was to better understand frailty in this g…

This completed study from Turkey examined 81 adults aged 45–80 with lumbar spinal stenosis—a condition that causes back and leg pain when walking. Researchers measured pain, disability, sleep quality, depression, and a condition called central sensitization (where the nervous sys…

This study tested a new lightweight device called PYTHEAS ODYSSEE that helps surgeons place screws in the spine more accurately. Fourteen adults having spine surgery used the device to guide screw placement. The goal was to see if the device reduces screw misplacement and is safe…

This study looked at three different ways to close surgical wounds after spine surgery. Researchers measured blood flow around the wound to see if one method was better. The study involved 50 adults with spinal stenosis who had back surgery at Mayo Clinic.

This study looked at whether manual therapy, exercise, and acupuncture can reduce pain and improve walking in older adults with lumbar spinal stenosis, a common cause of back and leg pain. Researchers enrolled 60 participants to see if a larger trial is possible. The goal is to f…

This study looked back at 25 years of medical records from 246 patients aged 50+ with lumbar spinal stenosis (a narrowing in the spine that can cause leg pain and trouble walking). Researchers compared patients who had a less invasive surgery (tubular decompression, with or witho…

This study tested whether specially trained physiotherapists can safely diagnose and treat non-urgent muscle and joint pain in the emergency room, compared to standard care from doctors. 102 patients with back, neck, or shoulder pain were randomly assigned to either a physiothera…

This study looked at 50 people with lumbar spinal stenosis to see if simple decompression surgery or a more complex fusion surgery leads to better outcomes. Researchers measured pain, disability, quality of life, and movement using questionnaires and wearable sensors. The goal wa…

This study looked at 72 people with lumbar stenosis who had decompression surgery to relieve leg and back pain. Researchers wanted to see if the surgery also improved their posture, specifically a forward-leaning stance. They used special X-ray imaging to measure changes in spine…

This study looked at 39 people having lower back surgery for a herniated disc or spinal stenosis. Researchers checked for nerve pain before surgery and again 1, 3, 6, and 12 months after using a simple questionnaire. The goal was to see how common nerve pain is after surgery and …

This study looked at 40 adults with lumbar spinal stenosis (a narrowing in the spine that causes pain and trouble walking) who were scheduled for surgery. Researchers measured how fast they could walk before and after the operation using a 6-minute walk test. The goal was to see …

This study used MRI scans to measure the volume of spinal fluid in 40 adults before they received spinal anesthesia for surgery. Researchers wanted to see if the amount of fluid affected how high and how long the anesthesia worked. The goal is to help doctors tailor anesthesia do…

This study collected information from over 8,000 people who had spine surgery for conditions like degeneration, deformity, or trauma. Researchers gathered X-ray and health data to learn which treatments work best for different patients. The goal was to build a database to answer …

This study tested whether having spine surgery patients wear an Apple Watch could help doctors track their recovery. 255 adults wore the watch before and after surgery to measure steps and distance. The goal was to see if this data matched how patients felt and if it could improv…

This completed study compared how well people with complex regional pain syndrome (CRPS), people with other muscle or bone pain, and healthy individuals can imagine movements. Researchers used a questionnaire called the MIQ-RS to measure motor imagery skills. The goal was to see …

This completed study followed 100 patients who had outpatient neck surgery for cervical stenosis, a condition where the spinal canal narrows. Researchers tracked neurologic function, pain, and complications over about 2.5 years. The goal was to see if performing this complex surg…

This study looked at 120 people aged 50 and older with low back pain to see how well MRI-based grading of lumbar spinal stenosis matches what patients report on disability and pain questionnaires. Researchers compared three common questionnaires (Oswestry Disability Index, Istanb…

This completed study with 92 people tested whether a measure called perfusion index (a way to check blood flow) can predict how well a nerve block (erector spinae plane block) relieves chronic neck pain from conditions like herniated discs or spinal narrowing. Researchers tracked…

This study surveyed 116 adults with chronic pain at a rehabilitation clinic to understand how their pain beliefs, spiritual well-being, and attitudes toward complementary and alternative medicine are related. Participants filled out several questionnaires about their pain, mood, …

This study reviewed the records of 978 adults who had spinal fusion surgery to see how often routine follow-up X-rays led to additional tests or changes in treatment. The goal is to find out whether these X-rays are truly helpful or if they can be skipped. The results could help …