Spine surgery pain relief: which additive works best?

NCT ID NCT06233617

Completed Symptom relief Sponsor: Poznan University of Medical Sciences Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding dexamethasone or dexmedetomidine to a standard nerve block (erector spinae plane block) could extend pain relief after spine surgery. 90 adults undergoing lumbar spine surgery received one of the two additives or a placebo. The main goal was to see how long it took before patients needed opioid painkillers. The results could help improve pain management and reduce opioid use after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Dexamethasone and dexmedetomidine (added to a local anesthetic nerve block)
What this could lead to: If one drug works better, it could help patients stay pain-free longer after spine surgery and reduce the need for strong painkillers like opioids.
What could go wrong: This is a small, single-center study with 90 people. The results may not apply to everyone, and the drugs may not show a meaningful difference in pain relief.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

spinal stenosis vertebral column disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ERECTOR SPINAE PLANE BLOCK SPINAL FUSION SPINAL STENOSIS SPINE DISEASE

Contacts and locations

Locations

Poznan University of Medical Sciences

Poznan, Poznań, 61-701, Poland

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