SPINAL STENOSIS

This study looks at how well a spine implant (VIPER PRIME/Expedium) combined with a special bone graft putty (Fibergraft BG) helps bones fuse together after spine surgery. About 100 adults with spine problems like slipped vertebrae or disc degeneration will be followed for two ye…

This early-stage study tests whether a new drug called EC5026 is safe and can reduce nerve pain in people with spinal cord injury. About 36 adults with pain from traumatic or non-traumatic spinal cord injury will take either the drug or a placebo daily for 14 days. Researchers wi…

This study tests a noninvasive device that gently stimulates a nerve in the ear to help people wake up faster after surgery. Researchers will also see if it reduces confusion and depression after the operation. The study involves 40 adults having lumbar spine surgery.

This study tests two different nerve blocks to see which one works better for pain after single-level lumbar disc surgery. 70 adults will receive one of the blocks before surgery, and their pain and opioid use will be tracked for 24 hours. The goal is to find a more effective way…

This study tests whether taking a special probiotic (OMNi-BiOTiC® Hetox) can improve healing, reduce pain, and lower complications after neurosurgery for back or neck problems. About 110 adults having spine surgery will be randomly assigned to receive either the probiotic or a pl…

This study tests whether a specific nerve block (erector spinae plane block) can lower the amount of strong pain medicine patients need after minimally invasive lower back surgery. About 48 adults having a one-level lumbar fusion will be randomly assigned to receive the block or …

This study tests whether giving a single dose of the steroid dexamethasone just before minimally invasive spine fusion surgery can lower back pain afterward and reduce the need for strong painkillers like morphine. Sixty adults aged 50–80 having one- or two-level spine fusion wil…

This study tests whether changing the pulse-width of electrical stimulation during pedicle screw placement affects nerve response thresholds. Researchers will stimulate screws with three different pulse-widths (0.4, 0.2, and 0.05 milliseconds) and record the intensity needed to t…

This registry is following 450 adults undergoing spine fusion surgery who receive an OssDsign bone graft substitute. The goal is to see how well the bones fuse together and how patients' quality of life changes over time. It is an observational study, meaning no new treatment is …

This study follows 15,000 people with various spinal conditions (like stenosis, fractures, infections, or cancer spread) to see how their quality of life changes over 5 years. Participants fill out questionnaires about their health and daily activities. The goal is to understand …

This study is tracking 561 people who have already had spine surgery using METROSAN spinal implants and BONEGRAFT bone fillers. Researchers want to see how well these devices work and if any new safety issues pop up over a year. It's an observational study, meaning patients get s…

This study compares two surgical approaches for single-level lumbar spinal stenosis: decompression alone versus decompression with spinal fusion. Researchers will track 86 patients aged 45-75 over two years to see if the simpler procedure works just as well. The goal is to determ…

This study is building a database of information from 300 adults who have had spine surgery using a special device called the Implanet Jazz System. The goal is to collect measurements like pain levels and quality of life to help doctors learn more and improve future treatments. P…