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One shot before back surgery may cut painkiller need

NCT ID NCT06367855

Recruiting now Symptom relief Sponsor: Potsawat Surabotsopon Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether giving a single dose of the steroid dexamethasone just before minimally invasive spine fusion surgery can lower back pain afterward and reduce the need for strong painkillers like morphine. Sixty adults aged 50–80 having one- or two-level spine fusion will be randomly assigned to receive either dexamethasone or a placebo (salt water) before surgery. Researchers will measure pain scores and morphine use for up to 24 hours after the operation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Dexamethasone
What this could lead to
If it works, this could give surgeons a simple, low-cost way to reduce pain and opioid use after spine surgery.
What could go wrong
This is a small, early-phase trial with only 60 participants, so results may not apply to everyone. Dexamethasone can raise blood sugar and infection risk.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

intervertebral disk degenerative disorder Klippel-Feil syndrome lumbar disk degenerative disorder lumbar spinal stenosis spinal stenosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DISC DEGENERATION DISC DISEASE FUSION OF SPINE SPINAL STENOSIS LUMBAR SURGERY

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Thammasat university hospital

    RECRUITING

    Pathum Thani, Changwat Pathum Thani, 12120, Thailand

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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