Skin infection

This study tests whether a newer antifungal cream (luliconazole) works better than the standard treatment (ketoconazole) for pityriasis versicolor, a common fungal skin infection that causes light or dark patches. About 86 adults with the infection will use one of the two creams …

This study compares the standard antifungal drug itraconazole alone versus itraconazole combined with isotretinoin (an acne medication) in adults with tinea corporis or cruris (ringworm of the body or groin). The goal is to see if the combination shortens treatment time and impro…

This early-stage trial tests a new topical film called ZYG24004 for athlete's foot (tinea pedis). About 64 adults with the infection will apply the film to their feet once or twice. The main goals are to check safety, how the body processes the drug, and whether it can clear the …

This study compares two common antibiotic combinations—vancomycin with piperacillin/tazobactam versus vancomycin with meropenem—to see which is less harmful to the kidneys. About 852 hospitalized adults with serious infections will be randomly assigned to one of the two combos. T…

This study tests whether wearing compression stockings alone can prevent repeat episodes of erysipelas (a bacterial skin infection) as well as the usual approach of antibiotics plus stockings. About 200 adults who have had at least two infections in the same leg will be randomly …

This early-phase trial will test different ways of using permethrin cream to treat scabies in 68 infants and children aged 1 month to 4 years. The goal is to see which strategy works best to kill the mites and relieve itching. Researchers will check skin scrapings under a microsc…

This Phase 2 trial tests a new gel (AP4500) containing the antifungal drug terbinafine for mild to moderate toenail fungus. About 200 adults will apply the gel once or twice daily for 48 weeks. Researchers will compare it to a placebo and an existing treatment (Jublia) to see if …

This study compares two treatments for pityriasis versicolor, a fungal skin infection that causes discolored patches. One group will apply a clotrimazole cream twice daily for two weeks, while the other takes itraconazole pills daily for five days. The trial aims to see which app…

This study tests whether narrow-band ultraviolet B (NB-UVB) light therapy can help people with ringworm infections that don't get better with standard antifungal drugs. The trial will enroll 36 adults who have had at least two relapses in the past six months. Half will receive UV…

This study tests a cream called terbinafine hydrochloride for treating fungal ear infections (otomycosis). About 50 adults with symptoms like itching, pain, and discharge will have the cream applied in the ear every two days for two weeks. The goal is to see if the cream clears b…

This large study in Fiji tests whether a new combination of drugs (moxidectin plus two others) can safely treat three common parasitic infections: lymphatic filariasis, scabies, and strongyloidiasis. About 5,100 people will receive either the new combo or the standard treatment o…

This study tests whether a mobile app using artificial intelligence can help frontline health workers in sub-Saharan Africa better diagnose skin-related neglected tropical diseases, like leprosy and scabies. Researchers will collect images from dermatologists to train the AI, the…

This study tested whether taking a cistanche supplement for 8 weeks, along with a supervised training program, improves anaerobic exercise performance and recovery in young men. 56 men aged 18-25, either elite or amateur athletes, were randomly assigned to receive cistanche extra…

Cellulitis is a painful bacterial skin infection. This study tests whether adding naproxen (an anti-inflammatory drug) to standard antibiotics helps reduce redness and pain faster than antibiotics alone. About 884 adults with cellulitis will take either naproxen or a placebo for …

This study tests whether Xdemvy eye drops can reduce eyelash mite irritation and improve comfort for people who wear special scleral lenses. Five adult lens users with moderate to severe Demodex blepharitis will use the drops and report changes in symptoms like dryness, itching, …

This study tests whether a probiotic called Lactiplantibacillus plantarum Dad-13, originally from buffalo milk curd, can improve gut health and physical performance in 30 adolescent athletes. Participants will take the probiotic and have their gut bacteria, inflammation markers, …

This study looks at whether using ketoconazole 2% shampoo for seven days works better than using it for three days to treat pityriasis versicolor, a common fungal skin condition that causes discolored patches. About 76 people aged 12 and older with confirmed infection will be ran…

This observational study will look at 10,000 adults in intensive care units (ICUs) around the world during a single 24-hour period. Researchers want to find out how common infections and antibiotic-resistant bacteria are, how they are treated, and how patients recover. No new tre…

This study looks at how muscle tiredness changes the way female volleyball players move their legs when landing on one foot. Researchers will use smartphone videos to measure hip, knee, and ankle motion in 35 athletes. The goal is to understand injury risks better, not to test a …

This research project aims to understand why older adults get more infections and why those infections can be more serious. By following 23,000 people aged 60 and older, scientists will collect health data and samples like blood and stool to study how the immune system changes wi…

This study looks at how people with skin conditions (like eczema, psoriasis, or skin cancer) manage stress, feel lonely, and bounce back from challenges. Researchers will compare 375 adults with and without skin disease across 15 European countries using questionnaires. The goal …

This study looks at how body composition (like fat and muscle) and metabolism (how the body uses energy) are connected in adult and older Filipino athletes. Researchers will measure things like body fat, muscle mass, resting energy use, and fitness levels in 120 athletes and non-…

This study looks at whether professional e-sports players are more physically fit than amateur players. Researchers will measure reaction time, endurance, and grip strength in 40 adults aged 18 to 30. The goal is to understand how different levels of gaming affect physical health…

This study looks at how certain immune cells, called MAIT cells, behave in people with hidradenitis suppurativa (HS), a painful skin condition. Researchers will take skin and blood samples from 45 adults with HS and compare them to samples from people with other skin diseases. Th…

This study will collect blood samples from 30,000 adults in the UK with various health conditions, including blood clots, infections, heart disease, diabetes, and more. The samples will be used to develop and fine-tune new diagnostic tests for the cobas® lumira device, which allo…

This study will follow 300 adults with severe infections in the ICU to see how levels of specialized pro-resolving mediators (SPMs)—natural molecules that help stop inflammation—change over time. Researchers will use blood samples already collected during routine care, so no extr…