Compression stockings may let patients skip Long-Term antibiotics for recurring skin infections
NCT ID NCT07549594
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether wearing compression stockings alone can prevent repeat episodes of erysipelas (a bacterial skin infection) as well as the usual approach of antibiotics plus stockings. About 200 adults who have had at least two infections in the same leg will be randomly assigned to one year of either compression therapy alone or compression plus daily oral penicillin. If compression alone works, it could spare patients from long-term antibiotic use and its side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Phenoxymethylpenicillin (oral penicillin) and compression stockings
- What this could lead to
- If compression alone works as well as antibiotics plus compression, patients could avoid long-term antibiotics and their side effects.
- What could go wrong
- This is a Phase 4 trial with 200 participants, so results may not apply to everyone. Compression alone might not prevent infections as effectively as the combination.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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AMIENS
Amiens, France
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Bordeaux-D
Bordeaux, France
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Bordeaux-I
Bordeaux, France
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CRETEIL
Créteil, France
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DIJON
Dijon, France
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GRENOBLE
La Tronche, France
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LE MANS
Le Mans, France
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LYON
Lyon, France
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La Reunion
Saint-Pierre, France
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Lille Ghicl
Lille, France
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NANTES-D
Nantes, France
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NANTES-I
Nantes, France
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ORLEANS
Orléans, France
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POITIERS
Poitiers, France
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Paris Cognacq-Jay
Paris, France
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Paris La Pitie
Paris, France
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Paris St Louis-I
Paris, France
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Paris St-Antoine-I
Paris, France
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REIMS
Reims, France
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RENNES-D
Rennes, France
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ROUEN
Rouen, France
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St-Etienne
Saint-Etienne, France
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Strasbourg
Strasbourg, France
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TOURS-D
Chambray-lès-Tours, France
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TOURS-I
Tours, France