Could a common acne drug help beat tough fungal infections?
NCT ID NCT07675239
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This study compares the standard antifungal drug itraconazole alone versus itraconazole combined with isotretinoin (an acne medication) in adults with tinea corporis or cruris (ringworm of the body or groin). The goal is to see if the combination shortens treatment time and improves cure rates. Participants take either itraconazole daily or itraconazole plus isotretinoin daily, and are monitored for side effects and infection clearance.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Itraconazole and isotretinoin
What this could lead to
If the combination works, it could offer a faster, more effective treatment for hard-to-cure fungal skin infections.
What could go wrong
This is a small, early-phase trial with only 60 participants. Isotretinoin has side effects like dry skin and liver changes, and the combo may not prove better than itraconazole alone.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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PakEmirates
Rawalpindi, Punjab Province, 46000, Pakistan
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••