Could a common acne drug help beat tough fungal infections?
NCT ID NCT07675239
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This study compares the standard antifungal drug itraconazole alone versus itraconazole combined with isotretinoin (an acne medication) in adults with tinea corporis or cruris (ringworm of the body or groin). The goal is to see if the combination shortens treatment time and improves cure rates. Participants take either itraconazole daily or itraconazole plus isotretinoin daily, and are monitored for side effects and infection clearance.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Itraconazole and isotretinoin
- What this could lead to
- If the combination works, it could offer a faster, more effective treatment for hard-to-cure fungal skin infections.
- What could go wrong
- This is a small, early-phase trial with only 60 participants. Isotretinoin has side effects like dry skin and liver changes, and the combo may not prove better than itraconazole alone.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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PakEmirates
Rawalpindi, Punjab Province, 46000, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.