Radiculopathy

This study looks at a special putty called Fibergraft used in spine surgery to help bones grow together. About 80 adults with back pain or nerve problems from spine issues will get this putty during surgery. Doctors will check how well the bones heal using CT scans and ask patien…

This study tests a new way to inject numbing medicine directly into a specific nerve root to find out which nerve is causing back and leg pain. The goal is to see if this method is safer and more accurate than current techniques. About 80 adults with sciatica who are scheduled fo…

This study compares two manual therapy techniques—myofascial release and post-isometric relaxation—for treating piriformis syndrome, a condition where a muscle in the buttock presses on the sciatic nerve, causing pain, numbness, and tingling. Twenty-six adults aged 20 to 50 with …

This phase 3 trial tests whether a cannabis extract called VER-01 can reduce leg pain in people with chronic nerve root compression (sciatica-like pain) who haven't gotten enough relief from standard painkillers. About 810 participants will receive either VER-01 or a placebo for …

This study tests whether a specialized acupuncture technique called 'Three-Needle Dazhui' combined with electroacupuncture can reduce pain and improve daily function better than standard electroacupuncture alone. The trial will involve 74 adults with cervical spondylotic radiculo…

This study looks at whether adding a technique called neural flossing to a standard spinal mobilization can better relieve pain and disability in people with lumbar radiculopathy (a pinched nerve in the lower back causing leg pain). Thirty-six adults aged 30-50 with radiating leg…

This study will track 600 adults with neck or back pain who are already scheduled to receive pharmacopuncture (herbal medicine injections) as part of their care. The key difference is that doctors will use an ultrasound device to guide the needle, aiming to avoid nerves and blood…

This study compares a specialized posture-correction exercise program (Mirror Image Spine Correction) with standard physiotherapy for adults with sciatica. Over 12 weeks, 64 participants will receive supervised sessions three times per week. The main goal is to see if the new exe…

This study compares two non-invasive nerve stimulation techniques—TENS (electrical pads on the skin) and rTMS (magnetic pulses on the scalp)—for reducing pain and improving function in people with cervical radiculopathy (a pinched nerve in the neck causing arm pain). Fifty adults…

This study tests whether a gentle electrical stimulation of the ear (taVNS) given before a standard epidural steroid injection can improve pain relief for people with cervical radiculopathy—a pinched nerve in the neck causing arm pain. Eighty adults will be randomly assigned to r…

This study tests whether Tecar therapy, a non-invasive device that delivers high-frequency electromagnetic energy to deep tissues, can reduce pain and disability in people with lumbar radiculopathy (sciatica). Ninety adults with recent-onset symptoms will be randomly assigned to …

This study looks at whether different doses of steroid injections work equally well for treating sciatica (nerve pain in the lower back and leg). About 150 adults with MRI-confirmed lumbar radiculopathy who have not had back surgery will receive one of several doses of either tri…

This study will test whether a gentle nerve-sliding technique can reduce pain, improve function, and help balance in people with chronic leg pain from a pinched nerve in the lower back (lumbar radiculopathy). Twenty-eight adults with symptoms lasting 3 to 18 months will receive e…

This study compares two drugs, gabapentin and oxcarbazepine, for treating chronic nerve pain in children aged 8 to 18. Sixty participants will receive one drug or the other in a blinded fashion, with the option to switch if pain doesn't improve. The goal is to see which drug redu…

This study tests whether adding nerve gliding exercises to standard rehab can reduce pain and improve neck movement, grip strength, and quality of life in people with cervical radiculopathy (a pinched nerve in the neck). The trial plans to enroll 28 adults with disc bulges at spe…

This study tests whether a continuous nerve block placed by the surgeon during back surgery can reduce pain and the need for opioids afterward. One hundred adults having lumbar spine surgery will be randomly assigned to receive either the nerve block with a numbing medicine or a …

This study looks at people with a single herniated disc in the lower back who are getting laser disc surgery. Some will also receive a steroid injection during the same procedure. Researchers will track pain, daily function, and need for more treatments to see if the extra inject…

This study compares two non-invasive treatments—high-power laser and pulsed electromagnetic therapy—for reducing pain and improving nerve function in people with lumbar radiculopathy (sciatica from a herniated disc). Sixty participants aged 55-68 will receive one of the therapies…

This study will test whether applying neck traction at different angles, combined with gentle nerve mobilization exercises, can reduce pain and improve function in people with cervical radiculopathy (a pinched nerve in the neck). Forty-five adults aged 30 to 45 with confirmed ner…

This study looks at whether combining kinesio tape with specific neck exercises can improve how well people with cervical radiculopathy sense their neck position, and whether it also reduces pain and improves function. Sixty adults aged 35-50 with chronic neck pain and nerve symp…

This study tests whether TECAR therapy, a deep heat treatment using radiofrequency, can improve proprioception (body awareness) in people with cervical radiculopathy. Eighty adults aged 30-40 with confirmed nerve root compression will be randomly assigned to real or sham TECAR. T…

This study tests whether a gentle, hands-on movement technique applied to the non-painful side can reduce pain and disability in people with cervical radiculopathy (nerve pain in the neck and arm). It includes 40 adults who will receive a single session of this technique. The goa…

This study tests whether acupuncture can safely reduce arm pain caused by cervical spondylotic radiculopathy, a condition where a nerve in the neck is compressed. Researchers will compare real acupuncture to a sham version in 168 adults over 6 weeks, then follow them for 6 months…

This study looks at 96 adults with lower back pain to see if the damage shown on an MRI matches how much pain they actually feel. Participants will fill out pain and disability questionnaires and get a physical exam. The goal is to help doctors better understand and treat back pa…

This study will follow 120 adults receiving a steroid injection for lower back and leg pain caused by a slipped disc. Researchers want to see how factors like anxiety, pain during the procedure, and sedation affect how satisfied patients feel one hour after the injection. The goa…

This study will follow 120 adults with sciatica from a herniated disc who receive a standard steroid injection. Researchers want to see if the speed and pattern of pain relief in the first few days and weeks can predict whether the treatment is still working at 3 and 6 months. Pa…

This study looks at how neck pain and muscle strength relate to walking symmetry in 61 adults aged 40-50 with cervical radiculopathy (a pinched nerve in the neck). Researchers will measure pain, disability, muscle strength, and walking patterns using special mats and devices. The…

This study looks at how neck muscle endurance relates to the ability to sense head position in people with cervical radiculopathy (a pinched nerve in the neck causing pain and arm symptoms). Researchers will test 80 adults aged 20-60 using a device to measure neck movement accura…

This study will check how well standard X-rays and MRIs can spot common spinal bone variations (transitional vertebrae) and correctly identify the disc that is causing pain. Researchers will look at scans from 250 adults with back and leg pain to see if routine imaging alone is a…

This study looks at how forward head posture relates to trunk muscle strength and body awareness in people with cervical radiculopathy—a condition where a pinched nerve in the neck causes pain that travels down the arm. Researchers will measure head angle, trunk strength, and bal…