Timing of pain relief after back injection may predict Long-Term success

NCT ID NCT07367191

Not yet recruiting Knowledge-focused Sponsor: Marmara University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will follow 120 adults with sciatica from a herniated disc who receive a standard steroid injection. Researchers want to see if the speed and pattern of pain relief in the first few days and weeks can predict whether the treatment is still working at 3 and 6 months. Participants will rate their pain before the shot, one hour after, every 72 hours for 21 days, and then at 1, 3, and 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: betamethasone and bupivacaine (steroid and anesthetic injection)
What this could lead to: If successful, this could help doctors predict which patients will benefit most from epidural steroid injections for sciatica, improving treatment decisions.
What could go wrong: This is an observational study, not a test of a new treatment. It only looks at patterns in pain relief, so it won't prove whether the injection itself works better than other options.

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Conditions

The condition(s) this trial relates to.

Intervertebral Disc Displacement lumbar disk disease lumbar disk herniation, susceptibility to radiculopathy sciatica

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUMBAR DISC HERNIATION LUMBAR RADICULOPATHY RADICULAR LOW BACK PAIN SCIATICA

Contacts and locations

Locations

Marmara Üniversitesi Tıp Fakültesi, Istanbul, Maltepe 34854

Istanbul, Turkey (Türkiye)

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