SCIATICA
Clinical trials for SCIATICA explained in plain language.
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New online program aims to ease sciatica without drugs
Symptom relief Recruiting nowThis study tests a fully online program for people with sciatica or chronic low back pain with leg pain. The program combines mindfulness, gentle movement, and motivational coaching to help manage pain and improve daily function. Researchers will enroll 32 adults to see if the pr…
Matched conditions: SCIATICA
Phase: NA • Sponsor: National University of Natural Medicine • Aim: Symptom relief
Last updated May 12, 2026 13:43 UTC
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New shot for sciatica pain enters first human safety trial
Symptom relief Recruiting nowThis early-stage study tests a single injection of C-1101 in 24 adults with chronic sciatica (leg pain from a pinched nerve in the lower back). The main goal is to check safety and side effects compared to a saltwater placebo. Participants must have tried other treatments without…
Matched conditions: SCIATICA
Phase: PHASE1 • Sponsor: Consano Bio • Aim: Symptom relief
Last updated May 12, 2026 13:42 UTC
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Sham surgery showdown: is common back operation just a placebo?
Symptom relief Recruiting nowThis study compares real microdiscectomy surgery to a placebo (sham) surgery for people with sciatica from a herniated disc whose leg pain hasn't improved after 6 weeks of non-surgical care. 122 participants will be randomly assigned to either the real operation or a fake procedu…
Matched conditions: SCIATICA
Phase: NA • Sponsor: Helsinki University Central Hospital • Aim: Symptom relief
Last updated May 11, 2026 20:51 UTC