SCIATICA
Clinical trials for SCIATICA explained in plain language.
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Which nerve technique wins for sciatica? new trial aims to find out
Symptom relief Recruiting nowThis study compares two types of nerve-stretching exercises (tensioner and slider) for people with sciatica. Eighty participants with leg pain lasting 3 to 12 months will receive one of the techniques plus standard physical therapy. Researchers will measure pain, disability, and …
Matched conditions: SCIATICA
Phase: NA • Sponsor: Ibadat International University, Islamabad • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC
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Sham surgery showdown: is the knife worth it for sciatica?
Symptom relief Recruiting nowThis study tests whether a common back operation (microdiscectomy) actually relieves sciatica leg pain better than a pretend surgery. 122 adults with a herniated disc and persistent leg pain will be randomly assigned to get either the real operation or a sham procedure. Neither t…
Matched conditions: SCIATICA
Phase: NA • Sponsor: Helsinki University Central Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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Needle zap for sciatica: new study tests quick fix for leg pain
Symptom relief Recruiting nowThis study tests whether a single 30-minute session of electrical nerve stimulation (PENS) can quickly reduce sciatica pain and improve daily function. 88 adults with long-term sciatica will be randomly assigned to receive PENS, TENS (skin patches), dry needling, or a placebo. Re…
Matched conditions: SCIATICA
Phase: NA • Sponsor: Universidad Complutense de Madrid • Aim: Symptom relief
Last updated Jun 27, 2026 12:34 UTC
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New needle therapy could ease sciatica without drugs
Symptom relief Recruiting nowThis study tests whether a treatment called Percutaneous Electrical Nerve Stimulation (PENS), combined with exercise, can reduce pain and improve quality of life in people with long-term sciatica. 88 adults with chronic leg pain from sciatica will be randomly assigned to receive …
Matched conditions: SCIATICA
Phase: NA • Sponsor: Universidad Complutense de Madrid • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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New shot for sciatica pain enters first human safety study
Symptom relief Recruiting nowThis early-stage study tests a single injection of C-1101 into the spine area for people with long-term sciatica (leg pain from a pinched nerve). The main goal is to check if the treatment is safe and tolerable compared to a saltwater placebo. Only 24 adults with pain that hasn't…
Matched conditions: SCIATICA
Phase: PHASE1 • Sponsor: Consano Bio • Aim: Symptom relief
Last updated Jun 27, 2026 11:03 UTC
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Can mindfulness and movement ease sciatica? new study tests remote program
Symptom relief Recruiting nowThis study tests a remote program called Move-MORE for people with sciatica (nerve pain from the lower back into the leg). The program combines mindfulness, gentle movement, and motivational coaching to help manage pain and improve daily function. Researchers will enroll 32 adult…
Matched conditions: SCIATICA
Phase: NA • Sponsor: National University of Natural Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Scientists scan brains to unlock cannabis pain relief secrets
Knowledge-focused Recruiting nowThis study looks at how inhaled cannabis affects the brain in people with chronic low back pain. Researchers will use MRI scans to measure changes in brain blood flow and oxygen levels, and ask participants to rate their pain. The goal is to understand the brain mechanisms behind…
Matched conditions: SCIATICA
Phase: EARLY_PHASE1 • Sponsor: University of California, San Diego • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC