New shot for sciatica pain enters first human safety study
NCT ID NCT07264270
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study tests a single injection of C-1101 into the spine area for people with long-term sciatica (leg pain from a pinched nerve). The main goal is to check if the treatment is safe and tolerable compared to a saltwater placebo. Only 24 adults with pain that hasn't improved with standard care will take part.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Consano Bio Research Site
RECRUITINGBroadmeadow, New South Wales, Australia
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Consano Bio Research Site
RECRUITINGWahroonga, New South Wales, Australia
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Consano Bio Research Site
RECRUITINGMelbourne, Victoria, Australia
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can one injection beat back pain? a trial aims to find out
- Can a simple tape boost sciatica recovery and balance?
- Nerve flossing for athletes: a simple technique that could keep hamstrings strong?
- Shockwave or ultrasound? trial aims to settle which therapy eases sciatica pain and improves sleep
- Simple leg test could rival injections for diagnosing nerve pain
- Hidden clues on CT: three signs that may pinpoint the nerve behind sciatica pain