Radiculopathy

This study compares a new implant with special nanoLOCK technology to standard implants used in neck fusion surgery. The goal is to see if the new implant helps bones heal better and causes fewer swallowing problems. About 200 adults with neck pain or nerve issues will be randoml…

This study tests a new artificial disc implant (PerQdisc) placed during surgery for a herniated disc. The goal is to see if it is safe and helps reduce back and leg pain. About 50 adults with a single herniated disc in the lower back will take part. The implant is meant to replac…

This study is testing a metal plate (the NuVasive ACP system) used during neck spine surgery to treat conditions like disc disease, stenosis, or fractures. About 75 adults will receive the plate and be followed for up to 24 months to see how safe it is and how well it helps with …

This observational study is testing whether integrative Korean medicine—combining herbal medicine and Chuna manual therapy—can safely reduce pain and improve quality of life in 120 adults with cervical disc herniation and radiculopathy. Participants receive treatment at four Kore…

This study tests a device called PCSS used alongside standard neck fusion surgery to treat degenerative disc disease in the neck. About 236 adults aged 18-80 who need surgery on three neck levels will be enrolled. The goal is to see if the device helps bones fuse better and safel…

This study compares two physical therapy methods for people with lumbar radiculopathy (a pinched nerve in the lower back causing leg pain). Thirty adults aged 25 to 50 with moderate disability will receive either spinal mobilization with leg movement or mechanical traction for fo…

This study compares two manual traction techniques—Mulligan belt traction and fisted traction—for people with lower cervical radiculopathy (pinched nerve in the neck causing pain down the arm). 44 adults aged 25-60 with moderate pain will be assigned to one of the two methods. Re…

This study tests two physical therapy techniques for people with lumbar radiculopathy (sciatica). One group does a standard muscle stretching method, while the other adds a nerve-gliding exercise. Researchers will measure pain, flexibility, and daily function in 22 adults aged 30…

This study looks at whether a non-surgical treatment called spinal decompression can help people with chronic low back pain. About 42 adults with back pain from disc problems or sciatica will receive the treatment over 12 weeks. Researchers will use MRI scans and movement tests t…

This study looks at two ways to numb people for lower back surgery: general anesthesia (being fully asleep) plus a nerve block, or spinal anesthesia (numbing only the lower body) plus a nerve block. The goal is to see which approach helps patients recover better and feel less pai…

This study compares two common procedures for chronic back pain caused by a slipped disc or narrowed spine: a steroid injection and a nerve-targeting radiofrequency treatment. Researchers will track pain levels in 200 adults right after the procedure and three weeks later. The go…

This study tests whether Qutenza 8% capsaicin skin patches can safely and effectively treat nerve-related lower back pain and leg pain (sciatica). Fifty adults with symptoms lasting over three months will receive up to four patches per visit over five visits in a year. The main g…

This study tests whether repeated magnetic pulses (rTMS) aimed at the brain's motor area can safely reduce chronic nerve pain that hasn't responded to other treatments. About 32 adults with conditions like post-stroke pain, trigeminal neuralgia, or spinal cord injury will receive…

This study looked back at medical records of 330 adults with cervical radiculopathy (pinched nerve in the neck causing pain down the arm). It compared two types of injections: one guided by ultrasound and one guided by X-ray. The goal was to see which method reduces pain more, sp…

This study tests if a wrap made from donated birth tissue (amniotic membrane) can reduce swelling after a two-level neck fusion surgery. About 50 adults with neck spine problems will take part. The main goal is to see if the wrap lessens soft tissue swelling one month after surge…

This study watches 24 adults who are getting standard neck fusion surgery with a special device called the BEE HA cage. The goal is to see how well the cage helps with pain and function over time. No new treatment is tested—just careful tracking of normal surgery results.

This study reviews medical records of 40 adults with chronic leg pain from back problems who had a procedure called caudal epidural adhesiolysis. The procedure uses a thin tube to break up scar tissue around spinal nerves. Researchers want to find out which patient traits or proc…

This study looks at how headaches work by using capsaicin (the spicy part of chili peppers) and ice water to trigger mild, temporary pain in people with and without headache disorders. Researchers measure changes in pain signals and tear production to better understand conditions…

This study follows 150 adults undergoing back-of-the-neck and upper spine surgery with metal screws and rods (posterior fixation) for injuries, tumors, or worn-out discs. Researchers track complications, X-ray results, and patient-reported pain over time. The goal is to better un…