Capsaicin patch trial targets nerve pain in lower back and legs
NCT ID NCT06540456
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether Qutenza 8% capsaicin skin patches can safely and effectively treat nerve-related lower back pain and leg pain (sciatica). Fifty adults with symptoms lasting over three months will receive up to four patches per visit over five visits in a year. The main goal is to check for side effects and measure changes in pain and quality of life using surveys.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Qutenza 8% capsaicin topical system (skin patch)
What this could lead to
If it works, this could offer a new topical treatment option for people with nerve-related lower back and leg pain, potentially reducing pain and improving quality of life.
What could go wrong
This is a small, early pilot study with only 50 participants, so results may not apply to everyone. Capsaicin can cause skin irritation or burning at the application site.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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MUSC Health Nexton Medical Park
Summerville, South Carolina, 29483, United States