Scientists use chili peppers and ice water to unlock headache secrets
NCT ID NCT03511846
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how headaches work by using capsaicin (the spicy part of chili peppers) and ice water to trigger mild, temporary pain in people with and without headache disorders. Researchers measure changes in pain signals and tear production to better understand conditions like migraine and cluster headache. The goal is to find better ways to diagnose and treat these painful conditions.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Locations
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The University of Texas Health Science Center at Houston
Houston, Texas, 77030, United States