Scientists use chili peppers and brain freeze to unlock headache secrets
NCT ID NCT03511846
First seen Feb 19, 2026 · Last updated May 16, 2026 · Updated 9 times
Summary
This study looks at how headache disorders like migraine and cluster headaches affect pain signals in the body. Researchers will use capsaicin (from chili peppers) and ice water to trigger mild pain or tearing, then measure changes in molecules and tear production. The goal is to better understand these conditions, not to treat them. About 371 adults with or without headaches will take part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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The University of Texas Health Science Center at Houston
Houston, Texas, 77030, United States
Conditions
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