Paroxysmal Hemicrania
MONDO:0015529Paroxysmal hemicrania (PH) is a primary headache disorder characterized by multiple attacks of unilateral pain that occur in association with cranial autonomic symptoms. The hallmarks of this syndrome are the relative shortness of the attacks and the complete response to indomethacin therapy.
12 clinical trials for this condition and its sub-types.
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Ear needle zaps headaches? new study uses heat cameras to find out
Symptom relief Recruiting nowThis study tests whether inserting a tiny needle into the ear and applying a mild electrical current (called percutaneous needle electrolysis) can help people with frequent headaches. Researchers will use an infrared camera to measure changes in facial skin temperature, since peo…
Phase: NA • Sponsor: University of Alcala • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Nose injection could ease debilitating face pain for days
Symptom relief Recruiting nowThis study tests whether injecting a long-lasting numbing medication (Exparel) into the side of the nose can reduce severe face and headache pain. About 15 adults with conditions like migraine or cluster headache will receive either the drug or a placebo, then switch groups. The …
Phase: PHASE2 • Sponsor: Stanford University • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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The eyes as a window to the brain: can a simple scan monitor MS, Alzheimer's, and Parkinson's?
Knowledge-focused Recruiting nowThis study is testing whether a non-invasive eye scan called optical coherence tomography (OCT) can help track neurological diseases like multiple sclerosis, Alzheimer's, Parkinson's, and migraine. Over two years, researchers will measure the thickness of retinal layers in 840 pa…
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Jul 24, 2026 00:00 UTC
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Massive study aims to unlock secrets of debilitating head pain
Knowledge-focused Recruiting nowThis study is gathering information from 1,500 people with cluster headache or trigeminal neuralgia to learn more about these painful conditions. Researchers will collect surveys, genetic samples, and other health data. The goal is to better understand what causes these headaches…
Sponsor: The University of Texas Health Science Center, Houston • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC