Paroxysmal Hemicrania
MONDO:0015529Paroxysmal hemicrania (PH) is a primary headache disorder characterized by multiple attacks of unilateral pain that occur in association with cranial autonomic symptoms. The hallmarks of this syndrome are the relative shortness of the attacks and the complete response to indomethacin therapy.
12 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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New hope for migraine sufferers? Needle-Freezing technique targets pain hub
Symptom relief CompletedThis study tested a minimally invasive procedure called pulsed radiofrequency on a nerve bundle in the face (the sphenopalatine ganglion) to see if it could reduce pain in 55 people with chronic headaches or facial pain who hadn't gotten relief from medication. The procedure uses…
Phase: NA • Sponsor: Ankara City Hospital Bilkent • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Tailored therapy shows promise for teens with headaches
Symptom relief CompletedThis study tested a personalized psychological intervention for 5 adolescents aged 12-18 with recurrent headaches. Researchers used smartphone surveys to track each teen's unique headache triggers and coping patterns, then delivered 4-5 weekly online therapy sessions based on tha…
Phase: NA • Sponsor: Royal Holloway University • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Hands-On therapy may rewire headache brains, pilot study shows
Knowledge-focused CompletedThis study looked at how osteopathic manual therapy (OMT) changes the brain in people with migraines, tension, or cluster headaches. Researchers used MRI scans to see if OMT affects brain structure and activity. The goal was to understand how OMT reduces pain and disability, not …
Phase: NA • Sponsor: Edward Via Virginia College of Osteopathic Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Blood protein may help ER spot serious headaches
Knowledge-focused CompletedThis study looked at whether measuring a protein called S100B in the blood can help emergency doctors tell the difference between primary headaches (like migraines) and secondary headaches (caused by something serious like a bleed or infection). Researchers enrolled 81 adults wit…
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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Headaches linked to poor sleep and mental health in new study
Knowledge-focused CompletedThis study looked at how headaches impact sleep, pain sensitivity, and emotional well-being in 132 adults aged 18-65. Researchers measured sleep quality, central sensitization (a heightened pain state), and levels of depression, anxiety, and stress using standard questionnaires. …
Sponsor: Nagihan Acet • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC