Hip fracture

This study is testing a new hip implant called the OR3O Dual Mobility System in 177 people who need hip replacement surgery. The goal is to see if the implant is safe and lasts longer without needing another surgery. Researchers will follow participants for up to 10 years to chec…

This study tests a special titanium implant, called iFuse-3D, along with screws to treat pelvic fractures in people aged 60 and older. The goal is to see if this surgery helps patients get back to their usual walking ability by the time they leave the hospital. Fifty participants…

This study looks at how well the Insignia Hip Stem works and how safe it is for people needing a total hip replacement. It includes 313 adults with conditions like hip arthritis or fractures. Researchers will check implant survival and hip function for up to 10 years after surger…

This pilot study tests whether metformin, a common diabetes drug, can help older adults recover muscle and function after a hip fracture. Sixty people aged 60 and older will take either metformin or a placebo daily for 4 months after surgery. The main goal is to see if the study …

This study is checking how well a new hip replacement part (the HYPE stem) works and lasts over 10 years. About 180 people with hip disease from arthritis or injury will get the implant. Doctors will use X-rays and surveys to see if the implant stays firmly in place and helps red…

This study planned to test a new hip replacement device (the HYPE stem) in people with hip arthritis or other hip damage. The goal was to see how well the device works and if it is safe. However, the study was withdrawn before any participants were enrolled, so no results are ava…

This study looks at how well a metal nail system (T2 Alpha Femur Antegrade GT/PF Nail) works for treating broken thigh bones (femur fractures). About 66 adults will receive the nail, and their leg function will be checked after 12 months. The goal is to see if this nail helps peo…

This study was designed to see if giving calcium right away to trauma patients who need large blood transfusions could help their blood clot better, reduce the need for more transfusions, and improve survival. The trial was withdrawn before enrolling any participants, so no resul…

This study follows 52 people who already received a Vivacit-E hip liner during total hip replacement. Researchers will track how long the implant lasts and any problems over 10 years. The goal is to confirm the liner is safe and helps reduce pain and improve movement for conditio…

This study followed 413 people with hip arthritis who received a new type of hip replacement called the OXINIUM DH system. The goal was to see how well the implant worked and how safe it was over 10 years. Researchers checked pain, movement, and whether the implant stayed in plac…

This study is checking the long-term safety and performance of two hip implant devices (RingLoc Bipolar Acetabular Cup and Endo II Femoral Head) used in hip replacement surgery. Researchers will follow 116 patients who had their surgery at least eight years ago, tracking complica…

This study compares two types of antibiotic-loaded bone cement used during hip fracture surgery to see which better prevents joint infections. About 7000 patients aged 60 and older with displaced femoral neck fractures will be included. Hospitals are randomly assigned to use eith…

This study looks at the safety and performance of a cemented hip stem (TrendHip®) in 119 people who had hip replacement surgery. It tracks pain, function, and quality of life for up to 5 years after surgery. The goal is to confirm the device works well in everyday use.

This study follows 102 people who received the aneXys hip replacement cup to see how safe and effective it is over 2 years. Researchers measure if the cup moves and track pain and function using standard scores. The goal is to confirm the device works well in everyday use.

This study tests a new heating device called Therm'Up to manage hypothermia in trauma patients. Hypothermia, when body temperature drops below 35°C, can worsen injuries and increase death risk. The trial will enroll 100 adults at risk of hypothermia due to trauma, cold exposure, …

This study was designed to test a new metal implant called the Artemis Proximal Femoral Nail for fixing a common type of hip fracture. The plan was to compare results from patients who received this implant to similar patients from the past who received other implants. However, t…

This study tracks 100 adults who need a hip replacement to see how well the Avenir cemented hip stem works and holds up over time. Participants have conditions like arthritis, hip fractures, or hip damage from past surgeries. The main goal is to measure how long the implant lasts…

This study looks at how well Biomet Cannulated Bone Screws work for fixing broken bones, fusing joints, or correcting bone cuts. It includes 51 adults who already had or will have surgery with these screws. Researchers track complications, revisions, and patient feedback to confi…

This study is following 202 people who received a special hip liner during hip replacement surgery. The goal is to see how long the liner lasts and whether it causes any problems over time. Participants are adults aged 18 to 80 with conditions like arthritis or hip fractures. The…

This study follows 100 people who need a hip replacement to see how long the MiniMAX hip stem lasts and how well it works. Participants receive the stem during surgery and are checked for implant survival and hip function using the Harris Hip Score. The goal is to confirm the ste…

This study tests a new ultrasound device that measures bone properties in the lower leg to predict fracture risk in adults over 55. It aims to see if it works as well as or better than standard DXA scans, without using radiation. Researchers will follow 1,600 participants for thr…

This study tests a handheld device called the Osteoprobe that measures bone strength by pressing on the shinbone. Researchers want to see if it can identify women at risk for hip and wrist fractures better than standard bone density scans. About 190 women with recent fractures an…

This study tests a program designed to prevent opioid misuse in people hospitalized for a traumatic injury. Participants complete brief questionnaires about pain and opioid use risk, and receive enhanced care coordination based on their responses. The goal is to see if this adapt…

This study looks at whether a fall prevention discharge class can reduce repeat fall-related ER visits in adults aged 60 and older. Researchers will compare those who attended the class to those who did not. The goal is to see if this simple education step can help prevent future…

This study compares two types of nerve blocks (PENG and FICB) to see which provides better pain relief for people with hip fractures in the emergency department. About 50 adults with a broken hip will receive one of the two blocks, and researchers will measure their pain scores a…

This study compares two ways to manage pain before spinal anesthesia for hip fracture surgery: a fascia iliaca block (a numbing injection near the hip) versus intravenous nalbuphine (a painkiller given through a vein). Researchers will measure pain scores and how well patients ca…

This study tests a communication tool called Best Case/Worst Case-ICU for older adults (50+) with serious injuries in the ICU. The tool helps doctors, patients, and families discuss possible outcomes and treatment options using simple graphics. Researchers will measure if it impr…

This trial tests whether a Pain and Coordination Plan (PAC-plan) can reduce opioid use and improve quality of life in adults who have had surgery after an accidental injury. Participants receive the plan at hospital discharge, which includes an opioid management plan, a follow-up…

This study tests a new method of spinal anesthesia for elderly patients (65+) having hip fracture surgery. The goal is to see if using a mix of two types of anesthetic given in small doses can reduce dangerous drops in blood pressure compared to standard methods. The study involv…

This study tests a brief stepped care program for adults hospitalized after a traumatic injury who show signs of PTSD. The program starts in the hospital and aims to reduce PTSD symptoms and the number of emergency room visits over time. About 424 participants are involved, and t…

This study compares two surgical techniques for repairing a broken hip (femoral neck fracture) in adults over 50. One is the standard direct lateral approach, and the other is a newer muscle-sparing method called SPAIRE. Researchers want to see which approach leads to better hip …

This early-phase trial compares two drugs—dexamethasone and dexmedetomidine—added to standard spinal anesthesia for pelvic fracture surgery. Sixty adults will be split into two groups to see which combination provides longer pain relief and better recovery. The goal is to find a …

This pilot study tests whether adding blood flow restriction therapy to standard physical therapy helps elderly patients (65 and older) recover muscle strength and size after hip fracture surgery. Twenty participants will have their thigh and leg measurements, muscle strength, pa…

This study tests whether a wearable robot suit can help people aged 65 and older recover leg function after hip fracture surgery. Participants will either do standard rehab or use the robot suit during therapy. The goal is to see if the robot improves walking, balance, and pain b…

This study looks at two different nerve block techniques used alongside low-dose spinal anesthesia for hip fracture surgery in elderly patients. The goal is to see which method better prevents severe drops in blood pressure during surgery and improves pain control afterward. Abou…

This study looks at two different nerve-block methods to control pain after hip surgery. One group gets a standard block that numbs the hip joint, while the other gets an extra block for the thigh skin. The goal is to see which method reduces pain, lowers the need for pain medici…

This study compares two types of nerve blocks—pericapsular nerve block and anterior quadratus lumborum block—for reducing pain during spinal anesthesia positioning and after surgery in people with hip fractures. Researchers will enroll 64 adults aged 30-85 scheduled for hip fract…

This study looks at whether applying heat and giving abdominal massage soon after hip fracture surgery can improve bowel function and mental well-being. About 75 adults who had hip surgery and haven't had a bowel movement yet will receive these treatments twice a day for three da…

This study compares two types of nerve blocks (PENG and FIC) to see which provides better pain relief for adults with hip fractures in the emergency department. About 80 participants will receive one of the blocks and report their pain levels. The goal is to find a safer, opioid-…

This study aimed to see if giving a nerve block before and after hip fracture surgery could reduce pain, confusion, and hospital stays in patients 65 and older. The trial was withdrawn before any participants were enrolled, so no conclusions can be drawn.

This study looks at whether adding acupuncture to usual care (painkillers and physical therapy) can improve pain and mobility in people recovering from hip fracture surgery. About 90 adults aged 40–99 will be randomly assigned to receive either standard care alone or standard car…

This study compares two types of nerve blocks—SFIB and PENG—to see which one controls pain better after hip replacement surgery. Sixty patients will be randomly assigned to receive one of the blocks. The main goal is to measure how much morphine they need in the first 24 hours af…

This study looks at 200 older adults (65+) who had hip fracture surgery. Researchers compared two common rating systems—the ASA score and the Clinical Frailty Scale—to see which better predicts whether a patient will need intensive care after surgery. The goal is to help doctors …

This study looks back at medical records of 233 older adults (65+) who had hip fracture surgery. Researchers want to see if certain blood test results, taken before and after surgery, can help predict who is at higher risk of dying within 30 days or needing a longer stay in the i…

This study looks at how serious combat injuries affect the long-term health of U.S. military members. Researchers will measure heart function, sleep quality, and stress-related body signals in 200 injured service members. The goal is to understand links between injury severity, s…

This study looks at over 110,000 people who had hip replacement surgery to see if a longer or shorter hip stem works better. It compares death rates, how often the hip implant needs to be replaced, and patient-reported pain and function. The goal is to find out which stem length …

This study compares two surgical techniques (posterior SPAIRE and anterior approach) for treating broken hips in people aged 70–90. Researchers will measure recovery, muscle damage, and bone density changes in 210 participants. The goal is to see if one approach leads to better o…

This study is observing 60 people who received a special hip replacement cup (Plasmafit Revision Structan) during routine surgery. Researchers are checking how well the cup works and how long it lasts by tracking hip function and any need for repeat surgery. No new treatment is b…

This study aimed to compare three medicines (propofol, etomidate, and ketamine) given to adult trauma patients to help them breathe with a breathing tube. The goal was to see which drug leads to the best outcomes, like survival and fewer side effects. However, the study was withd…

This study looks at whether a computer model can predict heart injury after major orthopedic surgery in patients 65 and older. Researchers will combine blood tests, frailty scores, and other health data to build a machine learning tool. The goal is to help doctors spot high-risk …

This study looks back at 300 patients who had a hip replacement after a cancer-weakened bone broke. Researchers want to see how well patients walk, their pain levels, and how long they live compared to patients from decades ago. The goal is to find what helps people walk again af…

This pilot study at Johns Hopkins will enroll 24 older adults having hip fracture surgery with bone cement. It compares general anesthesia to epidural (neuraxial) anesthesia to see which one lowers the risk of bone cement implantation syndrome—a serious complication that can caus…

This study follows 248 adults receiving a CoreHip hip replacement to see how their hip function, pain, and leg length change over time. Participants are treated as part of routine care, and no extra tests or treatments are given. The goal is to collect real-world data on the impl…

This study looks at how the body's natural response to severe injury or major surgery can sometimes go wrong, leading to complications. Researchers will collect blood samples from 320 trauma patients and elective surgery patients to measure markers of inflammation and blood clott…

This observational registry will follow 5,000 adults with various wounds—like diabetic foot ulcers, burns, or surgical wounds—to see how different treatments (e.g., hydrocolloid, foam, silver dressings) perform in everyday medical settings. Researchers will measure wound healing,…

This study follows about 1500 adults with hip, shin, ankle, upper arm, or wrist fractures for up to one year. Researchers collect information on healing, patient-reported symptoms, and activity patterns using questionnaires and wearable sensors. The goal is to understand recovery…

This study looks at two common surgeries for a certain type of hip fracture in people aged 60 and older: hip replacement or using screws/pins to hold the bone together. The main goal is to see if a larger study is possible by checking how many people join, how well the treatments…

This study is tracking over 600 people who received the GORE VIABAHN stent-graft as part of their normal medical care for conditions like peripheral artery disease or aneurysms. Researchers are monitoring how often serious device-related problems occur. The goal is to see how saf…

This study asks over 2,300 people with various joint conditions (like arthritis, fractures, and hip problems) to fill out surveys about their treatment preferences. Researchers want to learn how factors like pain, recovery time, cost, and surgery versus non-surgery affect patient…

This study follows 432 adults who were in the ICU after a traumatic injury or burn. Researchers want to see if and why patients develop long-term problems with memory, thinking, and daily function. By tracking cognitive skills and inflammation over time, they hope to uncover link…

This study compares two surgical methods for fixing a broken hip (femoral neck fracture) using a dynamic hip screw. In one method, the surgeon makes a larger cut to see the bone directly (open reduction); in the other, the bone is aligned without a large cut (closed reduction). T…

This study will track 100 people with traumatic hand and wrist injuries at Sohag University Hospital in Egypt from October 2025 to April 2026. Researchers want to learn how these injuries happen and what the outcomes are. It is an observational study, meaning no new treatment is …

This study checks how well 10 existing prediction models can estimate the chance of dying within 30 days after a hip fracture. Researchers will look at data from 3500 patients in the Netherlands, using about 35 health factors. The goal is to find models that are accurate and usef…