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Hip replacement liners put to the test in global study

NCT ID NCT04754087

Ongoing Disease control Sponsor: Zimmer Biomet Source: ClinicalTrials.gov ↗

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study follows 300 people who receive a hip replacement using either the Vivacit-E or Longevity liner, both made of a special plastic designed to last longer. The goal is to see how well these liners hold up over time, measuring how many are still in place without needing replacement and tracking any side effects. Participants include adults with hip conditions like osteoarthritis, rheumatoid arthritis, or hip fractures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
two types of hip replacement liners: Vivacit-E and Longevity highly crosslinked polyethylene (HXLPE)
What this could lead to
If successful, this study could confirm that these liners are safe and effective for long-term use in hip replacements, potentially reducing the need for revision surgery.
What could go wrong
This is an observational follow-up study, not a randomized controlled trial, so results may be influenced by patient selection. The liners may still wear out or cause complications over time.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

avascular necrosis avascular necrosis of femoral head, primary, 1 familial avascular necrosis of femoral head femoral neck fracture hip fracture osteoarthritis susceptibility 5 osteoarthritis, hip rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AVASCULAR NECROSIS OF HIP DEGENERATIVE JOINT DISEASE OF HIP FRACTURE OF HIP FRACTURES, HIP OSTEOARTHRITIS OF HIP OSTEOARTHRITIS, HIP RHEUMATOID ARTHRITIS OF HIP TOTAL HIP ARTHROPLASTY

Contacts and locations

Locations

  • Colorado Joint Replacement

    Denver, Colorado, 80210, United States

  • Copenhagen University Hospital Hvidovre

    Hvidovre, 2650, Denmark

  • Duke University Medical Center

    Durham, North Carolina, 27703, United States

  • OCON Hengelo

    Hengelo, Netherlands

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • Skane University Hospital

    Lund, 221 85, Sweden

  • Slocum Center for Orthopedics & Sports Medicine

    Eugene, Oregon, 97401, United States

  • South Bend Orthopaedics

    South Bend, Indiana, 46635, United States

  • The Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust Royal Bournemouth Hospital

    Bournemouth, UK, BH7 7DW, United Kingdom

  • University of Utah Health

    Salt Lake City, Utah, 84112, United States

  • Zuyderland Hospital

    Geleen, 6162 BG, Netherlands

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