Osteoarthritis susceptibility 5

This study is testing a new hip replacement system called the HIT Reverse Hip Replacement System. It is for people aged 50 to 75 who need a total hip replacement due to arthritis, joint damage, or other conditions. The goal is to see if the new system is as safe and effective as …

This study tests whether daily cannabis extracts (CBD or THC) can reduce pain interference in people with hip or knee osteoarthritis. One hundred adults aged 40-80 will take either CBD, THC, or a placebo capsule daily for 8 weeks and track their symptoms remotely. The goal is to …

This study tests whether a pharmacist-led program can help patients reduce their opioid use by about half in the weeks before knee or hip replacement surgery. 45 adults on stable, moderate-dose opioids will work with a pharmacist to create a taper plan and get weekly check-ins. T…

This study is testing whether low-impact group exercise classes can help reduce pain in people with knee, hip, or ankle osteoarthritis. Participants attend one-hour group sessions three times a week for six months, led by a physical therapist or trainer. The study also includes s…

This study aims to better understand and treat people with certain inherited metabolic or genetic disorders. Researchers will use standard medical tests like blood work and imaging to diagnose and care for participants, who may also join other related studies. The goal is to expa…

This study is recruiting 100 people who need hip replacement surgery after a fragility fracture (a break from a minor fall) and comparing them to patients having hip replacement for arthritis. Researchers will use a simple questionnaire (SARC-F) and analyze bone and muscle tissue…

This study is testing a new online platform called Nest for young adults aged 18-39 who have had genetic testing for cancer risk. The platform gives both patients and their doctors access to updated information about genetic findings. Researchers want to see if the tool is easy t…

This study from St. Jude Children's Research Hospital looks at how parents and children (ages 10-24) talk about the child's genetic risk for cancer. The goal is to understand what helps or hinders these conversations, so doctors can create better education programs. The study wil…

This study compares two ways of closing the wound after hip or knee replacement surgery: barbed sutures (a newer type) versus conventional sutures. About 90 adults having hip or knee replacement will be randomly assigned to one method. Researchers will track wound healing, compli…

This study compares two ways to provide pre-test genetic counseling to people at high risk for hereditary cancers: a chatbot (Genetic Information Assistant) versus a live telegenetics session with a genetic counselor. About 96 participants will be randomly assigned to one method,…