Which anesthesia is safer for hip fracture surgery? new study aims to find out
NCT ID NCT06952257
First seen Jun 25, 2026 · Last updated Jul 22, 2026 · Updated 3 times
Summary
This pilot study at Johns Hopkins will enroll 24 older adults having hip fracture surgery with bone cement. It compares general anesthesia to epidural (neuraxial) anesthesia to see which one lowers the risk of bone cement implantation syndrome—a serious complication that can cause breathing problems, low blood pressure, or even cardiac arrest. The study also measures histamine and complement levels to understand why the syndrome happens.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- General anesthesia (intravenous) and neuraxial analgesia (epidural)
- What this could lead to
- If it works, this could point toward safer anesthesia choices to reduce serious complications during hip fracture surgery.
- What could go wrong
- This is a very small pilot study with only 24 participants, so results may not apply broadly. It is early-stage research, not a treatment trial.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Dept of Orthopadic Surgery, Johns Hopkins Hospital, JHOC 5221, 601 N. Caroline St.
Baltimore, Maryland, 21287, United States