University Hospital, Strasbourg, France

This study looks at whether the antibiotic clindamycin works as well as other drugs for treating Streptococcus infections in artificial joints. Researchers will compare success rates in 260 adults who had surgery for this infection. The goal is to see if clindamycin can be a good…

This study looks at how well a non-surgical endoscopic treatment works for people who have bile duct injuries from gallbladder or liver surgery. Researchers will track 220 adults to see how many get better after the procedure and stay better for at least 3 months. The goal is to …

This study tests if freezing desmoid tumors (cryoablation) works better than standard medication for people whose tumors grew after initial monitoring. About 150 participants aged 13+ with progressive desmoid tumors will be randomly assigned to cryoablation or medical therapy. Th…

This study looks at whether reducing immunosuppressive medications (along with giving a steroid) helps kidney transplant patients recover faster when they are in the intensive care unit for septic shock or severe breathing failure. About 212 adults whose transplant was at least 3…

This study tests whether eating small, increasing amounts of raw apple can reduce mouth allergy symptoms in people who are allergic to both birch pollen and apples. 110 participants will eat either real apple or a placebo over 9 months. The goal is to see if they can tolerate a l…

This study looks at when to give a blood thinner (heparin) during a heart procedure done through the wrist. Giving it before inserting the tube might lower the risk of blocking the wrist artery, which can happen in up to 30% of patients. The trial will involve 550 adults and chec…

This study looks at a new way to fix a common elbow fracture in children using anchors with sutures instead of screws or pins. The goal is to reduce problems like hardware irritation and the need for a second surgery to remove implants. Nine children under 15 with displaced fract…

This study looks at whether replacing an infected hip or knee joint in a single surgery works as well as the usual two-step approach for a rare Candida fungal infection. Researchers will check if the infection clears up after one surgery combined with antifungal medicine. The stu…

This study looks at whether using one antibiotic or a combination of two antibiotics works better for a serious bloodstream infection caused by Enterococcus faecalis. The infection can be deadly, with a 15-25% death rate. Researchers will track 700 adults to see which approach lo…

This study is testing whether specially trained dogs can detect bladder cancer by smelling urine samples. Researchers will collect urine from 340 adults scheduled for bladder surgery and see how often the dogs correctly identify cancer. If it works, this could lead to a simple, n…

This pilot study is testing a new MRI technique called brainQuant to see if it can find early signs of brain damage in professional soccer players. Repeated headers may cause tiny brain injuries that lead to chronic traumatic encephalopathy (CTE). The study will scan 80 male socc…

This study reviews medical records of 500 adults who came to the emergency room with possible pulmonary embolism (a blood clot in the lungs). Researchers want to see if using two checklists, called PERC and YEARS, could have safely avoided CT scans in many patients. The goal is t…

This study tests whether a special CT scan (dual-energy CT) can be as good as MRI for staging mouth and throat cancers. If it works, patients might avoid an extra MRI, get treatment faster, and free up MRI machines for others. About 30 adults with these cancers will be enrolled t…

This study compares a new test called Cryocheck HexLA to current methods for detecting lupus anticoagulant, a substance that can increase blood clot risk. Researchers will analyze blood samples from 200 adults to see if the new test is more accurate and less affected by blood-thi…

This study looks at whether a simple decision-making flowchart can help general practitioners better diagnose and refer patients with vertigo. Researchers will compare the tool's diagnosis with that of an ear, nose, and throat specialist. The goal is to improve patient care and r…

About 30% of people who have surgery for a herniated disc still suffer from nerve pain afterward. This study tests whether applying a gel made from the patient's own blood (platelet-rich fibrin) around the nerve during surgery can prevent that chronic pain. The trial will enroll …

This study looks at whether giving pregnant women free organic vegetables and healthy-eating workshops can reduce their exposure to pesticides. Researchers will compare urine pesticide levels in women who get the veggies versus those who eat as usual. The goal is to see if this s…

This study tests whether a personalized facial rehabilitation program can help people with systemic sclerosis who have facial tightness and mouth problems. About 60 adults with this rare autoimmune disease will either receive the rehab program or standard care. The goal is to see…

This study tests whether dialectical behavior therapy (DBT), a type of talk therapy, can help people with acquired brain injury manage emotional distress and challenging behaviors. 77 participants will receive standard care for 5 months, then DBT for 5 months, then follow-up. Res…

This study tests whether hearing their mother's voice can reduce pain in very premature babies during a common blood draw procedure (venipuncture). About 48 babies born before 32 weeks will be studied, comparing standard pain relief with added maternal voice contact. The goal is …

This study tests whether giving parents an easy-to-understand information sheet after their child's first simple febrile seizure reduces repeat emergency visits and eases anxiety. About 100 parents of children aged 9 months to 5 years will receive the sheet during their first ER …

This study looks at two ways to treat multiple sclerosis (MS) when it first appears after age 50. One approach starts with a moderate-strength drug and only switches to a stronger one if needed. The other starts with a strong drug right away. Researchers will compare how often re…

This study interviews staff and caregivers at two medicalized residential facilities in Alsace, France, to understand what helps or hinders creating care plans for vulnerable patients receiving palliative care. Researchers will analyze conversations to identify key factors like s…

This study looks back at 100 cases of human babesiosis, a rare tick-borne disease, diagnosed in France between 2000 and 2024. Researchers want to describe who gets it, what symptoms they have, and how they are treated. The goal is to improve recognition and care, especially for v…

This study looks at how doctors currently screen and treat obstructive sleep apnea in children with Down syndrome at one hospital. By reviewing past records of 30 children, researchers hope to create a standard care plan that can be used across France. The goal is to improve brea…

This study looks at how sleep affects memory in children with certain types of epilepsy. Researchers will test memory before and after sleep in 95 children, comparing those with mild epilepsy, severe epilepsy, and no epilepsy. The goal is to see if epileptic brain activity during…

This study looks at how doctors at Strasbourg University Hospital manage severe stomach or intestinal bleeding in patients taking blood thinners (DOACs). Researchers will review medical records of 250 adults to see how often a drug called prothrombin complex concentrate is used t…

This study tests whether spinning blood samples at very high speed can remove fat particles that interfere with a key test for blood thinners. Researchers will add fat to routine blood samples from 150 adults on anti-Xa medications and see if the spinning method clears the fat wi…

This study at Strasbourg University Hospital surveys 20 teenage girls (ages 11-18) with female hypogonadism and their parents to assess their knowledge of hormone replacement therapy. The goal is to identify gaps in understanding so that better educational workshops can be design…

This study looks at cases of severe Lyme disease (disseminated borreliosis) in patients who have received anti-CD20 therapy, a type of immune-suppressing treatment. Researchers want to describe the symptoms, severity, and progression of the infection in these patients. The study …

This study looks at using liver elastography, a non-invasive ultrasound-like technique, to measure liver fibrosis in children with type III glycogen storage disease (GSDIII). The goal is to see if this method can replace painful liver biopsies for monitoring disease progression. …

This study looks at whether a rectal swab can predict which intensive care patients will get infections from drug-resistant bacteria. Researchers will test 1,000 adults in French ICUs to see if a negative swab reliably means no infection. The goal is to help doctors avoid unneces…

This study aims to improve how doctors choose antibiotics for patients who say they are allergic to penicillin-like drugs (beta-lactams) before orthopedic surgery. Many people think they are allergic, but only a small fraction truly are. Researchers will use a simple questionnair…

This study follows 36 people with type 1 diabetes who have received a pancreatic islet transplant. Researchers will use continuous glucose monitors to see if a measure called 'Time in Tight Range' can detect early loss of graft function. The goal is to find a simple way to spot p…

This study compares two versions of the Nuss surgery for pectus excavatum (sunken chest) in teenagers aged 11 to 18. Researchers will look at 80 patients' records to see which technique leads to shorter surgery, less pain, and better cosmetic results. The goal is to help surgeons…

This study looks at whether a tool called the HScore can accurately diagnose hemophagocytic lymphohistiocytosis (HLH) in intensive care patients with liver failure or cirrhosis. Researchers will review medical records of 100 adults admitted to one hospital over ten years who had …

This study looks at mouth and tooth problems in people with rare diseases. Researchers will collect information from up to 1,300 patients to better understand these issues and find genetic causes. The goal is to improve diagnosis and care for these conditions.

This study aims to find out how many adults with cystic fibrosis smoke or vape. Researchers will survey 100 patients at a French hospital to get current data. The goal is to improve tobacco prevention and understand how smoking or vaping might affect newer cystic fibrosis treatme…

This study looks at whether sleep disorders make vertigo worse for people with Ménière's disease, a condition that causes hearing loss, ringing in the ears, and dizziness. Researchers will track 100 adults to see if those with more severe vertigo also have more sleep problems. Th…

This study looks at whether teaching delivery room staff how to better find and fix tears during childbirth can lower the chance of women having anal incontinence later. About 1,000 women who gave birth vaginally at a French hospital will be followed. The goal is to see if better…

This study is observing 100 women with polycystic ovary syndrome (PCOS) in Alsace, France to learn more about the condition. Researchers will measure things like obesity rates and insulin resistance to better understand the different types of PCOS. The goal is to improve diagnosi…

This study talks to family doctors in Bas-Rhin, France to find out what makes it hard for terminally ill patients to receive end-of-life care at home. About 80% of people wish to die at home, but many face obstacles like heavy workloads and emotional strain on doctors. The goal i…

This study reviews medical records of 2,450 women who had C-sections at a French hospital to find out why some still feel pain despite spinal anesthesia. Researchers aim to identify risk factors and improve pain management. No new treatments are tested—just learning from past cas…

This study looks at why people with axial spondyloarthritis often feel very tired and how that relates to muscle function. Researchers will measure exercise capacity in 122 adults starting a new targeted therapy. The goal is to better understand the connection between fatigue and…

This study looks at whether a questionnaire called AT HARM 10 can help identify emergency room visits caused by medication problems in adults over 65. Researchers will test the tool on 100 patients at one hospital to see how many drug-related issues they can find. The goal is to …

This study looks at why families refuse organ donation when asked, even though most people support it. Researchers at Strasbourg University Hospital will talk to families of 100 brain-dead patients to understand their reasons. The goal is to reduce refusals and help more people g…

This study is testing whether a simple symptom score questionnaire (SCST) is acceptable and useful for patients with allergic rhinitis during ENT check-ups. The goal is to see if this tool helps doctors monitor severity and response to treatment consistently. Thirty adults will p…

This study looks back at 100 adults treated for aerodigestive fistulas—abnormal connections between the airway and digestive tract—at Strasbourg University Hospital between 2014 and 2023. Researchers will review medical records to understand survival rates and how these rare, oft…

This study is testing a newer technique called cryobiopsy, which uses a freezing probe to take tissue samples from the lungs. The goal is to see how safe and accurate it is for diagnosing conditions like lung disease, tumors, or infections. Researchers at a French hospital will s…

This study compares the risk of heavy bleeding between surgical and medical abortions performed at 14 to 16 weeks of pregnancy. Researchers at Strasbourg University Hospital will enroll 50 adult women to see which method leads to fewer cases of blood loss over 500 cc. The goal is…

This study reviews 450 cases from Strasbourg University Hospital's emergency departments to see if staff follow 2021 French guidelines on physical restraint. Researchers will compare cases that follow the rules with those that don't, and look at who gets restrained, when, and why…

This study looks at 100 adults hospitalized in the ICU for a serious pulmonary embolism (a blood clot in the lung). Researchers want to know how long it takes for the blood thinner (unfractionated heparin) to reach a level that prevents more clots. They will also check if faster …

This study reviews medical records of 221 people with advanced melanoma who received immunotherapy between 2013 and 2021. The goal is to find new factors that predict which patients achieve a complete and lasting response. Participants must be 18 or older and have received treatm…

This study looks at 100 children under 18 who come to the emergency room with visible blood in their urine. The goal is to list the different causes and see how doctors currently manage this symptom. No new treatments are tested; the aim is to gather information to create better …

This study is testing a new, more powerful DNA reading technique (long-read sequencing) to find genetic causes of dystonia, a movement disorder causing muscle spasms. It involves 150 people with dystonia whose standard genetic tests came back normal. If successful, this could end…

This study surveys 100 French dentists who treat children to understand how they handle baby teeth with irreversible pulpitis or necrosis. Instead of always pulling the tooth, some dentists use a procedure called pulpectomy, which has high success rates. The goal is to learn what…

This study looks at medical records of 20 adults who had bariatric surgery and later received treatment for alcohol use disorder. Researchers want to understand if and how the surgery was considered during addiction follow-up. The goal is to improve care for patients with both co…

This study looks back at the medical records of 60 adults treated for adrenal cortex carcinoma at a French hospital. Researchers want to learn more about the disease's features and how long patients live after treatment. The goal is to better understand this rare cancer and impro…

This study looks at children whose parents had an extra genetic test (exome sequencing) during pregnancy because of ultrasound findings. Researchers want to see how these children develop after birth, especially when the test came back negative. The goal is to learn if a negative…

This study examines real-life cases where adults with psychotic disorders successfully reduced or stopped their antipsychotic medication. Researchers aim to understand when and how deprescribing can work safely, balancing the risk of relapse with the burden of side effects. The g…

This study looks at how emergency departments handle patients who have had a transient ischemic attack (TIA), also known as a mini-stroke. Researchers will review records of 300 adults diagnosed with TIA in 2024 to see if the care they received—like tests and treatments—matched t…

This study looks at blood clotting (hemostasis) in 1,000 healthy premature babies born before 37 weeks. Researchers want to know what normal clotting values are from birth to 18 months old, and whether they differ from full-term babies. The goal is to help doctors better interpre…

This study looks at adults aged 75 and older who come to the emergency room with a medical problem and need to be admitted to the hospital. Researchers want to see if being sent first to a Short-Stay Unit (a temporary holding area) affects their chances of survival three months l…

This study looks at how flexible brain activity is in people with Lewy body disease, a condition that causes thinking and behavior problems and is often hard to diagnose. Researchers will analyze past EEG recordings from 40 adults to see if certain brain patterns are linked to th…

This study looks at whether changes in blood cell function and stress markers can help doctors detect and predict the progression of pre-capillary pulmonary hypertension, a serious lung condition. Researchers will collect blood samples from 120 patients during routine visits over…

This study looks at whether certain medications that alter gut bacteria can influence how well immunotherapy works in people with advanced lung cancer. Researchers will review medical records from 800 adults to see if these drugs affect survival. The goal is to find ways to impro…

This study surveys 100 doctors and medical trainees in France to see how much they know about tick-borne encephalitis, a rare but serious brain infection spread by ticks. The goal is to find gaps in knowledge so that diagnosis and prevention can be improved, especially in areas w…

This study looks at whether common blood thinners (heparins) can mess up lab tests for another blood thinner called argatroban. Doctors often switch patients from heparin to argatroban, but current tests might not tell the two apart, risking bleeding or clots. Researchers will an…

This study collects information from about 100 adults in Alsace who have had a confirmed case of human anaplasmosis, a bacterial infection spread by ticks. Researchers want to learn more about how common it is, what symptoms people have, and how serious it can be. The goal is to …

This study looks at why some people with advanced bladder cancer receive older platinum-based chemotherapy instead of a newer, more effective drug combination. Researchers will review the medical records of 50 patients to understand the reasons behind these treatment choices. The…

This study looks at how people feel and function after surviving a severe abdominal emergency called acute mesenteric ischemia. Researchers will ask 100 adults treated at Strasbourg University Hospitals between 2010 and 2022 to fill out a quality-of-life questionnaire. The goal i…

This study looks at people with systemic scleroderma who also have a family member with the disease. Researchers want to understand how the disease runs in families and find clues that could lead to better treatments. About 20 adults will take part, and no new treatments are bein…

This study looks at 50 adults with unexplained bleeding to understand how low serotonin levels in platelets affect blood clotting. Researchers will use a bleeding questionnaire to measure symptoms. The goal is to gather knowledge, not to test a new treatment.

This study looks at whether continuously monitoring oxygen levels while moving patients from the operating room to the recovery area can prevent dangerous drops in oxygen. About 30 adults having surgery will take part. Researchers will compare oxygen readings taken at the start a…

This study interviews 15 doctors in Alsace, France, who treat elderly patients with osteoporosis and have used a practical guide on the condition. The goal is to find out what helps or prevents them from using the guide in their daily practice. By understanding these factors, res…

This study aims to describe a rare condition called panniculitis (inflammation of the fat under the skin) in people with dermatomyositis. Researchers will examine 20 participants aged 1 year and older to identify unique clinical and microscopic features. The goal is to better dis…

This study looks at 500 adults who had total knee replacement surgery to see if spinal anesthesia leads to better recovery than general anesthesia. Recovery is measured using a questionnaire called QoR-15F. The goal is to find out which method helps patients feel better sooner af…

This study looks back at medical records of 50 adults in France who were diagnosed with HIV between 2021 and 2024. Researchers want to find out if doctors missed signs of HIV during visits in the year before diagnosis. The goal is to understand why testing is delayed and help cat…

This study looks at how many women with Turner syndrome who want to become parents actually succeed, whether through natural pregnancy, egg donation, or adoption. Researchers will review medical records of 93 adult women treated at a French hospital between 2009 and 2019. The goa…

This study looks at whether measuring Aspergillus fumigatus DNA in blood or lung fluid can help predict outcomes in patients with invasive aspergillosis, a serious fungal lung infection. Researchers will track 100 adults to see if changes in PCR levels during treatment relate to …

This study will review the medical records of about 115 transgender people who started medical support before age 18 at Strasbourg University Hospital. The goal is to describe the care they received and their health outcomes. No new treatments are being tested; instead, researche…

This study looks at one adult with severe hemophilia A who is taking long-term blood thinners (anticoagulation). The goal is to understand how to balance bleeding risks from the blood thinner with the natural protection against clots from hemophilia. Newer clotting factor treatme…

This study looks at how a stay in the intensive care unit (ICU) affects a person's quality of life and risk of post-traumatic stress disorder (PTSD). Researchers will ask 40 adults who spent more than 48 hours in the ICU to fill out questionnaires about their experience and curre…

This study looks at 100 adults with type 2 diabetes who were admitted to the ICU with severe lactic acidosis. Researchers want to see if taking metformin before admission affects their chances of survival. The goal is to better understand the role of this common diabetes drug in …

This study reviews medical records of 400 adults hospitalized with a serious strep blood infection (Streptococcus anginosus). The goal is to identify factors linked to death within 28 days. No new treatments are tested; instead, researchers hope to learn what makes this infection…

This study surveys 269 healthcare professionals in Alsace, France, including psychiatrists, midwives, and general practitioners, to understand their knowledge and practices around eating disorders during pregnancy and the postpartum period. The goal is to identify gaps in care an…

This study explores using donated human placentas as a realistic, low-cost training tool for neurosurgeons learning to repair brain aneurysms. About 50 placentas will be used to assess surgical skill improvement. The goal is to provide hands-on practice without relying on animals…

This study looks at whether having total knee replacement surgery as an outpatient (going home the same day) leads to better recovery compared to staying in the hospital overnight. Researchers will review medical records of 440 adults who had knee replacement at a French hospital…

This study looks at how the way doctors talk about breech birth affects a mother's choice between vaginal delivery and C-section. Researchers will survey 200 women who gave birth to a breech baby in 2024 at French university hospitals, along with their doctors. The goal is to und…

This study surveys 100 healthcare professionals and students in Alsace, France, to understand their training, knowledge, and experience with organ donation. The goal is to find out if current training is sufficient, clear, and useful, and to identify misconceptions that may hinde…

This study looks at how often newborns who fail their hearing test have a hidden infection called cytomegalovirus (CMV). CMV is a common virus that can cause hearing loss and other health problems. The goal is to collect data to improve screening and follow-up care for these babi…

This study looks at whether medical students in their final year find it acceptable to receive training on how to certify a death and how to tell a family that their loved one has died. Twenty students from the University of Strasbourg will be asked about their views. The goal is…

This study looks at how well a particular type of knee replacement works in 960 adults who had surgery between 2013 and 2024. Researchers will check knee function and X-ray results at least one year after surgery. The goal is to see how the prosthesis performs and compare it to o…

This study surveys 50 pregnant women at the CMCO to understand their interest in and fears about ambulatory (walking) epidural anesthesia, a technique that allows more movement during labor. The goal is to learn what patients expect and worry about before the hospital introduces …

This study looks at whether nutritional status is linked to prognosis in adults with gastroenteropancreatic neuroendocrine tumors (NETs), which are slow-growing cancers of the digestive system. Researchers will assess malnutrition in 100 participants aged 18 to 70 who have been t…

This study looks back at how often and why antithrombin—a blood protein that helps prevent clots—was given to patients in intensive care or during surgery at Strasbourg University Hospitals over one year. Researchers will review records of 160 adults who received it to see if pre…

This study looks at how occupational health doctors and nurses in France identify police officers who may be struggling with mental health issues like depression, anxiety, or PTSD, and how they refer them to specialized care. About 200 health professionals who work with national …

This study looks at chest CT scans from 80 patients with a rare but serious fungal lung infection called pulmonary mucormycosis. Researchers want to see if certain patterns on the scans can predict whether a patient will get better or worse. The goal is to help doctors tailor fol…

This study looks at whether people who are more physically active before incisional hernia surgery have fewer problems afterward. Researchers will track 100 adults who already had the surgery and see if their activity level relates to complications. The goal is to understand if b…

This study looks back at the medical records of 30 immunocompromised patients (like organ transplant recipients or those on immune-suppressing drugs) who had toxoplasmosis. The goal is to understand how many are affected and how to better diagnose, treat, and prevent this infecti…

This study looks at cases of recurrent borreliosis, a bacterial infection spread by ticks or lice, that have been diagnosed in France. Researchers will describe the symptoms, where patients got infected, which Borrelia species caused it, and how it was diagnosed and treated. The …

This study looks at how different types of platelets change in adults who need ECMO (a machine that helps the heart and lungs). Researchers want to see if these changes can explain bleeding or clotting problems. The study will follow 75 patients in the ICU for one week after star…

This study looks at whether a special MRI scoring system called O-RADS can accurately predict if an ovarian mass in girls under 16 is cancerous or not. Researchers will review the MRI results of 100 girls who had surgery for ovarian masses. The goal is to help surgeons choose the…

This study surveys healthcare professionals in European dialysis centers to understand how they measure intraperitoneal pressure (belly pressure) in children with kidney failure who are on peritoneal dialysis. The goal is to learn about current practices and improve how dialysis …

This study looks back at the medical records of 400 full-term newborns who had very low cord blood pH (a sign of severe oxygen shortage during birth). Researchers want to find specific heart rate patterns that show when a baby is struggling and needs help. The goal is to help doc…