University Hospital, Strasbourg, France

This study tests if freezing tumors (cryoablation) works better than standard drugs for people with desmoid tumors that have grown after initial monitoring. About 150 participants will be randomly assigned to one of the two treatments. The goal is to see which approach better sto…

This study looks at whether clindamycin, an antibiotic taken by mouth, works as well as other antibiotics for treating Streptococcus infections in artificial joints. About 260 adults who had joint replacement surgery and developed an infection will be included. The goal is to see…

This study looks at whether a single surgery to replace an infected hip or knee joint works as well as the usual two-step approach for rare Candida fungal infections. Researchers will check infection clearance in 16 adults who had this one-stage procedure. The goal is to see if o…

This study looks at 830 people with relapsing-remitting multiple sclerosis (MS) that started after age 50. Researchers compare two treatment strategies: starting with a moderate medication and switching if needed, versus starting with a stronger medication right away. The goal is…

This study compares a new blood test, Cryocheck HexLA, to the current test used to detect lupus anticoagulant, a substance that increases the risk of blood clots. Researchers will test blood samples from 200 adults to see which test is more accurate and less affected by blood-thi…

This study looks at a newer biopsy method called cryobiopsy, which uses extreme cold to take tissue samples from the lungs. The goal is to see how well it diagnoses conditions like lung cancer, lymphoma, and scarring lung diseases, and to check its safety. About 30 adults who nee…

This study looks at whether giving pregnant women free organic vegetables and teaching them about healthy eating can lower their exposure to pesticides. About 210 pregnant women in Strasbourg will take part. Researchers will measure pesticide levels in urine to see if the program…

This study looks at whether nutritional status is linked to better outcomes in adults with slow-growing digestive neuroendocrine tumors. Researchers will check for malnutrition in 100 participants and see how it relates to their health. The goal is to find if improving nutrition …

This study looks at the risk of heavy bleeding in abortions done between 14 and 16 weeks of pregnancy. It compares two methods: surgery and medication. The goal is to help doctors and patients choose the safest option. About 50 women will take part at a hospital in France.

This study looks at whether continuously monitoring oxygen levels while moving patients from the operating room to the recovery area can prevent drops in oxygen. About 30 adults having surgery under general anesthesia will take part. Researchers will compare oxygen readings taken…

This study looks at cases of recurrent borreliosis, a bacterial infection spread by ticks or lice, that have been diagnosed in France. Researchers will describe the symptoms, where patients came from, the type of bacteria, and how the infection was found and treated. The goal is …

This study looks at how doctors at Strasbourg University Hospital treat severe stomach or intestinal bleeding in patients taking direct oral anticoagulants (blood thinners). Researchers will review the records of 250 adults to see how often a drug called prothrombin complex conce…

This study looks at whether medical students in their final year of school find it acceptable to receive training on how to officially confirm a death and tell family members. About 20 students will be asked about their views. The goal is to see if such training should be added t…

This study interviews 15 doctors in Alsace, France, who treat frail elderly patients with osteoporosis. The goal is to understand what makes them more or less likely to use a practical guide on managing the condition. The findings could help improve care and reduce fractures in o…

This study looks at how blood cells work and levels of oxidative stress in 120 people with pre-capillary pulmonary hypertension. Researchers want to see if these blood markers can help detect the disease and predict how it will progress. Participants give blood samples during rou…

This study interviews 12 general practitioners in Bas-Rhin, France to understand the barriers and supports for providing palliative care at home. Many people wish to die at home, but it often doesn't happen. The goal is to learn what makes it easier or harder for doctors to offer…

This study looks at children who had extra genetic testing (exome sequencing) during pregnancy because of ultrasound findings. Researchers want to see how these children develop after birth, especially when the test results were negative. The goal is to understand if a negative r…

This study asks 50 pregnant women at a French hospital about their interest in and worries about ambulatory (walking) epidural anesthesia. The goal is to understand what patients think before offering this technique more widely. No treatment is given—just a questionnaire to gathe…

This study is looking at 100 women with Polycystic Ovary Syndrome (PCOS) in Alsace, France to better understand the condition. PCOS is a common hormone problem that can cause irregular periods, fertility issues, and higher risk for diabetes. The researchers will measure how many …

This study looks at families where more than one person has systemic scleroderma, a rare autoimmune disease. By studying these families, researchers hope to find clues about how the disease develops and progresses. The study involves 20 adults with the condition and their first-d…

This study examines whether taking metformin before being admitted to the intensive care unit (ICU) affects survival in patients with type 2 diabetes who develop severe lactic acidosis. Researchers will review records of 100 adults admitted to a French hospital over a 10-year per…

This study looks back at medical records of 400 adults hospitalized with a severe strep blood infection (Streptococcus anginosus). The goal is to find out which factors are linked to a higher risk of death within 28 days. By identifying these factors, doctors hope to improve trea…

This study looks at what helps or hinders creating care plans for vulnerable patients in palliative care who live in medicalized residential facilities. Researchers will interview staff and others to understand the organizational, human, and relational factors involved. About 100…

This study looks back at medical records of 100 adults in France who had babesiosis, a rare tick-borne infection. Researchers want to learn more about who gets it, what symptoms they have, and how they were treated. The goal is to improve future diagnosis and care, especially for…

This study looks at whether a special MRI scoring system (O-RADS) can accurately predict if an ovarian mass is cancerous in girls under 16. About 100 participants who had surgery for an ovarian mass and a preoperative MRI will be included. The goal is to help doctors choose the r…

This study looks at medical records of 20 adults who had bariatric surgery and later received treatment for alcohol use disorder. Researchers want to understand how the surgery was considered during addiction follow-up. The goal is to improve care for patients with both condition…

This study looks back at the medical records of 115 transgender minors who started care at Strasbourg University Hospital before age 18. The goal is to describe the types of support they received, such as from child psychiatry or pediatric endocrinology. No new treatments are giv…

This study looks at whether a very fast spin (high-speed centrifugation) can separate fat from blood samples so doctors can accurately measure anti-Xa activity, a key test for monitoring blood thinners. About 150 adults on blood thinners will have their blood samples tested. If s…

This study tests a questionnaire called AT HARM 10 to help pharmacists identify when a patient's emergency visit is caused by their medications. Researchers will enroll 100 adults over 65 in the emergency department to see how well the tool works. The goal is to improve medicatio…

This study looks at how well a scoring tool called the HScore can diagnose hemophagocytic lymphohistiocytosis (HLH) in intensive care patients who also have liver failure or cirrhosis. Researchers will review medical records of 100 adults admitted to one hospital over ten years. …

This study looks at chest CT scans from 80 patients with a rare and serious lung infection called pulmonary mucormycosis. Researchers want to find patterns on the scans that could predict whether a patient will get better or worse. The goal is to help doctors choose the best trea…

This study looks at how doctors currently screen and treat obstructive sleep apnea (OSA) in children with Down syndrome. By reviewing past medical records of 30 children, researchers hope to create a simple guide to improve care. The goal is to help these children get better slee…

This study reviews medical records of 300 adults who had a transient ischemic attack (TIA), or mini-stroke, and visited the emergency department in 2024. Researchers want to see if the care patients receive—like tests and treatments—matches their actual risk of future problems. T…

This study aims to understand how many women with Turner syndrome who want to become parents actually succeed. Researchers will look at pregnancies (natural or through egg donation) and adoptions among 93 women treated at a French hospital. The goal is to describe outcomes, not t…

This study examines real-life cases of adults with psychotic disorders who are stable on long-term antipsychotics and choose to reduce or stop their medication. Researchers want to learn when and how deprescribing can succeed, and what challenges arise. The goal is to provide pra…

This study tracks 100 children under 18 who come to the emergency department with visible blood in their urine. Researchers want to learn the different causes of this symptom and how doctors currently manage it. The goal is to use this information to create a standard care protoc…

This study looks back at medical records of 30 adults with weakened immune systems (from organ transplants, cancer, or certain medications) who also had toxoplasmosis. The goal is to learn how many people are affected and how to better diagnose, treat, and prevent this infection.…

This study looks at whether how active people are before incisional hernia repair affects their risk of complications after surgery. Researchers will review data from 100 adults who had the operation. The goal is to see if being inactive and having other health issues leads to mo…

This study looks at 50 adults with unexplained bleeding to see if low serotonin levels in their platelets are linked to their condition. Researchers will use a standard bleeding questionnaire to measure symptoms. The goal is to better understand how serotonin affects bleeding ris…

This study looks back at the medical records of 400 full-term newborns who had very low cord blood pH (below 7.00) at birth, a sign of severe oxygen shortage. Researchers want to find patterns in fetal heart rate recordings that can help doctors spot when a baby is struggling ear…

This study looks at how well a certain type of knee replacement (a fixed polyethylene posteriorly stabilized cemented total knee prosthesis) works over at least one year. Researchers will review medical records and X-rays from about 960 adults who had this surgery between 2013 an…

This study tests a training tool for brain surgeons: a fresh human placenta. Its blood vessels look like those in the brain, and doctors can practice repairing bulging spots (aneurysms) on it. The goal is to improve surgical skills without using animals or expensive computer simu…

This study surveys 100 doctors and trainees in France to see how much they know about tick-borne encephalitis, a rare but serious disease spread by ticks. The goal is to find gaps in knowledge so that diagnosis and prevention can be improved. No treatment is given; it is purely a…

This study tests whether a special MRI scan can find early brain changes in professional soccer players who may be at risk for chronic traumatic encephalopathy (CTE) from repeated headers. Researchers will scan 80 male players aged 32 to 60 and compare them to people who never pl…

This study looks at whether sleep disorders make vertigo worse for people with Ménière's disease, a condition that causes hearing loss, ringing in the ears, and dizziness. Researchers will follow 100 adults from a French hospital to see if those with more severe vertigo also have…

This study surveys 269 healthcare professionals in Alsace, France—including psychiatrists, midwives, and general practitioners—to assess their knowledge and practices regarding eating disorders during pregnancy and the postpartum period. The goal is to identify gaps in care and i…

This study aims to find out how many adults with cystic fibrosis smoke or vape, either actively or passively. Researchers will survey 100 adults who get regular care at a specialized center in France. The goal is to gather current data to improve tobacco prevention and understand…

This study reviews medical records of 221 people with advanced melanoma who received immunotherapy between 2013 and 2021. The goal is to find new clues that predict who will have a complete response, meaning their cancer disappears entirely. By understanding these factors, doctor…

This study looks at how different types of platelets (blood cells that help clotting) change in adults who need a heart-lung machine (ECMO) for severe heart or lung failure. Researchers will take blood samples on days 1, 3, and 7 after starting ECMO to see if shifts in platelet t…

This study looks at blood clotting (hemostasis) in 1,000 premature infants born before 37 weeks. Researchers want to find out what normal clotting values are from birth to 18 months, and whether they differ from full-term babies. The goal is to help doctors better understand and …

This study looks at 100 patients in France who developed a severe form of Lyme disease after receiving anti-CD20 treatment (a type of medication that lowers the immune system). Researchers want to understand the symptoms, severity, and progression of the infection in these patien…

This study surveys 100 French dentists who treat children to understand their choices for managing non-vital baby teeth. It compares common extraction with alternatives like pulpectomy and LSTR. The goal is to collect data on current practices and decision-making criteria, not to…

This study aims to better understand Lewy body disease by examining brain activity patterns in 40 patients. Researchers will analyze EEG recordings to see if specific brain wave abnormalities are linked to this neurodegenerative condition. The goal is to improve understanding of …

This study looks at how sleep helps or hurts memory in children with certain types of epilepsy. Researchers will test memory in children with mild or severe epilepsy and compare them to children without epilepsy. The goal is to see if epileptic brain activity during sleep causes …

This study looks at 36 adults with type 1 diabetes who have received a pancreatic islet transplant. Researchers want to see if a continuous glucose monitor (CGM) can detect early loss of the transplanted cells' function. They will track a measure called "Time in Tight Range" (blo…

This study looks at why families refuse organ donation when asked, even though most people in France support it. Researchers will talk to families of 100 brain-dead patients in the ICU to understand their reasons. The goal is to reduce refusals and help more people get life-savin…

This study looks at whether common blood thinners (heparins) can mess up lab tests for another blood thinner (argatroban). When doctors switch patients from one blood thinner to another, accurate testing is crucial to avoid bleeding or clotting risks. Researchers will analyze blo…

This study aims to understand if changes in a specific blood or lung fluid test (PCR) for a serious fungal infection can predict how well a patient will respond to treatment. Researchers will look back at medical records from 100 adults who had this test at a French hospital betw…

This study reports on one adult with severe hemophilia A who is receiving long-term anticoagulation (blood thinners). Hemophilia A is a genetic bleeding disorder where blood does not clot properly. The goal is to share how this patient's clotting factor levels and bleeding risks …

This study looks at whether having knee replacement surgery as an outpatient (going home the same day) leads to better recovery compared to staying in the hospital. Researchers will measure recovery using a questionnaire called QoR-15F. About 440 adults who had knee replacement a…