Researchers dig into past records to find clues for melanoma immunotherapy success
NCT ID NCT07302607
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study reviews medical records of 221 people with advanced melanoma who received immunotherapy between 2013 and 2021. The goal is to find new factors that predict which patients achieve a complete and lasting response. Participants must be 18 or older and have received treatment at Strasbourg University Hospitals. The study does not involve new treatments or direct benefits to participants.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 221 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2024
- Expected to finish
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Jan 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult subject with unresectable stage III or stage IV melanoma according to the AJCC classification - 8th edition;
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years; * Unresectable stage III or stage IV melanoma according to the AJCC classification - 8th edition; * Curative immunotherapy treatment (anti-PD-1 and/or anti-CTLA-4); * Treatment and follow-up at the Dermatology Department of the Strasbourg University Hospitals; * Immunotherapy initiated between January 1, 2013, and December 31, 2021. Exclusion Criteria: * Primary choroidal melanoma; * Adjuvant-intent immunotherapy; * Less than 3 months of follow-up after the start of immunotherapy; * Change of treatment before the first reassessment; * Treatment and follow-up at a department other than the Dermatology Department of the Strasbourg University Hospitals.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Service de dermatologie - Réanimation - CHU de Strasbourg - France
RECRUITINGStrasbourg, 67091, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a DNA vaccine teach the immune system to hunt melanoma?
- Can an immune booster make chemo hit melanoma harder?
- A quest to find biomarkers that match melanoma patients with the right immunotherapy
- Can a triple immunotherapy attack beat advanced melanoma?