University Hospital, Montpellier

This study tested a smartphone app called EkiYou V2, designed to help adults with diabetes who take multiple daily insulin injections. For six weeks, the app provided advice on how much insulin to take with meals and for background needs, automatically adjusting its suggestions o…

This study tested whether doctors could safely give fewer blood transfusions during heart surgery by using a special monitor that checks how much oxygen the body's tissues are using. Researchers compared two groups of 676 adult heart surgery patients: one group received transfusi…

This study tested whether a common heart valve replacement procedure could be done safely without first stretching the valve with a balloon. Researchers compared the standard method (with balloon stretching) against a simpler method (direct valve placement) in 250 patients with s…

This study tested whether adding a smartphone-based rehabilitation program to standard CPAP therapy could help obese adults with severe sleep apnea better manage their condition. 180 participants were randomly assigned to receive either the telerehab program plus CPAP or CPAP alo…

This study tested whether a noninvasive breathing mask could help patients who develop serious breathing problems after abdominal surgery. Researchers compared this mask approach to standard oxygen therapy in 300 patients across multiple hospitals. The goal was to see if the mask…

This study tested whether a 6-week self-management education program could improve the quality of life for people with long-term health conditions who face social or economic disadvantages. It involved 235 participants, including patients and caregivers, across five European coun…

This study tested whether adding a specific pain medication (Ultiva/remifentanil) to a standard drug (lidocaine) could improve feticide procedures. Feticide is a required step in terminating a pregnancy after 22 weeks. The trial involved 66 women and aimed to see if the new combi…

This study tested whether a mobile phone app for remote rehabilitation could help people with COPD maintain the benefits of a short-term exercise and education program. 200 patients who completed a 4-week in-person rehab program were randomly assigned to either use the mobile app…

This study tested whether a single injection of a patient's own stem cells, taken from their body fat, could help treat painful knee arthritis. It compared two different doses of these cells against a placebo injection in 100 people whose knee pain hadn't improved with standard t…

This study tested whether regularly checking the level of anti-TNF drugs in a patient's blood helps manage Crohn's disease and ulcerative colitis more effectively. 260 patients were split into two groups: one where doctors used these blood test results to adjust treatment, and on…

This study tested a new, less invasive surgical technique for breast reconstruction after preventive mastectomy. It involved 20 women at high genetic risk for breast cancer. The goal was to place the implant using a small camera through a single incision in the armpit, avoiding t…

This study tested a French national support program (PRADO) for patients after a heart failure hospitalization. It aimed to see if better coordination between doctors and nurses for 2-6 months could reduce costly hospital readmissions and deaths. The research involved 404 patient…

This study aimed to find out if using general anesthesia (being fully asleep) is as safe as using local anesthesia with sedation (being numbed and drowsy) for a common heart valve replacement procedure. It involved 218 patients with severe aortic valve narrowing. Researchers comp…

This study tested whether combining two therapies could help people regain arm function long after a stroke. Researchers gave 58 chronic stroke patients a rehabilitation program using virtual reality games, with some also receiving a gentle, targeted brain stimulation called HD-t…

This study aimed to create a better testing method for penicillin allergies. Researchers analyzed past patient data to design a new, simpler testing protocol. They then tested this new method on patients to see if it was as safe and accurate as current methods, but potentially fa…

This study tested a new method to help surgeons locate small, hidden breast tumors during surgery. Ten women with non-palpable breast cancer received both a new fluorescent dye injection and the standard radioactive marker before surgery. Researchers compared how well the glowing…

This study aimed to find better ways to diagnose a tricky form of heart failure that is common in older adults. Researchers tested a combination of five different markers in the blood of 91 participants to see if they could more accurately identify this specific condition. The go…

This study tested whether specific proteins in the blood can accurately diagnose Alzheimer's disease. Researchers compared blood test results from 342 patients with results from the current standard spinal fluid test and clinical assessments. The goal was to see if a less invasiv…

This study tested whether giving doctors the results of a specific blood test (ST2) could help them better manage patients hospitalized for heart failure. The goal was to see if using this information could reduce the number of patients who need to be readmitted to the hospital w…

This study tested a new, safer blood test for pregnant women to check if their unborn baby has inherited a serious genetic disease like Huntington's. It aimed to see if this simple blood draw could be as accurate as riskier tests like amniocentesis, which carries a small chance o…

This study aimed to prevent breathing failure in obese patients after they had a breathing tube removed in the intensive care unit (ICU). It compared two types of non-invasive breathing support to standard oxygen therapy to see which was better at keeping patients from needing th…

This study tested whether gentle osteopathic treatments could prevent flat head syndrome in newborns at risk. Researchers followed 101 infants for four months, comparing those who received osteopathic sessions to those who did not. The goal was to see if early manual therapy coul…

This study tested whether a balance rehabilitation program using virtual reality (VR) goggles is as effective as the standard therapy using specialized balance equipment. It involved 76 adults with vestibular disorders causing dizziness and balance problems. Researchers compared …

This study tested whether group-based cognitive training helps people with schizophrenia manage thinking problems that affect daily life. 218 patients with schizophrenia for less than 10 years were randomly assigned to receive either the cognitive training program or their usual …

This study tested whether different electronic distractions could help reduce common discomforts experienced by awake patients in the Intensive Care Unit (ICU). Researchers compared music therapy, two types of virtual reality, and standard devices like TV/radio to see which was m…

This study tested whether watching a video of themselves recorded during a severe psychotic episode could help people with schizophrenia better understand their illness. 60 patients were randomly assigned to either watch their video or receive standard care. Researchers measured …

This study tested whether a new mindful eating program could help French adults with overweight or obesity. 56 participants were randomly assigned to either the 8-week mindful eating program or a standard dietary advice program. The researchers compared changes in eating habits, …

This study looked at how corrective surgery for funnel chest (pectus excavatum) affects patients' heart and lung function during exercise and their overall quality of life. Researchers followed 43 patients, measuring their fitness and well-being before and after their surgical pr…

This small pilot study explored whether a mindfulness meditation program could help reduce the embarrassment and impact of hand tremors in people with Parkinson's disease. Researchers monitored 21 participants, some practicing mindfulness and others receiving usual care, using sm…

This study tested whether a mindfulness training program could help people manage pain from hip or knee osteoarthritis. Forty participants with moderate to severe pain were randomly assigned to either the mindfulness course or a control group. Researchers measured changes in pain…

This study aimed to understand how the in vitro fertilization (IVF) process affects the quality of life of women who are employed. Researchers followed 200 working women in France during their first IVF attempt, using questionnaires to track their emotional well-being, anxiety, d…

This study aimed to understand why people with a specific gene mutation (RANBP2) develop a severe, often fatal brain swelling called Acute Necrotizing Encephalopathy (ANE1) after common infections like the flu. Researchers compared blood samples from 35 people with the mutation t…

This study looked at whether following current medical guidelines for treating a specific type of heart attack (NSTEMI) leads to better patient recovery. Researchers observed 407 patients to see if having a key diagnostic procedure (coronary angiography) within 24 hours of diagno…

This study aimed to understand why some severe asthma patients don't respond well to the medication mepolizumab. Researchers measured drug levels in the blood of 50 patients who were already receiving this treatment. They compared drug concentrations between patients who responde…

This study aimed to create a laboratory model of the bronchial airways using stem cells from patients with severe asthma. Researchers took blood cells from four participants and turned them into stem cells, which were then grown into lung-like tissue. The goal was to build a tool…

This study aimed to discover new genes that cause hypospadias, a condition where the opening of the urethra is not at the tip of the penis. Researchers analyzed the DNA of 60 patients from families with multiple cases of hypospadias. The goal was to improve understanding of the c…

This study tested if adding a bendable guide wire (called a stylet) inside a breathing tube helps doctors place it correctly on the first try in critically ill adults. It involved over 1,000 patients in intensive care units who needed help breathing. The goal was to see if this c…

This study aimed to understand if drops in blood sugar trigger binge eating episodes in people with bulimia or binge eating disorder. Researchers tracked 20 participants for two weeks using continuous glucose monitors and food diaries. The goal was to gather information to potent…

This study aimed to understand how treating sleep apnea might help people who also have heart disease. Researchers tested if using a CPAP machine (a device that helps with breathing during sleep) for three months could reduce a type of body stress called oxidative stress in 28 pa…

This study aimed to understand if people with unusual forms of multiple sclerosis (MS) have a different or more severe disease process. Researchers compared blood levels of specific proteins (neurofilament light chain and GFAP) in 15 patients with atypical MS to 30 patients with …

This study aimed to find new markers in the blood to help understand and diagnose Sjögren's syndrome, an autoimmune disease that causes severe dryness. Researchers compared blood samples from 40 women with either Sjögren's syndrome or a related condition called scleroderma. They …

This study aimed to understand if extreme endurance exercise, like a long-distance triathlon, causes temporary heart damage and increases the risk of dangerous irregular heartbeats. Researchers followed 72 healthy male triathletes during the Embrun triathlon, checking their heart…

This study tested a new approach for managing narrowed heart arteries in patients who had a TAVI procedure to replace a stiff heart valve. Researchers wanted to see if using a special heart scan to check for poor blood flow *after* the valve replacement could safely guide decisio…

This study aimed to understand why children with birth-related arm paralysis often develop stiff shoulders. Researchers collected small muscle samples from eight children during planned shoulder surgery. They grew these cells in a lab to study their ability to repair and regenera…

This study aims to collect detailed information about breast skin to build a more accurate 3D computer model. The model is intended to help surgeons visualize tumors and plan operations for breast cancer patients. Researchers measured skin elasticity and thickness in 200 women an…

This study aimed to understand what makes it hard to place a breathing tube in critically ill adults in the Intensive Care Unit (ICU) and what complications can happen. Researchers observed over 1,400 intubation procedures across more than 50 hospitals to identify common risk fac…

This study aimed to find biological markers in sputum (mucus coughed up from the lungs) that could help predict how severe lung disease might become in people with cystic fibrosis. Researchers studied 50 participants, aged 12 to 30, who have cystic fibrosis. They collected sputum…