OSTEOPOROSIS

This study tested whether alendronate, a drug used for osteoporosis, can improve bone density in people with HIV who also have weak bones. About 140 participants received either alendronate or a placebo for two years, along with calcium and vitamin D. The main goal was to measure…

This study looked at whether eating Greek yogurt for 8 weeks could improve bone health and lower inflammation in adults aged 55 and older. Some participants also took exercise classes. The goal was to see if yogurt, with or without exercise, helps the body build stronger bones an…

This study tested whether denosumab, a drug given as a shot every 6 months, can improve bone density and prevent fractures in people with osteoporosis caused by systemic mastocytosis. The trial enrolled 24 adults with indolent systemic or cutaneous mastocytosis and osteoporosis. …

This study looked at 44 postmenopausal women and men over 50 with osteoporosis who had been on denosumab for at least three years. Researchers tested whether switching to alendronate or zoledronate could prevent bone mineral density loss. The goal is to find the best way to maint…

This study looked at 54 people who need long-term steroids and have weak bones (osteoporosis). It compared two treatments: first romosozumab then denosumab, versus denosumab alone for two years, then followed everyone on denosumab for two more years. The goal was to see which app…

This study tested a 12-week program of exercise (resistance, aerobic, balance, and flexibility training) plus a nutritional supplement containing HMB in 13 people with both osteoporosis and sarcopenia (muscle loss). Participants were split into two groups: one received the progra…

This study tested whether a single dose of zoledronic acid, a drug already used for osteoporosis, can prevent the rapid bone loss that often follows a spinal cord injury. Researchers measured bone density and strength in 60 adults who had recently lost the ability to walk. The go…

This study looked at 45 adults with osteoporosis caused by long-term steroid use. Participants had been taking denosumab and were switched to either zoledronic acid or alendronate at different times. The goal was to see which switch timing best controlled bone turnover and preven…

This study tested whether a bone-building drug (teriparatide) and whole-body vibration could help restore bone lost after spinal cord injury. 60 adults with chronic SCI and low bone density received one or both treatments for 12 months. The goal was to see if these approaches cou…

This study looked at whether combining a Mediterranean diet with progressive resistance training (like lifting weights) could improve bone density and bone health in people aged 65 and older. 47 older adults took part, with one group following the diet and exercise program for 12…

This study tested whether a monthly injection called romosozumab can improve bone health in women with chronic spinal cord injury and osteoporosis. Twelve women received the injections for one year, followed by a year of weekly alendronate pills. The goal was to see if the treatm…

This pilot study tested whether a telehealth program combining strength training, balance exercises, and nutrition advice could help older men at high risk for falls and fractures. Forty-five men aged 60 and older participated. The goal was to see if the program was practical and…

This study tested whether a short questionnaire given to women aged 50-80 during a hospital stay could help find those at risk for osteoporosis. Over 3,200 women took part. Those with risk factors were offered a bone density scan and, if needed, a referral to a specialist. The go…

This study looked at whether taking a soluble corn fiber supplement for one year could improve bone health in healthy adolescents aged 10-13. Participants were randomly assigned to receive the fiber supplement, with or without extra calcium, or a placebo. The goal was to see if t…

This study tested whether a virtual rehabilitation program called VIVA is practical for people who have had a spine fracture from osteoporosis. The program includes weekly online sessions to help reduce pain and improve movement and quality of life. The study involved 34 particip…

This study looked at whether playing balance games on a Wii Fit board could help women with osteoporosis who had a mastectomy. Sixty women participated, and their balance was measured before and after eight weeks of playing the games. The goal was to see if this fun, low-cost app…

This study looked at whether moderate aerobic exercise or resistance exercise is better for improving bone density in postmenopausal women with type 2 diabetes and osteoporosis. Fifty women aged 50 to 60 with a BMI of 30-35 took part. The goal was to see which type of exercise he…

This study tested a new CT-based method to measure bone health and fracture risk in 560 current or former smokers with and without COPD. The goal was to see if detailed bone structure scans could predict fractures better than standard bone density tests. Researchers hope this too…

This study followed 215 people newly diagnosed with HIV in Hong Kong to see how often they developed non-AIDS conditions like high blood pressure, diabetes, bone thinning, and kidney problems. Participants were checked before starting HIV treatment and again after 48 and 96 weeks…

This study looked at whether osteoporosis patient education programs in Danish municipalities improve patients' lives. Researchers compared over 3,000 people who took part in these programs with a similar group who did not. They measured quality of life, fractures, daily function…

This study followed 180 people with anorexia for 4 years to track changes in bone density and understand how fat-related hormones (like leptin and adiponectin) affect bone loss. Researchers measured bone density and blood markers every two years. The goal was to learn more about …

This study looked at whether working night shifts for a few days can change how your body builds and breaks down bone. Twenty healthy adults aged 20-40 were studied during simulated night shifts. Researchers measured bone markers in the blood to see if the body's natural sleep-wa…

This study looked at how teriparatide, a bone-building drug, works in 19 postmenopausal women with osteoporosis. The goal was to understand the changes in bone density and turnover over two years. The findings could help researchers develop better treatments for osteoporosis in t…

This study tracked 82 postmenopausal women with rheumatoid arthritis to see how their bone density changed over time. Researchers compared the effects of different arthritis medications and osteoporosis treatments on bone health. The goal was to understand which approaches might …

This study tested whether short, AI-made videos could help people aged 45 and older learn more about osteoporosis and improve their digital health skills. Sixty participants watched the videos and completed questionnaires before and after. The goal was to see if this easy-to-shar…

This study examined 549 older adults to see if there is a connection between metabolic syndrome and vitamin D levels. Researchers collected health information and blood samples from participants aged 65 and older. The goal was to understand how these factors relate, not to test a…

This study measured bone density in the hips of 44 stroke patients to see how paralysis affects bone strength. Researchers compared the paralyzed side to the non-paralyzed side and looked at muscle strength. The goal was to understand bone loss after stroke, not to test a treatme…

This study looked at how a natural cell cleanup process called autophagy might be linked to bone loss in older women. Researchers compared bone samples from women with osteoporosis (some with Alzheimer's disease) to healthy controls. The goal was to understand if poor autophagy c…

This study followed 59 nurses during their first year of work to see if working night shifts affects bone health compared to day shifts. Researchers measured bone turnover markers and bone density at the start and after one year. The goal was to understand if night shift work is …

This study looked at 70 elderly women, some with osteoporosis and some without, to see if leg muscle strength is linked to bone density. Researchers measured hip and knee muscle strength and compared it to bone mineral density. The goal was to better understand risk factors for m…

This study tested whether using regular CT scans (taken for other reasons) can help predict who is at risk for spine fractures better than the current standard method. Researchers looked at bone density and existing fractures in CT images from nearly 2,800 older adults over five …

This study tested whether a specialized CT scan (DECT) can better predict bone fractures in women with osteoporosis than the standard bone density test (DEXA). Researchers scanned the spine of 7 women aged 60 or older to analyze the inner bone structure. The goal was to develop a…

This study looked at how fat cells in bone marrow might contribute to bone loss in osteoporosis. Researchers took bone samples from 20 adults during hip replacement surgery and grew bone-forming cells in the lab. They then exposed these cells to substances released by fat cells t…

This study looked at different methods to screen male veterans for osteoporosis, a condition that weakens bones and raises fracture risk. Over 3,500 high-risk men took part, and researchers compared how well each screening approach worked. The goal was to find the most effective …

This early-stage study tested several new oral tablet versions of a bone-building hormone (hPTH(1-34)) in 45 healthy men aged 18-35. The goal was to see how well the body absorbs these new tablets compared to an existing oral tablet and a standard injection. The study focused on …