OSTEOPOROSIS
Clinical trials for OSTEOPOROSIS explained in plain language.
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Bone drug reveals hidden strength: new imaging shows structure improvements beyond standard scans
Disease control OngoingThis study looks at how teriparatide, a bone-building drug, affects the inner structure of bones in 100 men and women with osteoporosis over 24 months. Using a special 3D scanner, researchers measure changes in bone thickness and microarchitecture at the wrist and shin. The goal …
Matched conditions: OSTEOPOROSIS
Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 26, 2026 02:58 UTC
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Online tool for fracture patients fails to launch: study withdrawn
Disease control TerminatedThis study aimed to see if a web-based service (e-FLS) could help more people over 60 start osteoporosis treatment within a year after a low-trauma fracture, compared to standard fracture liaison services. The study was withdrawn before enrolling any participants, so no results a…
Matched conditions: OSTEOPOROSIS
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated May 26, 2026 02:52 UTC
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New osteoporosis drug copycat tested in healthy volunteers
Disease control ENROLLING_BY_INVITATIONThis study compares a new experimental drug, SAL023, to an approved osteoporosis medicine called Evenity. It involves 118 healthy Chinese adults aged 18 to 45. The goal is to see if the new drug works similarly in the body and is as safe as the approved one.
Matched conditions: OSTEOPOROSIS
Phase: PHASE1 • Sponsor: Shenzhen Salubris Pharmaceuticals Co., Ltd. • Aim: Disease control
Last updated May 26, 2026 02:52 UTC
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Nurse-led health program aims to empower midlife women in hong kong
Disease control OngoingThis study tests whether a nurse-led program can help women aged 45-64 in Hong Kong better manage their health and use medical resources wisely. Over 1,700 participants will either receive personalized nurse guidance or general health advice. The goal is to improve health confide…
Matched conditions: OSTEOPOROSIS
Phase: NA • Sponsor: The University of Hong Kong • Aim: Disease control
Last updated May 26, 2026 02:47 UTC
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Stem cells aim to strengthen bones in High-Risk women
Disease control OngoingThis early-stage study tests a new stem cell treatment (HMM910) in 9 postmenopausal women with osteoporosis who are at high risk of breaking a bone. The main goal is to see if the treatment is safe and tolerable. Researchers will also check how the stem cells move through the bod…
Matched conditions: OSTEOPOROSIS
Phase: PHASE1 • Sponsor: HELP Therapeutics Co., Ltd. • Aim: Disease control
Last updated May 22, 2026 13:53 UTC
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New study tests bone drug prolia in chinese men with osteoporosis
Disease control OngoingThis study looks at how well the drug Prolia works and how safe it is for men with osteoporosis in mainland China. About 102 men aged 30 to 90 with low bone density or a history of fractures will receive Prolia injections. The main goal is to see if bone density in the lower spin…
Matched conditions: OSTEOPOROSIS
Phase: PHASE4 • Sponsor: Amgen • Aim: Disease control
Last updated May 20, 2026 11:56 UTC
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New combo therapy aims to strengthen bones in elderly women
Disease control OngoingThis study tests whether giving older women (65+) in long-term care a monthly bone-building injection for one year, followed by an annual infusion, can improve bone density and prevent fractures. The goal is to find a better way to manage osteoporosis and reduce fracture risk in …
Matched conditions: OSTEOPOROSIS
Phase: PHASE4 • Sponsor: Susan L. Greenspan • Aim: Disease control
Last updated May 20, 2026 11:54 UTC
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Bone drug boosts spine surgery success in osteoporosis patients
Disease control OngoingThis study looks at whether taking teriparatide for one month before lumbar fusion surgery helps screws grip stronger in patients with osteoporosis. The goal is to reduce complications like screw loosening. 192 participants will be randomly assigned to receive the drug or not, an…
Matched conditions: OSTEOPOROSIS
Phase: NA • Sponsor: The University of Hong Kong • Aim: Disease control
Last updated May 19, 2026 12:00 UTC
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Could a bone drug help women with myeloma-related bone loss?
Disease control OngoingThis early-phase study tests whether romosozumab, a drug used for osteoporosis, can safely improve bone health in postmenopausal women who also have multiple myeloma. Ten participants receive the drug, and researchers measure changes in bone formation and breakdown markers. The g…
Matched conditions: OSTEOPOROSIS
Phase: PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 19, 2026 11:49 UTC
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New hope for bone loss after spinal injury: drug combo may protect knees
Disease control OngoingThis study compares two osteoporosis medications—romosozumab followed by denosumab versus denosumab alone—in 40 adults with a spinal cord injury that happened less than six months ago. The goal is to see which approach better maintains bone density around the knee over two years.…
Matched conditions: OSTEOPOROSIS
Phase: PHASE4 • Sponsor: James J. Peters Veterans Affairs Medical Center • Aim: Disease control
Last updated May 18, 2026 12:13 UTC
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New program aims to stop the fracture cycle in seniors
Disease control OngoingThis study looks at a program to help older adults get tested and treated for osteoporosis after breaking a bone. Many people don't realize a fracture can be a warning sign of weak bones, and without care, they are at high risk for more breaks. The program notifies doctors and pa…
Matched conditions: OSTEOPOROSIS
Phase: NA • Sponsor: University of Manitoba • Aim: Disease control
Last updated May 18, 2026 12:02 UTC
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New bone drug may reveal hidden fracture risks
Disease control OngoingThis study looks at how teriparatide, a drug that builds new bone, changes bone structure in 60 postmenopausal women with severe osteoporosis over two years. Researchers want to see if the drug affects bone thickness differently at the wrist versus the ankle, which could help pre…
Matched conditions: OSTEOPOROSIS
Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Osteoporosis drug showdown: which works better for Age-Related bone loss?
Disease control ENROLLING_BY_INVITATIONThis study tests whether switching osteoporosis patients from one drug to another after one year improves bone loss. It involves 40 adults aged 45 and older who already completed a related trial. Participants will take either Alendronate or Teriparatide for one year, then switch …
Matched conditions: OSTEOPOROSIS
Phase: PHASE4 • Sponsor: Paul F Netzel • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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New study aims to stop dangerous falls in seniors after a broken bone
Prevention ENROLLING_BY_INVITATIONThis study looks at three different care models to help prevent falls and further broken bones in older adults (65+) who are recovering from a fracture in a skilled nursing facility. The models focus on reducing risky medications, improving bone health, or both. Researchers want …
Matched conditions: OSTEOPOROSIS
Phase: NA • Sponsor: Duke University • Aim: Prevention
Last updated May 26, 2026 02:58 UTC
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Lifting weights may ward off brittle bones and achy joints in women over 50
Prevention OngoingThis study looks at whether different types of resistance exercise (like lifting weights) can help prevent osteoporosis (weak bones) and osteoarthritis (joint pain) in women aged 50 to 70 who have gone through menopause. Researchers will measure changes in bone density, muscle si…
Matched conditions: OSTEOPOROSIS
Phase: NA • Sponsor: Loughborough University • Aim: Prevention
Last updated May 22, 2026 14:03 UTC
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Osteoporosis bone test study pulled before it began
Knowledge-focused TerminatedThis study aimed to see if a special bone assessment technique could predict how well bone status improves after a zoledronic acid infusion in women with osteoporosis. It planned to measure bone texture and density before and after treatment. However, the study was withdrawn befo…
Matched conditions: OSTEOPOROSIS
Phase: NA • Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated May 26, 2026 03:02 UTC
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New bone probe may spot fracture risk better than standard scans
Knowledge-focused OngoingThis study tests a new, less invasive way to measure bone strength in women who have had hip or wrist fractures. Researchers want to see if this method can identify fracture risk better than standard bone density scans. About 190 women will participate, including those with recen…
Matched conditions: OSTEOPOROSIS
Phase: NA • Sponsor: Beth Israel Deaconess Medical Center • Aim: Knowledge-focused
Last updated May 26, 2026 02:55 UTC
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Bone secrets: could your skeleton control kidney health?
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at how bone might influence citrate levels in urine, which is important for kidney stone prevention. Researchers will study 25 people with osteoporosis who have not yet been treated. They will measure bone density, bone turnover, and urine citrate before and afte…
Matched conditions: OSTEOPOROSIS
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated May 26, 2026 02:53 UTC
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Osteoporosis drugs may also strengthen muscles in seniors
Knowledge-focused OngoingThis study looks at whether medications for osteoporosis also improve muscle health in adults aged 65 and older who have both bone loss and muscle loss (sarcopenia). Researchers will measure changes in muscle mass, strength, walking speed, and bone density over time. The goal is …
Matched conditions: OSTEOPOROSIS
Phase: PHASE4 • Sponsor: Nami Safai Haeri • Aim: Knowledge-focused
Last updated May 22, 2026 13:51 UTC