Spinal injury patients may keep stronger bones with simple infusion

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * In-patient at Rehabilitation Institute of Chicago (RIC) or an outpatient who was recently discharged from RIC * Males and females * Age \>/=18 years * Medically stable in the opinion of subject's physiatrist * SCI at within 120 days inclusive at time of screening * SCI with inability to ambulate independently * ASIA Impairment Scale (AIS) A, B, or C, at time of study entry * Capable of positioning to have DXA performed * Able to tolerate acetaminophen * No known endocrinopathies (diabetes type 1 or 2 can be included) * Normal TSH levels * Normal 25-OH vitamin D levels (\>/= 20 ng/ml) at baseline (subjects may be repleted) * Normal calcium levels * Normal renal function (creatinine \<2.0 mg/dl) * Well hydrated with adequate intake of liquids * Able to return for all follow-up visits * Capable of reading and understanding informed consent document * Males and females of childbearing potential must be willing and able to use double barrier method of contraception for 2 months after having received study drug Exclusion Criteria: * Have Paget's disease of the bone * Malignancy as a cause of acute SCI * Have unexplained high levels of alkaline phosphatase in blood * Any active gastrointestinal condition that results in malabsorption * Poor dental hygiene or requirement for invasive dental procedure within two months prior to enrollment * History of bone metastasis and skeletal malignancies * History of alcoholism or drug abuse within the 2 years prior to study screening * Other medical conditions that in the opinion of the investigator would preclude the subject from completing the study * Elevated liver function tests \>2x normal * Currently being prescribed anti-convulsants at a dose or frequency that is determined to interfere with bone metabolism as determined by the investigator * Currently being prescribed glucocorticoids, other than inhaled glucocorticoids * Current or recent use any bone-active agents, including any bisphosphonate, raloxifene, hormone therapy (estrogen and estrogen/progestin), calcitonin or strontium-containing compounds within 60 days of screening. * Pregnant, planning to become pregnant, or lactating