OBSTRUCTIVE SLEEP APNEA

This study looked at whether using a CPAP machine to treat sleep apnea soon after a stroke can help the heart and lower the chance of another stroke. About 71 people who had a stroke and also had moderate to severe sleep apnea took part. Researchers measured changes in heart size…

This study tested a daily pill called lorundrostat in 48 adults with moderate-to-severe sleep apnea and high blood pressure. The goal was to see if the drug could reduce breathing pauses during sleep and lower nighttime blood pressure. Participants were randomly assigned to recei…

This study looked at whether a drug called bosentan could lower blood pressure in people with sleep apnea as effectively as the standard treatment, CPAP. Nineteen adults with sleep apnea and mild high blood pressure took part. The goal was to see if blocking a certain chemical in…

This study tested whether acetazolamide, a cheap and well-tolerated water pill, can reduce sleep apnea severity and improve blood pressure in young adults (18–50 years old) who cannot or will not use a CPAP mask. 54 participants received either the drug or a placebo for two weeks…

This study tested whether orofacial myofunctional therapy (OMT) — simple tongue and throat exercises done during the day — can improve breathing during sleep in people with mild-to-moderate obstructive sleep apnea. 209 adults with sleep apnea were assigned to either OMT or a sham…

This study looked at whether chemicals in the blood (metabolomics) can help diagnose obstructive sleep apnea and show if treatment with a CPAP machine is working. Researchers studied 388 adults with and without sleep apnea. They collected blood samples and tracked CPAP use to see…

This study tested a new approach for people with obstructive sleep apnea who struggle to use their CPAP machine. Many patients stop using CPAP because they wake up easily. Researchers gave a safe sleep medication to 42 adults to see if it would help them sleep more soundly and us…

This study tested how easy a new CPAP mask (the Eclipse) is to use compared to a traditional mask. 70 adults with sleep apnea tried both masks at home. Researchers measured how many people needed help, how much they liked the mask, and any technical problems.

This study tested whether a mindfulness-based program could help teenagers with moderate to severe obstructive sleep apnea use their CPAP machine more consistently. Thirty-seven teens aged 13-18 took part, comparing mindfulness training to online peer support. The goal was to see…

This study tested a myofunctional therapy nozzle that fits on a water bottle. By drinking through it daily, users exercise mouth and tongue muscles to potentially improve obstructive sleep apnea and snoring. 43 adults with mild to moderate sleep apnea participated, tracking their…

This study tested whether a 3-day course of the oral steroid dexamethasone can reduce the severity of obstructive sleep apnea (OSA) in children aged 2 to 10. Ten children with moderate to severe OSA received either the drug or a placebo, and their breathing during sleep was measu…

This study tested a new CPAP mask called DreamPort-Eclipse against a traditional nasal mask in 173 adults with obstructive sleep apnea. The goal was to see if the new mask reduced air leaks, improved breathing pauses (AHI), and required lower pressure. Participants used their usu…

This early-phase study tested whether the drug acetazolamide can reduce the severity of breathing pauses that occur during REM sleep in people with obstructive sleep apnea (OSA). Eleven adults with REM-predominant OSA who were not using CPAP took part. Researchers measured change…

This study tested whether sleeping in a semi-upright position (propped up) instead of lying flat on the back could prevent sleep apnea from getting worse on the second night after surgery. 164 adults with sleep apnea who were having inpatient surgery took part. The goal was to se…

This study tested a new nasal mask (F&P Caramel) for people with obstructive sleep apnea. 45 adults who already used a similar mask tried it at home for 14 days. Researchers checked how well it controlled breathing pauses and daytime sleepiness, and looked for any safety issues.

This study looked at whether getting treatment for obstructive sleep apnea (OSA) sooner helps people use their breathing machine (PAP) more consistently. Over 100 adults with OSA were randomly assigned to either early or usual care. The goal was to see if faster care leads to bet…

This study tested how easy it is to use a new CPAP mask (the Eclipse) compared to a traditional mask. 35 adults with sleep apnea tried both masks three times each. Researchers measured setup time, technical issues, and how often help was needed. The goal was to see if the new des…

This study tested whether the medication acetazolamide can improve sleep-disordered breathing (sleep apnea) in adults with chronic pain who use opioids daily. 39 participants took either acetazolamide or a placebo for one week. The goal was to see if the drug could reduce breathi…

This small study tested whether a mandibular advancement device (MAD) — a mouthpiece that moves the jaw forward — can reduce how often people with obstructive sleep apnea wake up to urinate at night. Eleven adults with sleep apnea and at least two nightly bathroom trips took part…

This study tested a new automatic feature on a breathing machine (ventilator) to see if it could better manage airway blockages during sleep. 23 adults with conditions like sleep apnea, COPD, or obesity-related breathing problems took part. The goal was to see if the automatic se…

This study tested a new nasal pillows mask (F&P Toffee) for people with obstructive sleep apnea. Forty adults who already used a similar mask tried it at home for 14 days. Researchers measured how well the mask worked by checking sleep apnea events and daytime sleepiness. The goa…

This study tested a device that shines a special light on the throat to treat obstructive sleep apnea. 35 adults with sleep apnea received six 12-minute light treatments over three weeks. Researchers measured if the number of breathing pauses during sleep decreased and if throat …

This study tested whether solriamfetol, a medication for excessive daytime sleepiness, can also improve cognitive function (like memory and attention) in adults with obstructive sleep apnea who still feel sleepy and have trouble thinking clearly. 59 participants took either the d…

This study looked at whether a jaw-widening surgery (surgically assisted maxillary expansion) improves quality of life in adults with obstructive sleep apnea. Nine adults completed surveys about their sleep and daily life before surgery and again 3 months and 1 year after. The go…

This study tested whether doing special tongue and throat exercises after surgery helps people with moderate-to-severe sleep apnea breathe better at night. 51 adults were split into two groups: one did 12 weeks of exercises after surgery, the other had surgery alone. The exercise…

This study tested two different doses of acetazolamide, a drug that helps control breathing, in 91 adults with moderate to severe obstructive sleep apnea. The goal was to see which dose works best to reduce breathing pauses during sleep. Participants took the drug or a placebo fo…

This study looked at ways to help stroke survivors with sleep apnea use their CPAP machine regularly during rehab. About 36 people took part. The goal was to see if simple support could improve nightly use and possibly aid recovery.

This study observed 132 children with obstructive sleep apnea who had their tonsils and adenoids removed. The goal was to see how often breathing complications happen after surgery, especially in children with other health issues. Researchers hope to create better monitoring guid…

This study tested a home-based lifestyle program for people with severe sleep apnea and obesity. 17 adults used remote monitoring devices and received health coaching to improve their health and quality of life. The main goal was to see if the system was easy to use and helpful, …

This study followed 202 children with sleep apnea for 18 years to see how the condition changes over time and what factors affect heart and brain health. Participants completed sleep tests, blood pressure monitoring, heart scans, and thinking assessments. The goal is to understan…

This study looked at how sleep apnea and other health problems like diabetes and high blood pressure affect pain after root canal treatment. Researchers compared pain levels in 78 adults with sleep apnea, with systemic diseases, or who were healthy. The goal was to see if sleep q…

This study tested how well PAP machines, masks, and tubing work for sleep apnea. Thirty ResMed employees used the devices and rated them on a scale of 0 to 10. The goal was to gather feedback to improve future products, not to treat or cure the condition.

This study looked at how specific tongue muscles help keep the airway open during sleep in people with obstructive sleep apnea. Researchers measured airway pressure and collapsibility in 133 participants during a sleep endoscopy procedure. The goal was to better understand the me…

This study looked at 395 adults with obstructive sleep apnea to see if a new tool called the Baveno classification matches the results of the standard overnight sleep test (polysomnography). The Baveno system uses symptoms and health conditions to guide treatment, while the sleep…

This study looked at how surgery might affect the brain in people with moderate-to-severe sleep apnea. Researchers used brain scans and memory tests before surgery, two days after, and six months later. They also checked for signs of confusion after surgery and measured inflammat…

This study tested whether a high-resolution pressure-sensing tube (manometry) can accurately locate where the airway gets blocked during sleep in people with obstructive sleep apnea. Researchers compared it to the standard method, drug-induced sleep endoscopy, in 18 adults and ch…

This study looked at 48 adults with obstructive sleep apnea to see if those with low oxygen levels have more insulin resistance in the liver and fat tissue. Researchers measured fat production and liver fat using special scans and tests. The goal was to understand why sleep apnea…

This study looked at 77 never-smokers newly diagnosed with lung cancer to see how many also have sleep apnea and whether sleep apnea affects their cancer outlook. Participants had a sleep test before starting cancer treatment. The goal is to understand if sleep apnea is linked to…

This study aims to understand why obesity leads to obstructive sleep apnea in some people but not others. Researchers will measure airway collapse and muscle responses during sleep in 106 adults with obesity, both with and without sleep apnea. Participants will be studied before …

This study looked at 178 children who had their tonsils removed to treat sleep apnea. After surgery, they wore a special monitor to track oxygen levels. The goal was to find out how often oxygen drops happen after children go home from the hospital.

This study looked at whether obstructive sleep apnea (OSA) might help cause Alzheimer's disease. Researchers studied 182 older adults aged 65-85, some with and some without sleep apnea, using brain scans and breathing tests. The goal was to understand how sleep disruptions from a…