Mental health

This study tested a chatbot called ParentText for Crisis, designed to support Palestinian caregivers living in a refugee camp in Jordan. The goal was to see if the chatbot could improve caregivers' mental health, encourage positive parenting, and reduce violence against children.…

This trial explores whether digital tools designed for Asian American clients, along with special training for therapists, can help reduce stress, perfectionism, and symptoms of depression and anxiety. About 80 Asian American adults seeking mental health care will be involved, al…

This trial tests a program called Kupambana for young people with HIV in Zambia. It combines weekly peer-led support groups to reduce stigma with a voucher for vocational training and a financial literacy session. Researchers want to see if this approach can improve mental health…

This study compares two weight-loss strategies: GLP-1 medications (like semaglutide or tirzepatide) versus a structured diet and exercise program. Adults with a BMI of 27.5 or higher are followed for three months to see which approach better improves heart and metabolic markers, …

This trial tests whether a 'link work' intervention can help people with severe mental health difficulties attend routine dental appointments. 480 participants will be assigned to either the link worker support plus usual care, or usual care alone. The study measures whether they…

This trial tests a 12-week home-based digital cardiac rehabilitation program for people with coronary artery disease. It aims to improve heart health, reduce hospital visits, and enhance quality of life, especially for older adults, women, and those with other health issues. The …

This study tests a talk therapy called CETA for 300 mothers in a low-income area of Lima, Peru. The therapy aims to reduce depression, anxiety, and stress, and improve parenting and children's well-being. Another 300 mothers receive standard support. Researchers will follow famil…

This study tests whether a program called SBIRT (Screening, Brief Intervention, and Referral to Treatment) can help people reduce risky alcohol and drug use. About 400 adults visiting family planning clinics will either get SBIRT or usual care. Researchers will track changes in d…

This trial tests a program called WeCare, which combines problem-solving therapy with support for taking HIV medication. It is designed for men who have sex with men (MSM) in South Africa. The study will enroll 60 participants to see if the program reduces depression and anxiety,…

This study tests whether taking a daily multivitamin and multimineral supplement for 12 months can improve metabolic, mental, and muscle health in women aged 40-60. Researchers will measure changes in a biomarker called MetaboAge, which reflects overall metabolic health. The tria…

This study tests whether a trauma-focused group therapy (CPT-CJ) given in prison can reduce drug use, PTSD symptoms, and re-arrest after release. 640 incarcerated adults from about 10 prisons will either receive the group therapy or a self-help workbook. Researchers will also mea…

Researchers are testing whether a program called Feel Good, which uses ten playful classroom sessions, can help children in grades 4 and 5 build life skills like empathy and self-awareness. The goal is to see if these skills improve the school climate and children's well-being. A…

This trial tests a school-based program called the Young Athlete Body Project, designed for adolescent athletes in Norway. The program includes digital lessons and group workshops that challenge unhealthy appearance ideals and build resistance to social pressures. Researchers wil…

This study tests a digital tool called the Family Check-Up Online, designed to prevent family violence and improve child mental health. About 1,270 families with children aged 11-14 will use the program, with some getting extra coach support. Researchers will measure changes in p…

This study tests a program designed to improve well-being and prevent mental health issues in children aged 8-10 and their parents. Over 15,000 families in four European countries will take part. Children attend a mental health day at school, while parents receive either training…

This study tests a digital escape room game designed to teach high school students about the risks of gambling. Researchers will compare gambling habits and attitudes between students who play the game and those who don't. The goal is to see if this fun, interactive approach can …

This study tests a two-level train-the-trainer model to scale up a mental health program for teachers in Ugandan schools. The program, called mWEL-PD, trains teachers to support their own wellbeing and that of their students. Researchers will compare this new model with and witho…

This study tests a risk calculator and online parenting program for toddlers at risk of mental health challenges. Caregivers of 432 toddlers will use the Family Check-Up® Online program, which offers tools and coaching to support emotional and behavioral development. The goal is …

This study tests a culturally adapted version of the Strong Families programme in Gilgit Baltistan, Pakistan. The programme teaches parenting skills and strengthens family bonds to prevent drug use, violence, and other problems in children aged 8-15. About 90 families will be ran…

This study tests a 9-month program called NE+ for American Indian youth aged 12-18. The program includes educational modules and cultural teachings to encourage abstinence, condom use, and avoid substance use. It also involves parents and school staff. The goal is to see if the p…

This study tests a program called Shamba Maisha that provides farming tools, training, and school gardens to families in Kenya. The goal is to reduce food insecurity and poverty, which are linked to higher STI and HIV risk in adolescent girls. Researchers will follow 900 girls an…

This trial tests whether a four-week improv comedy program can reduce anxiety and improve mental well-being in Chinese young adults in Hong Kong who have mild-to-moderate anxiety but no diagnosed mental disorder. Participants attend weekly three-hour improv workshops and complete…

This study tests whether a generative AI chatbot can help new mothers learn about pelvic floor health and reduce feelings of loneliness after childbirth. Researchers will compare standard postpartum care with or without access to the chatbot over 4 weeks. The trial involves 130 f…

This study tests a text message program for new parents in Nova Scotia. 332 first-time parents will either receive daily texts for 6 weeks with tips on baby care and mental health, or no texts. Researchers will compare confidence, anxiety, depression, and co-parenting between the…

This study looks at whether a 6-month dance exercise program can improve physical performance, metabolic health (like blood sugar and cholesterol), and mental health in women before and after menopause. Forty women will either take part in supervised dance sessions twice a week o…

This study tests whether a structured emotional intelligence (EI) training program can improve mental health and reduce anxiety and depression among secondary school teachers and students in Dhaka, Bangladesh. The program teaches skills like self-awareness, self-management, socia…

This study tests a programme called Mentis Plus+ Caregivers, designed to improve mental health for adults who care for a family member with dementia. The programme includes six modules that teach skills like self-control, problem-solving, and building relationships. Researchers w…

This study looks at whether giving parents of children with chronic conditions a mental health questionnaire during clinic visits is practical and helpful. About 100 parents will fill out the survey and receive a list of support services. Researchers will follow up at 3 and 6 mon…

This study tests whether an 8-week virtual Mindfulness-Based Stress Reduction (MBSR) program can reduce fatigue, anxiety, and depression in 100 adults with sarcoidosis. One group takes MBSR; the other joins a monthly virtual support group. Researchers will compare which approach …

This study looks at whether a 16-week program combining mindfulness meditation and Nordic walking pole exercise can improve physical function, mood, and sleep in adults aged 55 and older. About 1,500 participants will take part in the program and be assessed at several points. Th…

This study tests a virtual health coaching program for adults with type 2 diabetes who also face mental health challenges like anxiety or diabetes distress. Participants receive weekly coaching calls, support from a care team, and online tools to help manage both conditions. The …

This study tests an AI chatbot called Aurora that guides people through creating a personal life story to improve emotional well-being and identity. It includes healthy adults, adults with mental health conditions in residential care, and older adults aged 65+. The chatbot is not…

This study tests an online self-help platform called JCTH+ for university students in Hong Kong who have moderate to severe anxiety or depression. About 1,684 students will either use the platform plus usual services or just usual services. The goal is to see if the platform impr…

This study looks at whether intermittent fasting (the 16/8 method, where you eat only during an 8-hour window each day) can improve mental health in women going through perimenopause. About 140 women aged 45-55 will be split into two groups: one that follows the fasting plan and …

This study tests whether an 8-week mindfulness course can improve mental well-being and teaching skills in 160 Chinese teachers. Participants will learn mindfulness techniques and researchers will measure changes in stress, anxiety, and classroom effectiveness. The goal is to see…

This study tests whether regular, caring phone calls from trained volunteers can reduce loneliness, depression, and thoughts of suicide in older adults who are homebound and receive community services. About 400 people aged 65 and older will be assigned to one of two types of pho…

This study tests whether a short course of cognitive behavioral therapy (CBT) can reduce anxiety and pain in teenagers recovering from scoliosis surgery. About 45 teens aged 10–19 will receive either standard care or CBT sessions (plus a mobile app) before and after their operati…

This study tests whether a culturally adapted skills training program called START NOW can reduce depression and anxiety in teen refugees. About 80 participants aged 14-18 will be randomly assigned to either the training or standard care. The goal is to see if the program helps t…

This study tests a free mobile app called Stappvoorstap for adults on mental health waiting lists in the Netherlands. The app tracks daily stress, offers coping tips, relaxation exercises, and educational content. Over 4 weeks, 54 participants will use the app and complete questi…

This study looks at whether an 8-week mindfulness program can help university basketball players improve their skills, body control, and mental well-being. About 126 athletes will be split into a mindfulness group, a psychological skills group, or a standard control group. They w…

This study tests whether a 12-week digital MediYoga program—combining deep breathing, gentle yoga, and meditation—can improve quality of life, lower blood pressure, and reduce heart rate in 456 adults with paroxysmal atrial fibrillation. Participants use a smartphone app and get …

This study looks at whether eating nuts can help reduce symptoms of depression, anxiety, and stress, and improve memory and thinking skills in young adults. Researchers will enroll 135 university students aged 18 to 25 and measure changes in mood, cognitive function, and a brain-…

This study tests a program called Mental Health CPR, designed to help Hispanic/Latino cancer survivors in Puerto Rico improve their emotional well-being and connect with mental health services. About 1,260 participants will attend community sessions led by trained workers, compar…

This study tests whether a contemplative practice called Feeding Your Demons (FYD), adapted from Tibetan Buddhism, can improve psychological well-being, body image, and self-compassion in women aged 30-60. Participants will be randomly assigned to either FYD or a standard mindful…

Researchers are building a long-term health study of 150,000 children born in Victoria, Australia, and their parents. The study follows participants from birth over their lifetime, collecting data on health, development, and environment through surveys, biosamples, and linked rec…

This study uses online surveys to explore whether cancer patients and their family members across the European Union have equal access to mental health screening and psychological support. Researchers will analyze responses from 2,000 participants to identify disparities, barrier…

Researchers are enrolling thousands of French college students to track how symptoms of anxiety, depression, ADHD, sleep problems, and other factors interact over time. Instead of counting how common these issues are, the study uses a network approach to see how symptoms influenc…

This study aims to adapt and validate a French version of the Recovery Assessment Scale (RAS), a questionnaire that measures how people feel about their own recovery from mental health conditions. Researchers will ask 260 adult psychiatric patients in France to fill out the RAS a…

This study looks at whether doulas with extra training in mental health support can help pregnant women in rural Montana feel more confident and less depressed. About 75 pregnant women will be split into three groups: one with a specially trained doula, one with a regular doula, …

This study tests whether adding 8 weeks of mindfulness training to a single dose of psilocybin (the active ingredient in magic mushrooms) improves mental health more than psilocybin alone. Forty healthy adults who have never used psychedelics or done formal mindfulness training w…

This study looks at how the recent war in Israel has impacted children and teens, and what factors influence the success of psychotherapy. Researchers will analyze data from 30,000 participants to understand why many kids drop out of therapy and what can be done to improve outcom…

This study investigates whether restricting access to social media apps on smartphones for three months can improve anxiety and depression in adolescents aged 10 to 14. Half of the 500 participants will have no social media apps on their phones, while the other half will use them…

This study follows up with people who survived a dangerous heart condition called electrical storm and were treated in the ICU. Researchers want to understand how the experience and treatments affect mental health and quality of life. Participants fill out questionnaires about PT…

This study is testing a web-based tool called ORCA-A that helps state decision-makers choose the best evidence-based programs to support parent and child mental health. Researchers will work with 80 adults involved in state-level decisions under the Family First Prevention Servic…

This study tests whether 'Hope Groups'—a 10-session support program for parents and caregivers—can reduce violence against children and improve mental health among Palestinian families displaced by war. About 490 caregivers living in refugee camps will take part. The program comb…

This study is developing and testing a program called THRiVE for veterans who recently left the military. The program consists of six weekly virtual group sessions led by a peer (another veteran). The goal is to see if the program is practical, well-liked, and may help improve me…

This study follows 300 young men who have sex with men (ages 18-24) living with HIV in Ho Chi Minh City, Vietnam, for 12 months. Researchers will track how well they stick to their HIV medication, their viral suppression, mental health, and quality of life. The goal is to underst…

This study aims to understand the long-term mental, physical, and social impacts of COVID-19 on minority women and their families in North Carolina. About 700 healthy women aged 18 and older who are African American, Hispanic, Native American, Asian American, or Pacific Islander …

This study compares two support programs for Black men who have been in jail or prison and are at risk for or living with HIV. One group gets health navigation only; the other also gets employment help and up to $340 in incentives. Researchers want to see which approach better co…

This study tests an online program called eBASIS designed to help school mental health providers feel more confident and motivated to use evidence-based practices. Researchers will compare providers who use eBASIS to those who don't, measuring changes in their attitudes and skill…

This study tests whether adding a tool called the Pleasuremeter to standard harm reduction services helps men who have sex with men and transgender people who use drugs or engage in chemsex talk about and improve their sexual pleasure. The goal is to see if people are willing to …

This study is gathering information from men who have sex with men who take part in chemsex (using drugs before or during sex) in Bangkok, Thailand. Researchers will survey party hosts and guests about their drug use, sexual health, mental health, and experiences of stigma. The g…

This study tests a digital dashboard tool to help community workers deliver a family-based mental health program called Sugira Muryango in Rwanda. The goal is to see if the technology improves how well the program is delivered, including fidelity and worker confidence. Over 1,800…

This study tests a system called PRPP that helps occupational therapists understand how cognitive problems affect daily tasks in older adults with psychiatric disorders. Researchers want to see if using this system leads to better decisions about keeping people safe at home inste…

This observational study seeks to define a new concept called 'visual frailty' in people aged 60 and older with advanced age-related macular degeneration (AMD). Researchers will measure vision, reading ability, mental health, and daily function in 20 participants to develop a vis…

This study partners with community organizations to improve participation in health research among Black, Latino, and Native American communities in Colorado. Researchers will track changes in diet, transportation access, and social support over time. The goal is to build lasting…

This study tests a program called FRAME that helps heart failure patients discuss stress, anxiety, and depression with their doctors and loved ones. About 7,300 patients in Ontario, Canada will take surveys before and after using the tool. The goal is to see if the program makes …

This study tests whether a 10-session parenting program called Attachment and Biobehavioral Catch-up (ABC) can reduce stress-related biomarkers in children aged 2 to 3.5 years who have experienced early adversity. About 150 caregiver-child pairs will be randomly assigned to recei…

This study tests a program called Level Up, which teaches life skills like stress management and healthy relationships to soldiers at their first duty station. 5,000 soldiers will be randomly assigned to either Level Up or a standard bystander training. Researchers will track har…

This study tests whether a website called SolanoConnex.org helps people with mild to moderate mental health symptoms take steps to get support. About 200 adults in Solano County, California, will be randomly assigned to use the website or receive standard resources. Researchers w…

This study explores whether a combination of EEG neurofeedback (Monroe) and a digital tool (Neuphoria) can improve mental clarity and well-being. Researchers will measure brain activity and stress levels in 100 adults. The goal is to understand how these tools affect the mind, no…

This study tests whether a choice-driven, interactive storytelling web app can help Latinas with anxiety or depression start mental health treatment. Seven hundred participants in Los Angeles and Orange County will either use the story-based app or a control webpage with standard…

This study tests whether teaching married couples about money management and healthy relationships can strengthen their bond and improve their mental health. About 4,500 couples in rural and urban India will take part. The program involves six sessions and aims to reduce stress a…

This study looks at how myelin, the insulation around nerve fibers, influences thinking and problem-solving in people aged 10 to 25. Researchers will use MRI scans and cognitive tests to measure brain structure and mental skills. The goal is to better understand normal brain deve…