MENTAL HEALTH

This study tests a program called Project YES+ for youth aged 15-21 living with HIV in Zambia. It combines peer mentoring with a mental health approach to reduce stigma from HIV, violence, and mental health issues. The goal is to help them stick with their HIV treatment and impro…

This study tests whether a trauma-focused group therapy (CPT-CJ) given in prison can reduce drug use, PTSD symptoms, and re-arrest after release. About 640 incarcerated adults from 10 prisons will either receive the group therapy or a self-help workbook. Researchers will also mea…

This study tests two types of support for Black men who have been in jail or prison and are at risk for or living with HIV. One group gets health navigation, and the other gets extra help finding a job and money for health and career goals. The goal is to see which approach helps…

This study tests whether taking a daily multivitamin for 12 months can improve metabolic, mental, and muscle health in midlife Asian women aged 40-60. Researchers will measure changes in a blood-based 'MetaboAge' score and other health markers. The goal is to find a simple way to…

This study tests an online program called Family Check-Up Online, designed to help parents improve their parenting skills and reduce family conflict. About 1,270 families with children aged 11 to 14 will take part. Some families get the program with a coach, others without. The g…

This study aims to prevent mental health problems by training teachers to support students' mental wellbeing and manage their own stress. About 1,556 participants, including teachers and school staff, will test a new two-level training model that uses digital learning to reach mo…

This study tests a program called Shamba Maisha that provides farming tools and training to households in Kenya. The goal is to see if reducing food insecurity and poverty can lower the risk of sexually transmitted infections (STIs) and HIV in 800 teenage girls aged 15-19. Partic…

This study looks at gambling habits in 16- to 25-year-olds in Spain after COVID-19 and tests a digital escape room game designed to prevent gambling in high school students. About 240 students aged 16-18 will take part. The goal is to see if the game increases knowledge and reduc…

This study tests a 9-month program called NE+ for American Indian youth ages 12-18. The program includes educational modules, cultural teachings, and caregiver involvement to promote healthy relationships, prevent substance use, and improve mental health. Researchers will compare…

This study looks at whether intermittent fasting (the 16/8 method, where you eat only during an 8-hour window each day) can help improve the mental health of women going through perimenopause. Researchers will split 140 women aged 45-55 into two groups: one that follows the fasti…

This study tests whether a 12-week digital MediYoga program—combining deep breathing, gentle yoga, and meditation—can improve quality of life, blood pressure, and heart rate in 456 adults with paroxysmal atrial fibrillation. Participants use a smartphone app and get online suppor…

This study tests a program called Mentis Plus+ designed to improve positive mental health in adults who care for a family member with dementia. About 108 caregivers will either join the program or continue with usual care. The goal is to see if the program helps caregivers feel b…

This study looks at whether a 16-week program combining mindfulness meditation and Nordic walking-pole exercise can improve physical function, mood, and sleep in adults aged 55 and older. About 1,500 participants will take part from community settings. The goal is to see if this …

This study tests whether an 8-week virtual Mindfulness-Based Stress Reduction (MBSR) program can reduce fatigue in people with sarcoidosis. It also looks at effects on anxiety and depression. About 100 adults with sarcoidosis and fatigue will either join the MBSR program or a mon…

This study tests whether an 8-week mindfulness course can improve teachers' mental health and teaching skills. 160 teachers will participate and report on stress, anxiety, and classroom effectiveness. The goal is to see if mindfulness practice leads to real benefits in schools.

This study tests a program called Mental Health CPR, designed to help Hispanic/Latino cancer survivors in Puerto Rico feel better emotionally and connect with mental health services. About 1,260 adults will take part in community sessions led by trained workers. The goal is to se…

This study tests a structured psychological program for teenagers (ages 10-19) with scoliosis who are having spine surgery. The program uses cognitive behavioral therapy techniques to help manage anxiety and pain before and after the operation. Researchers will measure changes in…

This study tests whether a 6-week text message program can help new parents feel more confident and less anxious or depressed after their first baby. About 332 parents in Nova Scotia will either receive the texts or not, and researchers will compare their confidence, anxiety, and…

This study tests whether an online self-help platform called JCTH+, combined with existing support services, can reduce anxiety and depression symptoms in university students. About 1,684 students in Hong Kong with moderate to severe symptoms will be randomly assigned to use the …

This study compares a 3-session couple-based program (Brief Relationship Checkup) to standard individual care for 360 veterans and their partners who have relationship and mental health concerns. The goal is to see which approach better reduces suicide risk factors by improving r…

This study tests a virtual health coaching program for 160 adults with type 2 diabetes and mental health struggles. Participants get weekly coaching calls, support from a care team, and online tools. The goal is to see if this approach improves quality of life and reduces diabete…

This study looks at whether adding nuts to the diet can improve mental health in young adults. Researchers will measure changes in depression, anxiety, stress, memory, and thinking skills in 135 university students aged 18 to 25. Participants will eat nuts or follow their usual d…

This study tests a chatbot that guides people through telling their life story to improve emotional well-being. It includes healthy adults, people with mental health conditions in residential care, and older adults aged 65+. The chatbot is not a treatment but a tool to support em…

This study looks at whether an 8-week mindfulness program can help university basketball players improve their skills, body control, and mental well-being. About 126 athletes will be split into three groups: one does mindfulness, another does standard mental skills training, and …

This study tests whether regular, friendly phone calls can improve mental health and reduce loneliness in older adults who are homebound. About 400 people aged 65 and older will receive either supportive calls from trained helpers or no calls during the study. The goal is to see …

This study tests whether a culturally adapted skills training program called START NOW can reduce depression and anxiety in teenage refugees. About 80 participants aged 14 to 18 will be randomly assigned to either the START NOW program or standard care. Researchers will compare c…

This study tests whether adding a special supplement to a mindfulness program helps college students aged 18-25 feel less stressed, anxious, or depressed. About 120 students with high stress will join one of three groups: mindfulness only, mindfulness plus supplement, or a health…

This study tests whether adding 8 weeks of mindfulness training to a single dose of psilocybin (the active ingredient in magic mushrooms) improves mental health more than psilocybin alone. Forty healthy adults aged 25+ who have never used psychedelics or done formal mindfulness t…

This study tests a mobile app called Stappvoorstap for adults on mental health waiting lists in the Netherlands. Over 4 weeks, participants use the app to track stress, learn coping skills, and access relaxation exercises. The goal is to see if the app can reduce stress and impro…

This study tests a contemplative practice called Feeding Your Demons (FYD), adapted from Tibetan Buddhism, to see if it helps women feel better mentally and about their bodies. About 122 adult women who already meditate will be randomly assigned to FYD or standard mindfulness med…

This study follows 300 young men who have sex with men (ages 18-24) living with HIV in Ho Chi Minh City, Vietnam, for 12 months. Researchers will track how well they stick to their HIV medication, their viral suppression, and their mental health. The goal is to learn what helps o…

This study tests a program called FRAME that helps heart failure patients talk about mental health with their doctors and family. About 7,300 adults with heart failure or at risk for it will take part. The goal is to see if the program makes it easier for patients to get mental h…

This study tests an online program called eBASIS that helps school mental health providers stick to proven therapy methods. About 32 providers and 96 students will take part. The goal is to see if eBASIS improves how well providers use the therapy and how students benefit.

This study looks at whether doulas who receive extra training in supporting mental health (called PMADs) can help pregnant women in rural Montana feel more confident, supported, and less depressed or anxious. About 75 pregnant women will be split into three groups: one with a reg…

This study compares two web-based apps to see which one better helps Latinas with anxiety or depression start mental health treatment. One app uses an interactive story with a character who gives treatment advice, while the other provides standard information and resources. The g…

This study tests a mobile app called Level Up that teaches life skills to soldiers arriving at their first duty location. The goal is to see if it reduces harmful behaviors like suicide attempts, improves mental health, and helps soldiers perform better at work. About 5,000 soldi…

This research study looks at how myelin, the insulation around brain nerves, influences thinking skills in people aged 10 to 25. Participants will have an MRI scan and complete thinking tasks. The goal is to understand brain development, not to test a treatment.

This study tests a program for parents of children with disabilities who are about to start special education. The program includes six learning sessions to help parents work as a team, access services, and support their child. Researchers will compare parents who take the progra…

This study looks at what 'visual frailty' means for people aged 60 and older who have age-related macular degeneration (AMD). Researchers will measure vision, reading ability, daily function, mental health, and other health conditions to create a new assessment tool. The goal is …

This study is developing and testing a web-based decision-support tool to help state leaders choose the best evidence-based programs for improving parent and child mental health. About 80 adult decision-makers involved in state child welfare policy will use the tool and provide f…

This study tests whether a 10-session parenting program called Attachment and Biobehavioral Catch-up (ABC) can reduce stress-related biomarkers in children aged 2 to 3 who have experienced early life challenges. About 150 caregiver-child pairs will be randomly assigned to receive…

This study aims to understand how the COVID-19 pandemic has affected the mental, physical, and social well-being of minority women and their families in North Carolina. Researchers will survey 700 healthy women aged 18 and older from African American, Hispanic, Native American, A…

This study looks at whether giving parents of children with chronic conditions a mental health questionnaire during clinic visits can help spot stress, anxiety, or depression. About 100 parents will fill out the survey, get their results and a list of support services, and be che…

This study follows up with people who survived a life-threatening heart rhythm problem called electrical storm and were treated in the ICU. Researchers want to learn how these patients are doing mentally and emotionally 3 to 6 months later. Participants fill out short questionnai…

This study looks at whether a training program that teaches emotional intelligence can help secondary school teachers and students in Dhaka feel less anxious and depressed and improve their overall well-being. About 80 participants will be split into two groups: one gets the trai…

This study looks at whether adding conversations about sexual pleasure to existing harm reduction services helps men and transgender people who use drugs in Thailand. Researchers will use a tool called the Pleasuremeter to measure sexual satisfaction and willingness to discuss pl…

This study tests whether a website called SolanoConnex.org helps people with mild to moderate mental health symptoms take steps to get support. About 200 adults in Solano County, California, will be randomly assigned to use the website or receive standard public resources. Resear…

This study is developing and testing a small-group program called THRiVE for veterans who left the military within the last year. The program is led by peers and focuses on improving mental health and reducing suicide risk. Up to 40 veterans will try the program and report on the…

This study looks at whether a tool called PRPP (Perceive, Recall, Plan and Perform) can help doctors and therapists decide the best way to support older adults with psychiatric disorders who live on their own. The tool measures how well a person can perform everyday tasks and how…

This study tests whether a program that teaches married couples about money and healthy relationships can improve their bond and mental health. About 4,500 couples in three Indian states will take part. The program involves six sessions, and researchers will measure changes in re…

This study aims to improve health research participation among Black, Latino, and Native American communities in Colorado. Researchers will work with local organizations to address health issues like mental health, high blood pressure, and diabetes. About 1,500 adults aged 18-90 …

This study talks to men who have sex with men and take part in chemsex (using drugs during sex) in Bangkok. Researchers want to understand the physical, mental, and social harms they face. The goal is to design a program led by hosts of chemsex parties to reduce risks like HIV, S…

This study is testing whether 'Hope Groups' — a program that offers mental health support, parenting help, and violence prevention — can improve the well-being of Palestinian caregivers displaced by war. About 490 participants from refugee camps will take part. The goal is to see…

This study tests whether a device called Neuphoria, used with Monroe's EEG neurofeedback, can improve mental clarity and well-being. Researchers will measure brain activity, stress levels, and mindfulness in 100 adults. The goal is to understand how the brain responds to this tra…

This study tests a training program called First Face for Mental Health in seven Tribal Nations. About 1,000 community members aged 14 and older will take part. Half get the training right away, the other half wait six months. Researchers will compare surveys to see if the traini…

This study tests whether a digital dashboard can help home visitors in Rwanda deliver mental health support more effectively. The program, called Sugira Muryango, aims to improve family well-being and reduce violence. About 1,800 caregivers and officials will take part to see if …

This study aims to understand how the recent war in Israel has impacted the mental and physical health of children and adolescents, and what makes their therapy successful or leads to dropping out. Researchers will analyze data from 30,000 young people in therapy, looking at fact…