Mental health

This study tests whether connecting families with financial coaching and social services during pregnancy or right after birth can improve parent mental health, pregnancy outcomes, and child development. Around 1,200 English- or Spanish-speaking expectant parents will be randomly…

This trial tests a culturally adapted program called Health Without Barriers/Salud Sin Barreras for teens aged 11–19 and their families in Northern Colorado. The program combines mindfulness, nutrition education, physical activity, and parenting support over several sessions. Res…

This study tests a 12-week home-based digital program called eCardiacRehab for people who have had a heart procedure (PCI). The program includes video messages, modules, and tracking to support recovery. Researchers want to see if patients will use it regularly and find it accept…

This trial tests a school-based program called HENKA, designed to promote emotional well-being and prevent mental health problems in adolescents aged 12 to 16. The program includes eight classroom sessions on skills like self-esteem, emotional regulation, and mindfulness, taught …

Researchers are testing whether ParentText, a WhatsApp-based parenting programme, can be delivered through government health services in South Africa's Western Cape. The programme has two five-lesson modules: one on improving caregiver-child relationships and one on keeping child…

This study tests two counseling programs to help women who use drugs in Tanzania start and stay on PrEP, an HIV prevention pill. 200 women will be randomly assigned to receive either brief motivational counseling, the same plus extra mental health support, or standard information…

This study tests a program called BasketballRx, which combines basketball activities with lessons on healthy eating, exercise, sleep, and stress management. The program is designed for teens aged 10 to 15 who are overweight or have obesity, and who identify as Black or Latino. Ov…

This study tests a smartphone app designed to help women ages 18–59 in the U.S. drink less alcohol and feel better mentally. The app uses weekly quizzes, a social feed, and helpful articles to give personalized feedback. Researchers will track drinking habits and mental health ov…

Researchers at Cambridge Health Alliance are adapting a mental health screening and support program for racially, ethnically, and linguistically diverse youth aged 12 to 17 in the Denver Health area. The program includes screening, feedback, a single session intervention, and res…

This pilot study tests whether a 4-week virtual mindfulness-based group intervention with social support is feasible and acceptable for pregnant individuals at higher risk for substance use. Participants join weekly video conference groups focused on grounding, thinking patterns,…

This study compares a 3-session couples program (Brief Relationship Checkup) to standard individual care for 360 veterans and their partners who have relationship and mental health concerns. The goal is to see which approach better reduces suicide risk factors by improving relati…

This study tests whether an 8-week online Mindfulness-Based Stress Reduction (MBSR) program can help healthcare professionals recover from work-related stress and reduce burnout. Participants who provide direct patient care will either join the online program or be placed on a wa…

This pilot study tests a 13-week Dialectical Behavioural Therapy (DBT) skills training program for Canadians who have recently started or will soon start facility-based hemodialysis. The goal is to see if the program is feasible and helpful for improving mental health and reducin…

This study tests whether a noninvasive technique called repetitive transcranial magnetic stimulation (rTMS) can reduce irritability by targeting brain circuits involved in frustration. About 20 adults with elevated irritability will receive rTMS while researchers measure brain ac…

This pilot study tests a WeChat-based program that provides daily mental health check-ins and tailored coping strategies for people with ankylosing spondylitis who also have mild-to-moderate depression or anxiety. Thirty-six adults will be split into two groups: one receives the …

This study tests whether a smartphone app that teaches mindfulness and sends personalized messages can reduce depression and anxiety in people waiting for in-clinic mental health services. About 4,400 adults seeking care at Michigan Medicine will use the app and report their symp…

This study looks at whether adding a special supplement to a mindfulness program can help college students feel less stressed, anxious, or depressed. About 120 students aged 18-25 with high stress levels will take part. They will be split into groups: one gets mindfulness trainin…

This study planned to test whether taking a prebiotic supplement for six weeks could reduce morning cortisol levels in healthy young adults aged 18-25 with mild to moderate stress. Participants would have provided saliva, stool, urine, and blood samples. However, the trial was wi…

This study tests whether a mobile app that offers self-help tools and an AI chatbot can improve mental health for women in Mexico. 4000 women with mild to moderate distress will use the app. Researchers will measure changes in well-being, anxiety, depression, and stress.

This study tests whether listening to specific sound frequencies for just 9 minutes a week can improve mental health. 110 adults with mild anxiety, stress, or depression will either sit in a special sound chamber or use headphones. The goal is to see if this simple, drug-free app…

This study tests whether watching 10-minute 360° nature videos twice a week for 12 weeks can improve quality of life, mood, and agitation in nursing home residents with dementia. Sixty residents will be randomly assigned to either the virtual nature program or their usual care. R…

This study tests whether adding a doula to standard pregnancy care can improve mental health and birth outcomes for Black birthing people. 230 participants will be randomly assigned to receive doula support or standard care alone. The main goal is to see if doula care lowers depr…

This study tests a web-based toolkit designed to improve psychological immunity, self-care, and job performance among early childhood development (ECD) frontliners in Lebanon. Fifty teachers, social workers, and caretakers who work with children under 8 will use the toolkit and r…

This study tests a program called Meet Me on the Pitch (MMotP) that combines soccer with behavioral health sessions for teens aged 14-21. The goal is to improve mental health, well-being, and academic support. Researchers will compare the program to standard sports activities in …

This study tests whether trained LGBTIQA+ community members can provide effective counseling to reduce psychological distress and violence exposure. About 960 LGBTIQA+ adults in Nepal will receive either individual counseling, counseling plus group sessions, or standard care. The…

This study looks at whether a group stress management program called Self-Help Plus (SH+) can improve the mental health of refugee mothers and their preschool children in Uganda. About 725 mothers and their children will take part, with some villages getting the program and other…

This study tests whether a mindfulness program can help 58 high school students reduce their addiction to short-form videos like TikTok or Instagram Reels. Teens who score high on a video addiction scale will either join the program or a control group. Researchers will measure ch…

This study looks at whether acupuncture can help people with schizophrenia feel better by reducing side effects from their medication and improving psychiatric symptoms. About 100 participants will receive acupuncture twice a week for four weeks. Researchers will measure anxiety,…

This study tests a 14-day digital writing program designed to help parents of autistic individuals manage stress and improve mental health. Participants use a WeChat mini-program to write about their feelings and practice self-kindness for about 5 minutes each day. The trial incl…

This study tests a group program called RISE for Nurse Preceptors. It aims to reduce burnout and improve resilience, self-compassion, and well-being in nurses who train new staff. About 124 nurse preceptors from one hospital system will take part. The program involves group sessi…

This 10-year study follows 1,500 young people aged 10-24 to learn what makes some more resilient to depression and anxiety than others. Researchers will track lifestyle, brain scans, and mental health over time. No treatments or interventions are given—the goal is simply to obser…

This trial tests a home-based intervention called Khanya-Ekhaya, delivered by community health workers, to support the mental health of people living with HIV in South Africa. The intervention combines counseling techniques like motivational interviewing and problem-solving thera…

This study surveys 1,500 former Norwegian elite athletes to map their mental and physical health after retirement. Researchers focus on differences between weight-sensitive sports, such as weight-class, aesthetic, and endurance sports, and less weight-sensitive ones. They will ex…

This study compares two versions of school-based mental health screening to see which helps more African-American elementary students get the mental health services they need. Researchers will track referrals and disciplinary incidents across many schools. The goal is to find bet…

This study tests a new program called M-HARP that helps new mothers get health screenings and referrals during their baby's regular doctor visits. About 150 women in the Dominican Republic will take part. The goal is to see if this approach makes it easier for moms to get postpar…

This study follows about 2,200 mothers and their children in Cox's Bazar, Bangladesh, including Rohingya refugees and local families. Researchers want to understand how growing up in conflict and displacement affects child development and mental health. They are also looking at w…

This study explores whether attending free community events in renovated neighborhood parks can improve sleep, stress, mood, and overall well-being in adults aged 18 and older who live nearby. Participants wear a smart ring to track sleep and complete surveys over about six month…

This study in Sierra Leone tests whether using mobile phones to supervise teachers can improve how they deliver a mental health program called the Youth Readiness Intervention (YRI) to students. About 1,454 youth and their teachers from secondary schools will take part. The YRI i…

This study tests whether a program that teaches married couples financial skills and respectful communication can improve how they parent their children. Over 2,200 couples in three Indian states attend six group sessions together, covering budgeting, saving, and fair household r…

This study adapts an existing stigma-reduction program specifically for pregnant and postpartum women living with HIV in Ghana. Researchers will interview 30 women and 20 providers to understand their experiences, then work with stakeholders to tailor the program. Finally, 90 pre…

This study looks at whether medical-legal partnerships—where lawyers work closely with healthcare providers—can help veterans with housing problems avoid eviction and homelessness better than standard legal services alone. About 300 veterans will be randomly assigned to either th…

This study uses data from over 30,000 Swedish adults to see if using snus (including newer white nicotine pouches) is linked to heart disease, metabolic problems, and poor mental health, independent of smoking. Researchers will compare current, former, and never-users using advan…

This study looks at a program called VOCES-NUEVAS for newcomer girls from Latin America in Oakland schools. The goal is to see if the program fits well in schools and helps improve mental health. About 24 girls will take short surveys before and after the program, and give feedba…

This study tests a new classroom setup where traditional desks are replaced with standing desks, fitballs, and wall boards to get kids moving more. Researchers will track 500 students in Spain to see if this reduces sitting time and improves thinking, fitness, and well-being. The…

This study tests whether a culturally adapted comic series called 'Magnificent Mei & Friends' can improve socio-emotional skills in 10-14 year old students in Rawalpindi, Pakistan. About 120 adolescents from 4 schools will take part, with some schools using the comics and others …

This study planned to use high-frequency brain signals to locate important brain areas and understand conditions like epilepsy, migraine, and ADHD. It aimed to create a large database of brain activity in people aged 1 day to 69 years. However, the study was withdrawn before any …

This study tests a training program for occupational therapists who work with adults who have had a brain injury. The goal is to help therapists better spot and treat anxiety and depression in their patients. Twenty therapists will take part, and researchers will see if they star…

This study is surveying 2500 adults from Croatia, Greece, Italy, Slovenia, and Spain to explore how diet, exercise, sleep, stress, and social habits relate to physical and mental health. Participants complete an online questionnaire about their lifestyle and well-being. The goal …

This study follows 192 teens aged 12 to 20 who are already receiving either Cognitive Behavioral Therapy (CBT) or Brief Strategic Therapy (BST) for anxiety, depression, or OCD. Researchers will track their progress using questionnaires and interviews over 9 months. The goal is to…

This large study will observe up to 300,000 people using a personalized digital physical activity program called Sword Move. Researchers want to see if following this program can improve overall health, quality of life, and mental health. Participants will report changes in anxie…