INFLAMMATORY BOWEL DISEASES
Clinical trials for INFLAMMATORY BOWEL DISEASES explained in plain language.
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Could a cheap cholesterol pill calm ulcerative colitis?
Disease control CompletedThis study tested whether adding atorvastatin (a common cholesterol medicine) to standard treatment can improve quality of life and reduce inflammation in adults with ulcerative colitis. 54 participants completed the trial. Researchers measured changes in bowel and emotional symp…
Matched conditions: INFLAMMATORY BOWEL DISEASES
Phase: PHASE2 • Sponsor: Tanta University • Aim: Disease control
Last updated May 01, 2026 16:01 UTC
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New drug kynteles shows promise for managing IBD in real-world korean study
Disease control CompletedThis study looked at 688 people with ulcerative colitis or Crohn's disease who received Kynteles (vedolizumab) as part of their regular care in South Korea. The main goal was to track side effects, and researchers also measured how many patients saw their symptoms improve. The dr…
Matched conditions: INFLAMMATORY BOWEL DISEASES
Sponsor: Takeda • Aim: Disease control
Last updated May 01, 2026 16:00 UTC
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New pill shows promise for tough UC cases
Disease control CompletedThis study tested an experimental drug called MORF-057 in 39 adults with moderate to severe ulcerative colitis (UC) who had not responded well to other treatments. The goal was to see if the drug could reduce gut inflammation and improve symptoms over 12 weeks. While results may …
Matched conditions: INFLAMMATORY BOWEL DISEASES
Phase: PHASE2 • Sponsor: Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company) • Aim: Disease control
Last updated May 01, 2026 15:59 UTC
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Poop pills show promise for gut disease
Disease control CompletedThis study looked at whether transplanting stool from healthy donors into the gut of people with ulcerative colitis (a type of inflammatory bowel disease) can help control the disease. 102 participants with mild-to-moderate UC received fecal transplants, and researchers measured …
Matched conditions: INFLAMMATORY BOWEL DISEASES
Phase: NA • Sponsor: First Affiliated Hospital of Kunming Medical University • Aim: Disease control
Last updated Apr 29, 2026 15:00 UTC
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Anti-nausea drug may help kids tolerate colonoscopy prep
Symptom relief CompletedThis study tested whether ondansetron, a medicine that prevents nausea and vomiting, could help children and teens (ages 2 to 20) have a better experience with bowel preparation before a colonoscopy. The goal was to see if it improved the quality of the bowel cleanout and reduced…
Matched conditions: INFLAMMATORY BOWEL DISEASES
Phase: PHASE4 • Sponsor: State University of New York - Downstate Medical Center • Aim: Symptom relief
Last updated Apr 30, 2026 15:48 UTC
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Gluten-Free diet tested for ulcerative colitis relief
Symptom relief CompletedThis study looked at whether eating gluten-free can reduce stomach symptoms and tiredness in people with ulcerative colitis. Fifteen adults each spent one week on a gluten-free diet plus a special granola bar, and another week on the same diet but with a high-gluten bar. They rep…
Matched conditions: INFLAMMATORY BOWEL DISEASES
Phase: NA • Sponsor: University of Southern Denmark • Aim: Symptom relief
Last updated Apr 29, 2026 15:03 UTC
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Fasting diet shows promise for IBD-Related depression
Symptom relief CompletedThis study looked at whether a short-term, plant-based low-calorie diet (called a fasting mimicking diet) could improve depressive symptoms in people with inflammatory bowel disease (IBD). 42 adults with IBD and mild-to-moderate depression completed three 5-day diet cycles. Resea…
Matched conditions: INFLAMMATORY BOWEL DISEASES
Phase: NA • Sponsor: University of Alberta • Aim: Symptom relief
Last updated Apr 29, 2026 15:01 UTC
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Lockdown's hidden toll: IBD Patients' mental health under the microscope
Knowledge-focused CompletedThis study looked at how being isolated during the COVID-19 pandemic affected the mental health of 232 people with inflammatory bowel disease (IBD). Researchers used questionnaires to measure feelings like depression and anxiety. The goal was to understand what factors made the p…
Matched conditions: INFLAMMATORY BOWEL DISEASES
Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust • Aim: Knowledge-focused
Last updated May 01, 2026 17:43 UTC
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Could the pill ease IBD flares? new study investigates
Knowledge-focused CompletedThis study looked at 50 women with inflammatory bowel disease (IBD) to understand how hormonal birth control might affect symptoms that get worse during their period. Researchers gathered information on which birth control methods women prefer and whether they would join a future…
Matched conditions: INFLAMMATORY BOWEL DISEASES
Sponsor: University of Utah • Aim: Knowledge-focused
Last updated May 01, 2026 17:42 UTC
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Coaching teens through a tough transition: pilot study tests new support model
Knowledge-focused CompletedThis study tested whether a transition coach could help 16-17 year olds with Juvenile Idiopathic Arthritis or Inflammatory Bowel Disease move from pediatric to adult healthcare. 27 teens took part in a pilot program to see if the coaching was practical and well-liked. The goal wa…
Matched conditions: INFLAMMATORY BOWEL DISEASES
Phase: NA • Sponsor: McMaster University • Aim: Knowledge-focused
Last updated May 01, 2026 16:01 UTC
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Gut bacteria linked to brain and bowel diseases in small study
Knowledge-focused CompletedThis study looked at gut bacteria in 15 people with inflammatory bowel disease (IBD) or Parkinson's disease, comparing them to healthy individuals. Researchers wanted to see if certain bacteria leak from the gut into the blood. The goal was to better understand how gut health rel…
Matched conditions: INFLAMMATORY BOWEL DISEASES
Phase: NA • Sponsor: Hôpital Européen Marseille • Aim: Knowledge-focused
Last updated May 01, 2026 15:59 UTC
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Healthy volunteers help test new inflammatory bowel disease drug
Knowledge-focused CompletedThis early-stage study tested a new oral drug, IPG11406, in 66 healthy adults to see if it is safe and how the body processes it. Participants received either the drug or a placebo. The goal was not to treat any disease, but to gather important safety and dosing information for f…
Matched conditions: INFLAMMATORY BOWEL DISEASES
Phase: PHASE1 • Sponsor: Nanjing Immunophage Biotech Co., Ltd • Aim: Knowledge-focused
Last updated May 01, 2026 15:56 UTC
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IBD patients face hidden oral health struggles, study reveals
Knowledge-focused CompletedThis study looked at how inflammatory bowel disease (IBD) affects oral health and daily life. Researchers compared 138 adults with IBD to people without IBD, using a questionnaire to measure oral health-related quality of life. The goal was to identify factors like medication or …
Matched conditions: INFLAMMATORY BOWEL DISEASES
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:51 UTC
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New biologics for Crohn's: Real-World results from china
Knowledge-focused CompletedThis study looked back at 50 adults with Crohn's disease who were treated with two newer biologic drugs, Ustekinumab and Vedolizumab. The goal was to see how well the drugs controlled the disease and what side effects occurred. Researchers also wanted to find out which patient fa…
Matched conditions: INFLAMMATORY BOWEL DISEASES
Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:49 UTC
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Which scope spots trouble better? study tests two colonoscopy techniques for IBD patients
Knowledge-focused CompletedThis study looked at 211 adults with long-standing inflammatory bowel disease (IBD) to see which colonoscopy method finds precancerous growths better: high-definition white light or dye spraying. Both are standard techniques used during screening. The goal was to learn which appr…
Matched conditions: INFLAMMATORY BOWEL DISEASES
Phase: NA • Sponsor: Beth Israel Deaconess Medical Center • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:48 UTC
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New tool aims to help nurses tackle Men's sexual health in IBD care
Knowledge-focused CompletedThis study aimed to create a tool to help nurses better assess and care for the sexual health needs of men with inflammatory bowel disease (IBD). Researchers worked with 792 participants, including men with IBD and healthcare staff, to understand current gaps and develop a practi…
Matched conditions: INFLAMMATORY BOWEL DISEASES
Sponsor: York Teaching Hospitals NHS Foundation Trust • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:03 UTC
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Real-World study tracks IBD Patients' choice of vedolizumab injection vs. infusion
Knowledge-focused CompletedThis study watched 92 adults with Crohn's disease or ulcerative colitis as they received vedolizumab either as an IV infusion or a shot under the skin. Researchers did not assign treatments—they simply recorded what patients and their doctors decided, and how long patients stayed…
Matched conditions: INFLAMMATORY BOWEL DISEASES
Sponsor: Takeda • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:03 UTC
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Mini-Guts grown from patient biopsies to test new therapies
Knowledge-focused CompletedThis study took small tissue samples from 16 people with and without inflammatory bowel disease (IBD) during routine colonoscopies. Researchers grew these samples into mini-organs called organoids in the lab. The goal was to see if they could reliably create these organoids and t…
Matched conditions: INFLAMMATORY BOWEL DISEASES
Phase: NA • Sponsor: Institut National de la Santé Et de la Recherche Médicale, France • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:03 UTC