INFLAMMATORY BOWEL DISEASES

This study tests whether adding vitamin D3 to standard anti-TNF therapy helps people with active Crohn's disease or ulcerative colitis feel better and have healthier gut bacteria. About 100 adults starting anti-TNF treatment will receive either vitamin D3 or a placebo for 14 week…

This study tests whether a personalized diet supplement (a type of starch) can increase helpful gut bacteria in children with Crohn's disease who are already on anti-TNF medication. The goal is to see if this approach can help maintain remission and reduce the need for higher med…

This study tests a thin probe placed through the nose into the intestine to measure how leaky the gut is. Researchers want to see if it can give accurate, real-time readings in 15 healthy adults. If it works, it could help diagnose gut diseases like Crohn's or environmental enter…

This study is testing a special temperature-sensing probe that can be used during a routine colonoscopy to measure heat in the lining of the colon. The goal is to see if this probe can help doctors detect inflammation in people with inflammatory bowel disease (IBD), including Cro…

This study collects blood, stool, and urine samples along with medical information from 1,000 people with Inflammatory Bowel Disease (IBD). The goal is to build a biobank that helps researchers better understand IBD and improve how it is treated. Participants must be between 18 a…

This study is a long-term registry that follows nearly 5,000 children with inflammatory bowel disease (Crohn's, ulcerative colitis, or indeterminate colitis) to monitor their safety and health over time. Researchers collect information on side effects from treatments like inflixi…

This study aims to better understand what causes certain gut diseases like inflammatory bowel disease (IBD), graft-versus-host disease (GVHD), and functional gut disorders. Researchers will collect blood and tissue samples from 1,000 patients to study their immune systems over ti…