Stem cell shot for pouchitis pulled before start
NCT ID NCT05578508
First seen Apr 23, 2026 · Last updated Jun 20, 2026 · Updated 12 times
Summary
This study planned to test whether injecting stem cells from a donor's bone marrow into the pouch (a surgically created internal reservoir) could safely treat severe pouchitis that didn't respond to standard treatments. The trial was withdrawn before enrolling any participants, so no results are available. The approach remains experimental.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
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Genom att skicka in godkänner du våra Användarvillkor
Locations
-
Cleveland Clinic
Cleveland, Ohio, 44195, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Allogeneic bone marrow derived mesenchymal stem cells (MSCs)
What this could lead to
If this approach had been tested, it might have pointed toward a new way to control severe pouchitis without surgery.
What could go wrong
The trial was withdrawn before any patients were enrolled, so we have no data on safety or effectiveness. Stem cell treatments are still experimental and carry risks like infection or immune reactions.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.