120,000 patients join hunt for hidden disease clues

NCT ID NCT04306939

Terminated Knowledge-focused Sponsor: University of Pittsburgh Source: ClinicalTrials.gov ↗

First seen Jan 07, 2026 · Last updated Jun 23, 2026 · Updated 30 times

Summary

This observational study will collect genetic and health information from 120,000 people with chronic conditions like pancreatitis, inflammatory bowel disease, diabetes, and arthritis. Researchers will analyze how genes, lifestyle, and other factors affect disease progression and quality of life. The goal is to find common disease mechanisms and identify new uses for existing medications.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, 15213, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help identify new drug targets and ways to repurpose existing medications for chronic diseases like pancreatitis, diabetes, and arthritis.

What could go wrong

This is an observational study, not a treatment trial. It will not directly test any therapy, and results may take years to influence clinical practice.

Conditions

The condition(s) this trial relates to.

acute pancreatitis celiac disease cholecystitis cholelithiasis chronic diarrheal disease Chronic Disease chronic kidney disease Chronic Pain chronic pain syndrome chronic pancreatitis chronic renal failure syndrome congenital bile acid synthesis defect constipation disorder Crohn disease cystic fibrosis diabetes mellitus Dyslipidemias exocrine pancreatic insufficiency Fibrosis gastritis hepatitis hyperlipidemia inflammatory bowel disease inherited lipid metabolism disorder irritable bowel syndrome metabolic dysfunction-associated steatohepatitis metabolic dysfunction-associated steatotic liver disease multiple sclerosis Pancreatic Cyst pancreatic intraductal papillary-mucinous neoplasm pancreatitis primary biliary cholangitis rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE PANCREATITIS BILE ACID SYNTHESIS DEFECT BILIARY CIRRHOSIS CELIAC DISEASE CHOLECYSTITIS CHOLELITHIASES CHRONIC DISEASE CHRONIC KIDNEY DISEASES CHRONIC KIDNEY DISEASES CHRONIC PAIN CHRONIC PANCREATITIS CONSTIPATION - FUNCTIONAL CONSTIPATION CHRONIC IDIOPATHIC CROHN DISEASE CYST PANCREAS CYST PANCREAS CYSTIC FIBROSIS DIABETES MELLITUS DIARRHEA CHRONIC DYSLIPIDEMIAS GASTRITIS HEPATITIS INFLAMMATORY BOWEL DISEASES INFLAMMATORY BOWEL DISEASES IPMN IRRITABLE BOWEL SYNDROME MULTIPLE SCLEROSIS NASH - NONALCOHOLIC STEATOHEPATITIS PANCREATIC EXOCRINE INSUFFICIENCY RHEUMATOID ARTHRITIS