CHRONIC PANCREATITIS

This study is testing if adding a patient's own bone marrow stem cells to a special pancreas transplant helps the insulin-producing cells survive and work better. It's for adults with severe chronic pancreatitis who are scheduled to have their pancreas removed and their own insul…

This study aims to develop a better test for diagnosing a specific type of diabetes caused by pancreatic cancer or chronic pancreatitis. Researchers will give participants a standardized meal drink and then measure hormone levels in their blood to see how the pancreas responds. T…

This study is testing a new blood test designed to find people with chronic or recurrent pancreatitis who have trouble absorbing fat from their food, a condition that often goes undetected. Researchers will enroll 80 participants to see if the test can identify those who might be…

This study is testing a new pain assessment tool to see if it can predict which patients with chronic pancreatitis will get relief from standard endoscopic or surgical treatments. Researchers will enroll 150 adults with chronic pancreatitis who are already scheduled for one of th…

This study is testing a new artificial intelligence (AI) system designed to help doctors diagnose and manage pancreatic diseases from CT scans. It will compare the AI's recommendations for surgery or monitoring against the decisions of experienced doctors in 2,000 patients. The m…

This early pilot study is testing whether simvastatin, a common cholesterol medication, can help reduce pain and improve quality of life for people with chronic or recurrent pancreatitis. The study will enroll 90 adults to take either simvastatin or a placebo pill for six months,…

This early-stage study is testing whether adding an existing epilepsy drug, lacosamide, to standard opioid painkillers is safe and tolerable for adults with chronic pancreatitis. The main goal is to see if the combination helps reduce severe abdominal pain and might allow patient…

This study is testing whether Scrambler Therapy, a non-invasive device that delivers gentle electrical signals through the skin, can help reduce severe abdominal pain in adults with chronic pancreatitis. About 40 participants who still have pain despite standard treatments will r…

This study is collecting information on a procedure that temporarily blocks nerves to manage severe pain from chronic pancreatitis. Researchers will track 35 patients for 24 weeks to see if the procedure reduces their pain and their need for opioid painkillers. The goal is to gat…

This study is testing whether a daily soy tomato juice drink is safe and tolerable for people with recurrent or chronic pancreatitis. All 35 participants will drink the juice for four weeks while researchers check for side effects and measure inflammation levels. The goal is to s…

This small, early-stage study is checking if it's practical to test a vitamin D-based medication called paricalcitol for chronic pancreatitis. It will involve 24 adults to see if the drug is well-tolerated and might improve their quality of life and pain. The main goal is to gath…

This study is testing an internet-delivered program that teaches pain self-management skills to adults with chronic or recurrent acute pancreatitis. Participants will learn techniques like relaxation and activity pacing to help reduce their pain and its impact on daily life. The …

This study is creating a registry to track the long-term results of specialized endoscopic ultrasound procedures used to treat various digestive problems. Researchers will follow 510 patients who undergo these procedures for conditions like pancreatitis, gallbladder issues, and d…

This study aims to find brain and body signals that can predict which patients with chronic pancreatitis will get long-term pain relief from a common endoscopic procedure. Researchers will enroll 100 adults already scheduled for the treatment and track their pain, function, and m…

This study aims to find early warning signs of pancreatic cancer by tracking people at higher risk. Researchers will collect health information and blood samples from 1250 participants over time. The goal is to spot patterns that could lead to earlier detection and better surviva…

This study is creating a large collection of medical information and biological samples from people with various pancreatic conditions. Researchers will collect blood, saliva, leftover tissue, and survey data from up to 20,000 participants. The goal is to build a resource that he…

This study is creating a large registry of people with pancreatic diseases or who are at high risk for pancreatic cancer. Researchers will collect health information and blood samples from participants to learn how family history, genetics, and other factors contribute to disease…

This study aims to better understand the chronic pain experienced by people with pancreatitis. Researchers will use a special pain mapping test on 500 participants, including healthy volunteers and patients, to see if certain pain patterns can predict who will benefit from treatm…

This study aims to learn more about children who get repeated or long-term pancreatitis. Researchers will collect blood, saliva, urine, and stool samples from up to 1,600 children under 18 to look for genetic signs that might show who is at higher risk for developing pancreatic c…

This study aims to understand how well transplanted insulin-producing cells work in people with chronic pancreatitis who have their pancreas removed. Researchers will collect blood samples from 100 participants to track markers of inflammation and cell function. The goal is to ga…