Could a special starch help heal gut bacteria in kids with IBD?
NCT ID NCT04522271
First seen Jan 31, 2026 · Last updated Jun 23, 2026 · Updated 20 times
Summary
This pilot study tests whether a plant-based resistant starch, tailored to each child's gut bacteria, can improve gut health in 80 children with Crohn's disease or ulcerative colitis. Participants take the starch or a placebo for a period, and researchers measure changes in gut microbiome and butyrate production. The goal is to see if this dietary approach can help manage inflammatory bowel disease.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Children's Hospital of Eastern Ontario
Ottawa, Ontario, K1H 8L1, Canada
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
plant-based resistant starch
What this could lead to
If it works, this could point toward a dietary approach to help manage inflammatory bowel disease by restoring a healthier gut microbiome.
What could go wrong
This is a small, early pilot study with only 80 participants, so results may not apply widely. The intervention is a dietary supplement, not a drug, so any benefit is likely modest and supportive.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.