Could a common heart drug ease ulcerative colitis?
NCT ID NCT05567068
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether adding atorvastatin (a cholesterol-lowering drug) to standard mesalamine treatment improves quality of life and reduces inflammation in adults with ulcerative colitis. 54 participants completed the trial. The goal was to see if the drug's anti-inflammatory effects could help control the disease without needing stronger medications.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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54 people
The number who actually took part.
- Started
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Feb 2023
- Finished
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Jun 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years * Both males and females will be included * Negative pregnancy test and effective contraception. Exclusion Criteria: * Breastfeeding * Significant liver and kidney function abnormalities * Colorectal cancer patients * Patients with severe UC * Patients taking rectal or systemic steroids * Patients taking immunosuppressives or biological therapies
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Faculty of Medicine, Mansoura University
Al Mansurah, 35511, Egypt
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Other studies related to the condition(s) this trial covers.
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