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Fasting diet shows promise for IBD-Related depression

NCT ID NCT05382897

First seen Nov 01, 2025 · Last updated Jun 10, 2026 · Updated 31 times

Summary

This study looked at whether a short-term, low-calorie plant-based diet (called a fasting mimicking diet) could help reduce depressive symptoms in people with inflammatory bowel disease (IBD). 42 adults with mild-to-moderate depression and IBD completed three 5-day diet cycles. Researchers measured changes in mood, gut bacteria, and immune function to see if this diet could be a safe way to improve mental health.

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Contacts and locations

Locations

  • University of Alberta Hospital

    Edmonton, Alberta, T6G 2E1, Canada

  • University of Alberta Human Nutrition Research Unit

    Edmonton, Alberta, T6G 2E1, Canada

Conditions

The condition(s) this trial relates to.

Crohn disease Depression Fasting inflammatory bowel disease ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.