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Which scope spots trouble better? study tests two colonoscopy techniques for IBD patients

NCT ID NCT04191655

Knowledge-focused Sponsor: Beth Israel Deaconess Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 211 adults with long-standing inflammatory bowel disease (IBD) to see which colonoscopy method finds precancerous growths better: high-definition white light or dye spraying. Participants had IBD for at least eight years. The goal was to improve cancer screening in this higher-risk group.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

211 people

The number who actually took part.

Started

Apr 2019

Finished

Jan 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patient age ≥18yr old 2. History of UC or colonic Crohn's disease or unclassified colitis patients with or without colonic adenoma history 3. Duration of ≥ eight years since diagnosis, or any duration with a diagnosis of primary sclerosing cholangitis 4. Mucosal lesion involves ≥ 1/3 of the colon Exclusion Criteria: 1. History of colorectal cancer 2. History of total colectomy 3. Prior colonoscopy within the last 6 months 4. Allergy to dye spray 5. Poor bowel preparation 6. Unable to provide informed consent 7. Severe inflammation preventing visualization of the mucosa during the procedure.

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Conditions

The condition(s) this trial relates to.

colon dysplasia Crohn disease Crohn's colitis indeterminate colitis inflammatory bowel disease ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colon dysplasia Crohn colitis Indeterminate colitis Inflammatory bowel diseases Ulcerative colitis

Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Lahey Hospital and Medical Center

    Burlington, Massachusetts, 01803, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.