HEART FAILURE WITH REDUCED EJECTION FRACTION
Clinical trials for HEART FAILURE WITH REDUCED EJECTION FRACTION explained in plain language.
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New pacing technique aims to improve life for heart failure patients
Disease control Recruiting nowThis study tests a newer pacing method (His or left bundle branch pacing) against the standard method (biventricular pacing) in over 2,000 adults with heart failure and a wide QRS or high pacing need. The goal is to see which approach better improves quality of life, reduces hosp…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated May 26, 2026 05:51 UTC
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Smartphone app could Fine-Tune heart failure drugs
Disease control Recruiting nowThis study tests a digital platform that helps doctors adjust heart failure medications remotely. About 252 adults with heart failure and reduced pumping function will use the app to report symptoms and vital signs, while an algorithm suggests medication changes. The goal is to s…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Beijing Anzhen Hospital • Aim: Disease control
Last updated May 26, 2026 05:47 UTC
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New drug aims to cut heart failure hospitalizations and deaths
Disease control Recruiting nowThis study tests an investigational drug called omecamtiv mecarbil in 1800 adults with severe heart failure and a very weak heart pump. The goal is to see if the drug can lower the chance of heart failure worsening, needing a heart pump or transplant, or dying. Participants will …
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE3 • Sponsor: Cytokinetics • Aim: Disease control
Last updated May 26, 2026 05:40 UTC
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Heart failure drug withdrawal trial aims to free patients from lifelong pills
Disease control Recruiting nowThis study looks at people whose heart failure got better after treating a fast heart rhythm (like atrial fibrillation). It tests whether slowly stopping their heart failure medicines is as safe as continuing them. About 348 adults in Denmark will be randomly assigned to either w…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE2, PHASE3 • Sponsor: Herlev and Gentofte Hospital • Aim: Disease control
Last updated May 26, 2026 04:38 UTC
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Heart failure patients: could a High-Protein diet and resistance training be the key to stronger muscles?
Disease control Recruiting nowThis study tests whether a special diet (DASH diet with extra protein) combined with resistance exercise can help people with heart failure maintain muscle mass, improve their ability to exercise, and feel better overall. Researchers will enroll 100 adults with heart failure and …
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Medical University of Silesia • Aim: Disease control
Last updated May 26, 2026 04:38 UTC
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New device zaps diaphragm to help failing hearts
Disease control Recruiting nowThis study tests a device that stimulates the diaphragm muscle to help people with heart failure breathe easier and improve heart function. About 270 adults with moderate heart failure will receive the device plus standard medications, or standard medications alone. The goal is t…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: VisCardia Inc. • Aim: Disease control
Last updated May 22, 2026 14:01 UTC
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Can a smartphone app replace hospital rehab for heart failure patients?
Disease control Recruiting nowThis study tests a home-based cardiac rehabilitation program delivered through a custom mobile app for 100 adults with heart failure. Participants are randomly assigned to either the app-based program or usual care. The goal is to see if the app helps increase physical activity, …
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Disease control
Last updated May 19, 2026 11:47 UTC
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Digital heart helper: swiss trial tests telemedicine for better heart failure care
Disease control Recruiting nowThis study tests whether using telemedicine (smartphone or tablet check-ins) can help doctors fine-tune heart failure medications better than standard care. About 140 adults hospitalized with heart failure will be followed for 3 months after discharge. The goal is to see if digit…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Can a smartphone app help heart failure patients feel more in control?
Symptom relief Recruiting nowThis study tests a digital support program for 240 adults with heart failure. Participants use the program for six months via a secure online portal. The goal is to see if it helps them feel more in control of their condition, improves quality of life, and supports self-care. The…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Linkoeping University • Aim: Symptom relief
Last updated May 26, 2026 05:45 UTC
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No-Implant heart shunt could offer new relief for heart failure patients
Symptom relief Recruiting nowThis early study is testing a new device that creates a temporary opening between the upper chambers of the heart to help blood flow more easily, without leaving any implant behind. The goal is to see if the procedure is safe and can improve symptoms in people with advanced heart…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: InterShunt Technologies, Inc. • Aim: Symptom relief
Last updated May 26, 2026 05:43 UTC
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New heart failure drug HJB647 enters early safety testing
Symptom relief Recruiting nowThis early-stage study tests the safety and tolerability of a new drug called HJB647 in 12 adults with stable heart failure and reduced pumping ability. Participants will receive two different doses of the drug or a placebo in a crossover design. The goal is to see if the drug is…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE1 • Sponsor: Novartis Pharmaceuticals • Aim: Symptom relief
Last updated May 20, 2026 11:55 UTC
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Breathing training may supercharge heart rehab in heart failure patients
Symptom relief Recruiting nowThis study looks at whether adding special breathing muscle training to standard cardiac rehabilitation can improve how well the heart and muscles work during exercise in people with heart failure. About 70 adults with heart failure and reduced pumping ability will take part. The…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated May 19, 2026 11:59 UTC
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Scientists probe hidden cause of right heart failure
Knowledge-focused Recruiting nowThis study aims to understand why the right side of the heart fails in people with heart failure and high blood pressure in the lungs. Researchers will look at heart muscle samples from 50 adults to find the best ways to diagnose and test new treatments for this condition. The go…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated May 26, 2026 05:48 UTC
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Heart failure study aims to match patients with the right medications
Knowledge-focused Recruiting nowThis study is observing 3,000 people with various types of heart failure to learn how the disease develops and progresses over time. Researchers will collect medical data, blood samples, and imaging to identify distinct groups of heart failure. The goal is to help doctors choose …
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 05:41 UTC
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New study probes how diabetes drug boosts heart fuel
Knowledge-focused Recruiting nowThis early-phase study looks at how SGLT2 inhibitors raise ketone levels and affect heart and muscle energy in people with type 2 diabetes and heart failure. Researchers will measure changes in heart energy molecules and walking ability. The goal is to understand the drug's effec…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: EARLY_PHASE1 • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Knowledge-focused
Last updated May 20, 2026 11:58 UTC
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Gene test could personalize heart failure treatment
Knowledge-focused Recruiting nowThis study looks at whether a person's genetic makeup affects how well the heart drug metoprolol works for heart failure. Researchers will give the drug to 100 people with heart failure and track their heart function and drug levels. The goal is to learn if a genetic score can he…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE4 • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated May 18, 2026 12:08 UTC
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40,000 heart patients monitored in real time
Knowledge-focused Recruiting nowThis study is creating a live registry to track heart failure patients across the Yale New Haven Health System. Researchers will monitor hospitalizations and use of recommended treatments in up to 40,000 participants. The goal is to better understand and improve heart failure car…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: Yale University • Aim: Knowledge-focused
Last updated May 14, 2026 12:06 UTC