HEART FAILURE WITH REDUCED EJECTION FRACTION
Clinical trials for HEART FAILURE WITH REDUCED EJECTION FRACTION explained in plain language.
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Major heart failure drug trial aims to keep patients out of hospital
Disease control Recruiting nowThis study is testing whether a new drug called omecamtiv mecarbil can help people with severe heart failure live longer and avoid hospital visits, transplants, or strokes. About 1,800 participants will receive either the drug or a placebo pill for up to three years while continu…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE3 • Sponsor: Cytokinetics • Aim: Disease control
Last updated Apr 03, 2026 20:55 UTC
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Digital tool aims to give heart patients more control
Disease control Recruiting nowThis study is testing a 6-month digital support program designed to help people with heart failure better manage their condition. Researchers want to see if using this program improves patients' sense of control over their health, their quality of life, and their self-care habits…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Linkoeping University • Aim: Disease control
Last updated Apr 03, 2026 20:55 UTC
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Heart failure study questions need for defibrillators in Low-Risk patients
Disease control Recruiting nowThis study aims to find out if heart failure patients at low risk for dangerous heart rhythms need an implantable defibrillator (ICD) or if they can do just as well with medication alone. It will enroll 3,290 adults with heart failure who are already on stable, optimal medication…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: University of Rochester • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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Danish trial tests if recovered heart patients can ditch lifelong pills
Disease control Recruiting nowThis study is for people whose heart failure was likely caused by a fast, irregular heartbeat (atrial fibrillation). It tests if patients who have fully recovered their heart function after their rhythm is controlled can safely stop their heart failure medications. Researchers wi…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: PHASE2, PHASE3 • Sponsor: Herlev and Gentofte Hospital • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Phone app aims to keep heart patients out of hospital
Disease control Recruiting nowThis study is testing whether using telemedicine (remote monitoring via phone or tablet) can help doctors safely adjust heart failure medications for patients after they leave the hospital. It compares this remote approach to usual care to see if it leads to better medication use…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: University Hospital, Basel, Switzerland • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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No implant needed: new heart procedure aims to ease heart failure
Disease control Recruiting nowThis early study is testing a new heart procedure that creates a small opening between the upper heart chambers to relieve pressure buildup. The procedure uses a special device but leaves no permanent implant behind. Researchers want to see if this approach is safe and might help…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: InterShunt Technologies, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Heart failure breakthrough? new pacemaker technique aims to cut hospital visits
Disease control Recruiting nowThis large study is testing whether a newer pacemaker technique (His or Left Bundle Branch Pacing) works better than the standard method (Biventricular Pacing) for people with heart failure and a weak heart pump. It will enroll over 2,100 adults to see which method is more effect…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated Mar 27, 2026 12:38 UTC
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Phone app aims to bring heart rehab home
Disease control Recruiting nowThis study is testing whether a home-based cardiac rehabilitation program delivered through a custom mobile app can help people with heart failure. The program aims to improve physical activity, quality of life, and reduce hospital visits by guiding exercise and healthy behaviors…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Vanderbilt University Medical Center • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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Can stronger breathing muscles help heart failure patients exercise better?
Symptom relief Recruiting nowThis study is testing whether adding specific breathing muscle exercises to standard cardiac rehabilitation helps people with heart failure. It will measure if this combination improves blood flow to the legs and reduces the oxygen cost of breathing during exercise. The goal is t…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Apr 03, 2026 14:41 UTC
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Scientists probe hidden link between diabetes drug and heart health
Knowledge-focused Recruiting nowThis early-phase study aims to understand how a common diabetes medication (empagliflozin) affects muscle energy production and heart function in people who have both type 2 diabetes and heart failure. Researchers will measure changes in muscle chemicals and heart performance ove…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Phase: EARLY_PHASE1 • Sponsor: The University of Texas Health Science Center at San Antonio • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:31 UTC
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Yale launches massive 40,000-Patient heart failure tracking project
Knowledge-focused Recruiting nowThis study is creating a live registry using the health records of 40,000 heart failure patients within the Yale New Haven Health System. Its purpose is to monitor patients in real-time to identify gaps in recommended treatments and understand patterns in hospital readmissions. T…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: Yale University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC
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Massive study aims to crack the code of heart failure
Knowledge-focused Recruiting nowThis study is collecting detailed health information from 3,000 people with and without heart failure to better understand how different types of the condition develop and progress. Researchers will track participants over time, analyzing blood samples, genetic data, and heart im…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:38 UTC
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Scientists search for hidden heart failure clues
Knowledge-focused Recruiting nowThis study aims to find better ways to spot and understand right heart failure in people who have a weakened main heart pump and high blood pressure in their lungs. Researchers will test 50 patients during exercise and take tiny heart tissue samples to look for early signs of mus…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:07 UTC