FRAILTY

This study tested whether combining a healthy diet, exercise, and the diabetes drug metformin can reverse frailty and obesity in older veterans aged 65-85. 114 participants were enrolled. The goal was to improve physical function and strength, not to cure the underlying condition…

This study tested a home-based exercise program for older adults who are starting to become frail. The goal was to see if tailored exercises could help them maintain strength and function after being in the hospital. Forty people aged 60 and older participated, and the program fo…

This study looked at whether it is safe and helpful to reduce blood pressure medications in frail older adults living in long-term care. Over 500 participants with low blood pressure were randomly assigned to either have their medications slowly reduced or to continue usual care.…

This study tested a system called SAIF that helps assess and manage frailty in people aged 60 and older. The goal was to see if it could reduce frailty risk and slow its progression. 105 participants used the system, and researchers measured changes in physical performance and fr…

This study tested whether interactive physical therapy tools could help frail older adults recover after open heart surgery. 153 participants aged 65 and older were enrolled. The therapy aimed to improve walking ability, strength, balance, and quality of life, while reducing fear…

This study tested a home-based lifestyle program for adults aged 50-85 with type 2 diabetes and chronic kidney disease. The program focused on healthier eating and exercises to prevent frailty, which causes muscle weakness and makes daily tasks harder. 120 participants were assig…

This study looked at whether a 12-week program combining strength training with Taiwanese opera activities could help older adults (65+) stay physically fit and delay frailty. 120 community-dwelling seniors in Taipei took part, with half doing the program and half continuing thei…

This study tested a special educational program called FRAGSALUD to help prevent and treat frailty in older adults living in the community. Frailty makes seniors more vulnerable to falls, disability, and other health problems. The program taught participants about healthy aging a…

This study tested a personalized training program designed to prevent functional decline in frail older adults who are not yet disabled. Researchers enrolled 80 frail participants aged 65 and older, dividing them into an experimental group receiving the personalized program and a…

This study tested a program that combines diet advice, exercise, medication review, and social support to prevent frailty in older adults who are already showing early signs of weakness. 232 people aged 70 and older took part. Half received the program, and half received usual ca…

This study looked at whether a simple home exercise program and/or protein supplements could help prevent falls in older adults at risk of muscle loss (sarcopenia). Over 800 seniors with signs of frailty or a recent fall took part. The goal was to see if these approaches, alone o…

This study tested a 12-week exercise program called Vivifrail in 80 elderly residents of long-term care facilities. Participants were assigned to either the exercise group or a control group. The program aimed to improve physical performance, grip strength, and reduce fall risk. …

This study tested whether adding a special program focused on daily activities (like bathing and dressing) to usual home rehab helps older adults function better. 47 people aged 65+ with multiple health issues took part. The program aimed to improve motor skills and independence …

This pilot study tested whether combining active video games (exergaming) with resistance training could reduce frailty in nursing home residents. Thirty older adults who were frail or pre-frail took part. The goal was to see if this fun, combined exercise approach could improve …

This study tested whether structured music improvisation sessions led by professional musicians could improve the mental and physical health of older adults with dementia. Seven participants with mild to moderate dementia took part, along with their caregivers. The goal was to se…

This study tested a nurse-led education program for dry mouth in 70 adults with life-limiting conditions or frailty. The program taught patients about causes and treatments for dry mouth and created a personalized plan. The goal was to see if this approach reduced dry mouth sever…

This study looked at whether a game called hemsball can help older men improve their balance, reduce fear of movement, and lower frailty. 86 men aged 65 and older played hemsball for 60 minutes, three times a week, for eight weeks. Results showed that hemsball activity was effect…

This study tested if a 12-week home-based walking program could help people with heart failure feel less depressed, less frail, and have a better quality of life. 68 adults hospitalized for heart failure were split into two groups: one got standard health education, and the other…

This study tested whether a smartphone app called Ghostly can help hospitalized patients—including those recovering from stroke, COVID-19, or frailty—do strength exercises to rebuild muscle. Fifteen participants used the app during their hospital stay, and researchers measured ch…

This pilot study tested whether a green tea extract called EGCG is safe and practical for older cancer survivors who are frail or pre-frail. 24 people aged 65+ who had finished cancer treatment took EGCG or a placebo for 12 weeks. The goal was to see if the supplement could help …

This study tested a 10-week program that combines resistance exercises with cognitive tasks (like memory games) in 38 frail older adults with chronic musculoskeletal pain. The goal was to see if the program is feasible and can improve frailty and thinking. Participants did superv…

This study tested a program called DAPPER for African American women aged 50 and older who had pain, depressive symptoms, and trouble moving around. Participants received 8 nurse visits at home to help manage their pain and mood. The study measured changes in pain intensity and d…

This study looked at 2,744 older adults (65+) who came to the emergency room for non-injury reasons. Researchers checked how well different early warning scores—like NEWS and qSOFA—could predict who would die within 28 days. The goal was to find which score works best for this ag…

This study looked at whether two simple frailty tests (G8 and VES-13) can predict serious side effects from chemotherapy in people 65 and older with gastrointestinal cancers. Researchers followed 72 patients during their treatment to see if those who were frail had more toxicity.…

This study looked at 58 older adults (65+) to find the best dose of remimazolam, a sedative, for putting them to sleep before surgery. Researchers used a special breathing monitor to watch for subtle breathing problems. The goal was to make anesthesia safer for frail elderly pati…

This study tested whether a structured program combining exercise, nutrition advice, and psychological support is practical and safe for adults with cirrhosis waiting for a liver transplant. 25 participants were enrolled. The goal was to see if patients could stick with the progr…

This study looked at why some people with COPD lose muscle mass and strength (sarcopenia). Researchers measured exercise ability, frailty, and breathing in 42 adults with COPD. The goal was to find factors that affect sarcopenia in this group.

This study tested whether a program combining exercises and nutritional supplements is practical for frail older adults recovering in skilled nursing facilities. Researchers enrolled 50 people aged 65 and older who lived at home before a hospital stay. The main goal was to see ho…

This small pilot study looked at whether a thinking and memory program, called cognitive stimulation therapy, could work for stroke survivors who also show early signs of frailty. Ten stroke survivors and their carers took part in focus groups to share their thoughts. The goal wa…

This study looked at whether a simple frailty score (Rockwood Frailty Index) can predict how long older adults might live after being treated at home instead of in a hospital. Researchers followed 2,610 patients aged 65 and older who were in a Hospital-at-Home program. They found…

This study examined 79 older adults with hip fractures to see if the balance of specific muscles around the hip, rather than overall muscle loss, influences the type of fracture. Using CT scans, researchers measured the gluteus medius and psoas muscles. The goal was to understand…

This study checked how well two digital hand-grip devices measure muscle strength and tiredness in older adults. Over 400 people aged 60+ took part. The goal was to see if these tools can reliably help identify frailty and muscle loss.

This study tested whether a program combining physical therapy, nutrition advice, and meditation is practical for older adults (70+ or 65+ with high risk) before major surgery. The goal was to see if participants could complete enough sessions, not to measure health outcomes. 30 …

This study examined over 200,000 adults hospitalized with cardiogenic shock—a life-threatening condition where the heart suddenly can't pump enough blood. Researchers wanted to see if frailty (physical weakness) could help predict who would survive, and whether age changes that l…

This study looked at 200 older adults (65+) having planned surgery for colorectal cancer. Researchers used a simple frailty test before surgery to see if it could predict complications like infections or longer hospital stays. The goal is to help doctors better plan care and impr…

This study followed 211 older adults who were hospitalized with COVID-19 to see how their ability to move, think, and do daily tasks changed over time. Researchers measured recovery using standard tests of mobility and cognition. The goal is to understand the long-term effects of…

This study tracked 295 adults who had high-risk surgery for stomach, esophagus, pancreas, or liver cancer. Researchers measured quality of life before surgery and again at 6 and 12 months after. They also asked patients and their family members if they regretted the decision to h…

This study looked at how the COVID-19 pandemic affected the health of people aged 75 and older and their caregivers. Researchers analyzed medical records and interviewed participants to understand changes in health, daily routines, and care needs. The goal is to find ways to impr…

This study looked at the link between gut bacteria and frailty in 14 older adults (over 65) who were frail or pre-frail. Participants took part in a 12-month healthy aging education program. Researchers collected stool samples to analyze gut bacteria and measured frailty, physica…

This study looked at 164 adults aged 65 and older who had a colonoscopy with sedation. Researchers wanted to see if frailty and the type of sedative used (propofol or dexmedetomidine) affected thinking and memory after the procedure. Participants took a simple mental test before …

This study looked at 100 patients aged 80 and older who had major abdominal surgery to find out what factors best predict death within 30 days. Researchers focused on frailty (a measure of physical weakness) and physiological reserve (body's ability to handle stress) using simple…

This study looked at 85 older adults (70+) in Spain to see if ultrasound scans and blood tests can help measure muscle quality and frailty. Participants were divided into groups, with one group doing a physical exercise program. The goal was to find better ways to detect early si…

This study surveyed 47 older adults (65+) in France to understand how much they know about cannabidiol (CBD) and whether they use it. The goal was to gather information to help guide safe CBD use and prevent potential side effects in this age group. Participants completed a quest…