Can exercise, medication review, and nutrition boost frailty? small study says maybe.
NCT ID NCT07637890
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tested whether a 3-month program combining group exercise, medication review, and nutrition workshops could be practically delivered in primary care for frail adults over 65. Researchers recruited 32 participants from two health centers and tracked feasibility, satisfaction, and health measures like mobility and strength. The goal was to see if the program could run smoothly before planning a larger trial.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Multi-component intervention: physical exercise, polypharmacy review, and nutritional care
- What this could lead to
- If successful, this could pave the way for a larger trial testing a practical program to help frail older adults stay stronger and healthier.
- What could go wrong
- This is a small pilot study with only 32 participants, so results may not apply to everyone. The main goal was feasibility, not proving effectiveness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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32 people
The number who actually took part.
- Started
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Dec 2024
- Finished
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Sep 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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65 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * \>65 years old * Barthel \>90 points (independent) * Short Physical Performance Battery \<10 points (frail) Exclusion Criteria: * Having a terminal condition * Suffering from pathologies with a poor prognosis * Having difficulty in performing physical activities * Not being able to communicate fluently in Spanish * Presenting intellectual disabilities
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Biogipuzkoa Health Research Institute. Primary Care Group. Epidemiology, Public Health and Primary Care Area.
San Sebastián, Gipuzkoa, 20014, Spain
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