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Frailty may be key to predicting surgery survival in the very old

NCT ID NCT07440095

Knowledge-focused Sponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study examines whether frailty and simple blood tests can predict which patients aged 80 and older are most likely to die within 30 days after major abdominal surgery. Researchers will review records of 100 patients to see if a frailty index and lab markers like albumin and hemoglobin offer better risk prediction than standard methods. The goal is to improve surgical decision-making and pre-surgery care for the oldest patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors better identify which very elderly patients are at highest risk after major abdominal surgery, leading to more informed decisions and possibly pre-surgery strengthening programs.
What could go wrong
This is a small, retrospective study (100 patients) from a single hospital, so results may not apply to all older adults. It only looks at risk factors, not a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

100 people

The number who actually took part.

Started

Mar 2026

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of "old-old" patients (aged 80 years and older) who underwent major abdominal surgery at a tertiary oncology center (Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital) between January 2022 and December 2025. This population includes patients who received surgical interventions in the departments of surgical oncology, gynecologic oncology, and urologic oncology. The sample represents a high-risk geriatric group undergoing complex oncological or major abdominal procedures, where frailty and physiological reserve are critical factors for survival.

Ages

80 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 80 years and older * Underwent major abdominal surgery between January 2022 and December 2025 * Availability of at least 30 days of postoperative follow-up data * Complete medical records available in the hospital information system Exclusion Criteria: * Patients under 80 years of age * Underwent surgical procedures other than major abdominal surgery * Missing or incomplete follow-up data within the first 30 days postoperatively * Insufficient data for the assessment of frailty (mFI-5) or physiological reserve parameters (e.g., missing preoperative laboratory values)

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Conditions

The condition(s) this trial relates to.

Frailty Postoperative Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Abdomen cancer Aged, 80 and over Frailty Postoperative complications

Contacts and locations

Locations

  • Dr. Abdurrahman Yurtaslan Ankara Oncology Education and Research Hospital Clinic of Anesthesiology and Rea

    Ankara, Yenimahalle, 06200, Turkey (Türkiye)

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